SEARCH:   Advanced

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Shi, Q. Articles by Hammond, W. P. Search for Related Content PubMed PubMed Citation Articles by Shi, Q. Articles by Hammond, W. P. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Evidence for Circulating Bone Marrow-Derived Endothelial Cells Qun Shi, Shahin Rafii, Moses Hong-De Wu, Errol S. Wijelath, Cong Yu, Atsushi Ishida, Yuji Fujita, Sudesh Kothari, Robert Mohle, Lester R. Sauvage, Malcom A.S. Moore, Rainer F. Storb, and William P. Hammond From the Departments of Surgery and Molecular Biology, The Hope Heart Institute and Providence Medical Center, Seattle, WA; the Hematology-Oncology Division, Cornell Medical College, New York, NY; the Fred Hutchinson Cancer Research Center, Seattle, WA; the Sloan-Kettering Cancer Research Center, New York, NY; and the Departments of Surgery and Medicine, University of Washington School of Medicine, Seattle, WA. It has been proposed that hematopoietic and endothelial cells are derived from a common cell, the hemangioblast. In this study, we demonstrate that a subset of CD34+ cells have the capacity to differentiate into endothelial cells in vitro in the presence of basic fibroblast growth factor, insulin-like growth factor-1, and vascular endothelial growth factor. These differentiated endothelial cells are CD34+, stain for von Willebrand factor (vWF), and incorporate acetylated low-density lipoprotein (LDL). This suggests the possible existence of a bone marrow-derived precursor endothelial cell. To demonstrate this phenomenon in vivo, we used a canine bone marrow transplantation model, in which the marrow cells from the donor and recipient are genetically distinct. Between 6 to 8 months after transplantation, a Dacron graft, made impervious to prevent capillary ingrowth from the surrounding perigraft tissue, was implanted in the descending thoracic aorta. After 12 weeks, the graft was retrieved, and cells with endothelial morphology were identified by silver nitrate staining. Using the di(CA)n and tetranucleotide (GAAA)n repeat polymorphisms to distinguish between the donor and recipient DNA, we observed that only donor alleles were detected in DNA from positively stained cells on the impervious Dacron graft. These results strongly suggest that a subset of CD34+ cells localized in the bone marrow can be mobilized to the peripheral circulation and can colonize endothelial flow surfaces of vascular prostheses. Blood, Vol. 92 No. 2 (July 15), 1998: pp. 362-367 © 1998 by the American Society of Hematology. CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: G. J. Madlambayan, J. M. Butler, K. Hosaka, M. Jorgensen, D. Fu, S. M. Guthrie, A. K. Shenoy, A. Brank, K. J. Russell, J. Otero, et al. Bone marrow stem and progenitor cell contribution to neovasculogenesis is dependent on model system with SDF-1 as a permissive trigger Blood, November 5, 2009; 114(19): 4310 - 4319. [Abstract] [Full Text] [PDF] T. E. Perry, M. Song, D. J. Despres, S. M. Kim, H. San, Z.-X. Yu, N. Raghavachari, J. Schnermann, R. O. Cannon III, and D. Orlic Bone marrow-derived cells do not repair endothelium in a mouse model of chronic endothelial cell dysfunction Cardiovasc Res, November 1, 2009; 84(2): 317 - 325. [Abstract] [Full Text] [PDF] J. Zavada, L. Kideryova, R. Pytlik, Z. Hruskova, and V. Tesar Reduced number of endothelial progenitor cells is predictive of early relapse in anti-neutrophil cytoplasmic antibody-associated vasculitis Rheumatology, October 1, 2009; 48(10): 1197 - 1201. [Abstract] [Full Text] [PDF] J. Xu and M.-H. Zou Molecular Insights and Therapeutic Targets for Diabetic Endothelial Dysfunction Circulation, September 29, 2009; 120(13): 1266 - 1286. [Full Text] [PDF] J. Moriya, T. Minamino, K. Tateno, N. Shimizu, Y. Kuwabara, Y. Sato, Y. Saito, and I. Komuro Long-Term Outcome of Therapeutic Neovascularization Using Peripheral Blood Mononuclear Cells for Limb Ischemia Circ Cardiovasc Interv, June 1, 2009; 2(3): 245 - 254. [Abstract] [Full Text] [PDF] W. Yao, A. L. Firth, R. S. Sacks, A. Ogawa, W. R. Auger, P. F. Fedullo, M. M. Madani, G. Y. Lin, N. Sakakibara, P. A. Thistlethwaite, et al. Identification of putative endothelial progenitor cells (CD34+CD133+Flk-1+) in endarterectomized tissue of patients with chronic thromboembolic pulmonary hypertension Am J Physiol Lung Cell Mol Physiol, June 1, 2009; 296(6): L870 - L878. [Abstract] [Full Text] [PDF] F. Tian, P. H. Liang, and L.-Y. Li Inhibition of endothelial progenitor cell differentiation by VEGI Blood, May 21, 2009; 113(21): 5352 - 5360. [Abstract] [Full Text] [PDF] D. P Sieveking and M. K. Ng Cell therapies for therapeutic angiogenesis: back to the bench Vascular Medicine, May 1, 2009; 14(2): 153 - 166. [Abstract] [PDF] S.-J. Kim, J.-S. Kim, J. Papadopoulos, S. Wook Kim, M. Maya, F. Zhang, J. He, D. Fan, R. Langley, and I. J. Fidler Circulating Monocytes Expressing CD31: Implications for Acute and Chronic Angiogenesis Am. J. Pathol., May 1, 2009; 174(5): 1972 - 1980. [Abstract] [Full Text] [PDF] E Robak, M Kierstan, B Cebula, A Krawczynska, A Sysa-Jedrzejowska, A Wierzbowska, P Smolewski, and T Robak Circulating endothelial cells and angiogenic proteins in patients with systemic lupus erythematosus Lupus, April 1, 2009; 18(4): 332 - 341. [Abstract] [PDF] D. Scharner, L. Rossig, G. Carmona, E. Chavakis, C. Urbich, A. Fischer, T.-B. Kang, D. Wallach, Y. J. Chiang, Y. L. Deribe, et al. Caspase-8 Is Involved in Neovascularization-Promoting Progenitor Cell Functions Arterioscler Thromb Vasc Biol, April 1, 2009; 29(4): 571 - 578. [Abstract] [Full Text] [PDF] M. R Placzek, I-M. Chung, H. M Macedo, S. Ismail, T. Mortera Blanco, M. Lim, J. Min Cha, I. Fauzi, Y. Kang, D. C.L Yeo, et al. Stem cell bioprocessing: fundamentals and principles J R Soc Interface, March 6, 2009; 6(32): 209 - 232. [Abstract] [Full Text] [PDF] R. Gulati and R. D. Simari Defining the potential for cell therapy for vascular disease using animal models Dis. Model. Mech., March 1, 2009; 2(3-4): 130 - 137. [Abstract] [Full Text] [PDF] H. Chen, R. A. Campbell, Y. Chang, M. Li, C. S. Wang, J. Li, E. Sanchez, M. Share, J. Steinberg, A. Berenson, et al. Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis Blood, February 26, 2009; 113(9): 1992 - 2002. [Abstract] [Full Text] [PDF] C. S. Bonder, W. Y. Sun, T. Matthews, C. Cassano, X. Li, H. S. Ramshaw, S. M. Pitson, A. F. Lopez, P. T. Coates, R. L. Proia, et al. Sphingosine kinase regulates the rate of endothelial progenitor cell differentiation Blood, February 26, 2009; 113(9): 2108 - 2117. [Abstract] [Full Text] [PDF] K. Yamahara and H. Itoh Potential use of endothelial progenitor cells for regeneration of the vasculature Therapeutic Advances in Cardiovascular Disease, February 1, 2009; 3(1): 17 - 27. [Abstract] [PDF] W.-P. T Ruifrok, R. A de Boer, A. Iwakura, M. Silver, K. Kusano, R. A Tio, and D. W Losordo Estradiol-induced, endothelial progenitor cell-mediated neovascularization in male mice with hind-limb ischemia Vascular Medicine, February 1, 2009; 14(1): 29 - 36. [Abstract] [PDF] A. Desai, A. Glaser, D. Liu, N. Raghavachari, A. Blum, G. Zalos, M. Lippincott, J. P. McCoy, P. J. Munson, M. A. Solomon, et al. Microarray-Based Characterization of a Colony Assay Used to Investigate Endothelial Progenitor Cells and Relevance to Endothelial Function in Humans Arterioscler Thromb Vasc Biol, January 1, 2009; 29(1): 121 - 127. [Abstract] [Full Text] [PDF] I. Al Mheid and A. A. Quyyumi Cell Therapy in Peripheral Arterial Disease Angiology, January 1, 2009; 59(6): 705 - 716. [Abstract] [PDF] Q. Hao, J. Liu, R. Pappu, H. Su, R. Rola, R. A. Gabriel, C. Z. Lee, W. L. Young, and G.-Y. Yang Contribution of Bone Marrow-Derived Cells Associated With Brain Angiogenesis Is Primarily Through CD69+ Arterioscler Thromb Vasc Biol, December 1, 2008; 28(12): 2151 - 2157. [Abstract] [Full Text] [PDF] T. Ziebart, C.-H. Yoon, T. Trepels, A. Wietelmann, T. Braun, F. Kiessling, S. Stein, M. Grez, C. Ihling, M. Muhly-Reinholz, et al. Sustained Persistence of Transplanted Proangiogenic Cells Contributes to Neovascularization and Cardiac Function After Ischemia Circ. Res., November 21, 2008; 103(11): 1327 - 1334. [Abstract] [Full Text] [PDF] H. Reinecke, E. Minami, W.-Z. Zhu, and M. A. Laflamme Cardiogenic Differentiation and Transdifferentiation of Progenitor Cells Circ. Res., November 7, 2008; 103(10): 1058 - 1071. [Abstract] [Full Text] [PDF] S. Murasawa and T. Asahara Review: Cardiogenic potential of endothelial progenitor cells Therapeutic Advances in Cardiovascular Disease, October 1, 2008; 2(5): 341 - 348. [Abstract] [PDF] K. Iwasaki, K. Kojima, S. Kodama, A. C. Paz, M. Chambers, M. Umezu, and C. A. Vacanti Bioengineered Three-Layered Robust and Elastic Artery Using Hemodynamically-Equivalent Pulsatile Bioreactor Circulation, September 30, 2008; 118(14_suppl_1): S52 - S57. [Abstract] [Full Text] [PDF] E. A. Silva, E.-S. Kim, H. J. Kong, and D. J. Mooney Material-based deployment enhances efficacy of endothelial progenitor cells PNAS, September 23, 2008; 105(38): 14347 - 14352. [Abstract] [Full Text] [PDF] A. S. Arbab, B. Janic, R. A. Knight, S. A. Anderson, E. Pawelczyk, A. M. Rad, E. J. Read, S. D. Pandit, and J. A. Frank Detection of migration of locally implanted AC133+ stem cells by cellular magnetic resonance imaging with histological findings FASEB J, September 1, 2008; 22(9): 3234 - 3246. [Abstract] [Full Text] [PDF] K. K. Hirschi, D. A. Ingram, and M. C. Yoder Assessing Identity, Phenotype, and Fate of Endothelial Progenitor Cells Arterioscler Thromb Vasc Biol, September 1, 2008; 28(9): 1584 - 1595. [Full Text] [PDF] R. Miller, V. Cirulli, G. R. Diaferia, S. Ninniri, G. Hardiman, B. E. Torbett, R. Benezra, and L. Crisa Switching-On Survival and Repair Response Programs in Islet Transplants by Bone Marrow-Derived Vasculogenic Cells Diabetes, September 1, 2008; 57(9): 2402 - 2412. [Abstract] [Full Text] [PDF] A. M. van Rij, G. T. Jones, B. G. Hill, M. Amer, I. A. Thomson, R. A. Pettigrew, and S. G.K. Packer Mechanical Inhibition of Angiogenesis at the Saphenofemoral Junction in the Surgical Treatment of Varicose Veins: Early Results of a Blinded Randomized Controlled Trial Circulation, July 1, 2008; 118(1): 66 - 74. [Abstract] [Full Text] [PDF] T. J. Povsic and P. J. Goldschmidt-Clermont Review: Endothelial progenitor cells: markers of vascular reparative capacity Therapeutic Advances in Cardiovascular Disease, June 1, 2008; 2(3): 199 - 213. [Abstract] [PDF] Z. Sun, J. Wu, H. Fujii, J. Wu, S.-H. Li, S. Porozov, A. Belleli, V. Fulga, Y. Porat, and R.-K. Li Human angiogenic cell precursors restore function in the infarcted rat heart: A comparison of cell delivery routes Eur J Heart Fail, June 1, 2008; 10(6): 525 - 533. [Abstract] [Full Text] [PDF] R. Hinkel, C. El-Aouni, T. Olson, J. Horstkotte, S. Mayer, S. Muller;, M. Willhauck, C. Spitzweg, F.-J. Gildehaus, W. Munzing, et al. Thymosin {beta}4 Is an Essential Paracrine Factor of Embryonic Endothelial Progenitor Cell-Mediated Cardioprotection Circulation, April 29, 2008; 117(17): 2232 - 2240. [Abstract] [Full Text] [PDF] E. Chavakis, G. Carmona, C. Urbich, S. Gottig, R. Henschler, J. M. Penninger, A. M. Zeiher, T. Chavakis, and S. Dimmeler Phosphatidylinositol-3-Kinase-{gamma} Is Integral to Homing Functions of Progenitor Cells Circ. Res., April 25, 2008; 102(8): 942 - 949. [Abstract] [Full Text] [PDF] G. Yao, Z.-H. Liu, C. Zheng, X. Zhang, H. Chen, C. Zeng, and L.-S. Li Evaluation of renal vascular lesions using circulating endothelial cells in patients with lupus nephritis Rheumatology, April 1, 2008; 47(4): 432 - 436. [Abstract] [Full Text] [PDF] G. Carmona, E. Chavakis, U. Koehl, A. M. Zeiher, and S. Dimmeler Activation of Epac stimulates integrin-dependent homing of progenitor cells Blood, March 1, 2008; 111(5): 2640 - 2646. [Abstract] [Full Text] [PDF] D. C. Rafii, B. Psaila, J. Butler, D. K. Jin, and D. Lyden Regulation of Vasculogenesis by Platelet-Mediated Recruitment of Bone Marrow-Derived Cells Arterioscler Thromb Vasc Biol, February 1, 2008; 28(2): 217 - 222. [Abstract] [Full Text] [PDF] J. Zoll, V. Fontaine, P. Gourdy, V. Barateau, J. Vilar, A. Leroyer, I. Lopes-Kam, Z. Mallat, J.-F. Arnal, P. Henry, et al. Role of human smooth muscle cell progenitors in atherosclerotic plaque development and composition Cardiovasc Res, February 1, 2008; 77(3): 471 - 480. [Abstract] [Full Text] [PDF] H.-J. Cho, N. Lee, J. Y. Lee, Y. J. Choi, M. Ii, A. Wecker, J.-O. Jeong, C. Curry, G. Qin, and Y.-s. Yoon Role of host tissues for sustained humoral effects after endothelial progenitor cell transplantation into the ischemic heart J. Exp. Med., December 24, 2007; 204(13): 3257 - 3269. [Abstract] [Full Text] [PDF] T. Kanayasu-Toyoda, A. Ishii-Watabe, T. Suzuki, T. Oshizawa, and T. Yamaguchi A New Role of Thrombopoietin Enhancing ex Vivo Expansion of Endothelial Precursor Cells Derived from AC133-positive Cells J. Biol. Chem., November 16, 2007; 282(46): 33507 - 33514. [Abstract] [Full Text] [PDF] J. Tongers and D. W. Losordo Frontiers in Nephrology: The Evolving Therapeutic Applications of Endothelial Progenitor Cells J. Am. Soc. Nephrol., November 1, 2007; 18(11): 2843 - 2852. [Abstract] [Full Text] [PDF] Y. Li, P. Atmaca-Sonmez, C. L. Schanie, S. T. Ildstad, H. J. Kaplan, and V. Enzmann Endogenous Bone Marrow Derived Cells Express Retinal Pigment Epithelium Cell Markers and Migrate to Focal Areas of RPE Damage Invest. Ophthalmol. Vis. Sci., September 1, 2007; 48(9): 4321 - 4327. [Abstract] [Full Text] [PDF] A. D. Hauer, G. H.M. van Puijvelde, N. Peterse, P. de Vos, V. van Weel, E. J.A. van Wanrooij, E. A.L. Biessen, P. H.A. Quax, A. G. Niethammer, R. A. Reisfeld, et al. Vaccination Against VEGFR2 Attenuates Initiation and Progression of Atherosclerosis Arterioscler Thromb Vasc Biol, September 1, 2007; 27(9): 2050 - 2057. [Abstract] [Full Text] [PDF] S. Levenberg, J. Zoldan, Y. Basevitch, and R. Langer Endothelial potential of human embryonic stem cells Blood, August 1, 2007; 110(3): 806 - 814. [Abstract] [Full Text] [PDF] J. Y. Liu, D. D. Swartz, H. F. Peng, S. F. Gugino, J. A. Russell, and S. T. Andreadis Functional tissue-engineered blood vessels from bone marrow progenitor cells Cardiovasc Res, August 1, 2007; 75(3): 618 - 628. [Abstract] [Full Text] [PDF] A. Schmidt, K. Brixius, and W. Bloch Endothelial Precursor Cell Migration During Vasculogenesis Circ. Res., July 20, 2007; 101(2): 125 - 136. [Abstract] [Full Text] [PDF] F. Timmermans, F. Van Hauwermeiren, M. De Smedt, R. Raedt, F. Plasschaert, M. L. De Buyzere, T. C. Gillebert, J. Plum, and B. Vandekerckhove Endothelial Outgrowth Cells Are Not Derived From CD133+ Cells or CD45+ Hematopoietic Precursors Arterioscler Thromb Vasc Biol, July 1, 2007; 27(7): 1572 - 1579. [Abstract] [Full Text] [PDF] M. Nagano, T. Yamashita, H. Hamada, K. Ohneda, K.-i. Kimura, T. Nakagawa, M. Shibuya, H. Yoshikawa, and O. Ohneda Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood Blood, July 1, 2007; 110(1): 151 - 160. [Abstract] [Full Text] [PDF] C. K. Kissel, R. Lehmann, B. Assmus, A. Aicher, J. Honold, U. Fischer-Rasokat, C. Heeschen, I. Spyridopoulos, S. Dimmeler, and A. M. Zeiher Selective Functional Exhaustion of Hematopoietic Progenitor Cells in the Bone Marrow of Patients With Postinfarction Heart Failure J. Am. Coll. Cardiol., June 19, 2007; 49(24): 2341 - 2349. [Abstract] [Full Text] [PDF] R. M Cubbon, A. Rajwani, and S. B Wheatcroft The impact of insulin resistance on endothelial function, progenitor cells and repair Diabetes and Vascular Disease Research, June 1, 2007; 4(2): 103 - 111. [Abstract] [PDF] G. Invernici, C. Emanueli, P. Madeddu, S. Cristini, S. Gadau, A. Benetti, E. Ciusani, G. Stassi, M. Siragusa, R. Nicosia, et al. Human Fetal Aorta Contains Vascular Progenitor Cells Capable of Inducing Vasculogenesis, Angiogenesis, and Myogenesis in Vitro and in a Murine Model of Peripheral Ischemia Am. J. Pathol., June 1, 2007; 170(6): 1879 - 1892. [Abstract] [Full Text] [PDF] J. M. Melero-Martin, Z. A. Khan, A. Picard, X. Wu, S. Paruchuri, and J. Bischoff In vivo vasculogenic potential of human blood-derived endothelial progenitor cells Blood, June 1, 2007; 109(11): 4761 - 4768. [Abstract] [Full Text] [PDF] H.-K. Oh, J.-M. Ha, E. O, B. H. Lee, S. K. Lee, B.-S. Shim, Y.-K. Hong, and Y. A. Joe Tumor Angiogenesis Promoted by Ex vivo Differentiated Endothelial Progenitor Cells Is Effectively Inhibited by an Angiogenesis Inhibitor, TK1-2 Cancer Res., May 15, 2007; 67(10): 4851 - 4859. [Abstract] [Full Text] [PDF] S. Schwartzenberg, V. Deutsch, S. Maysel-Auslender, S. Kissil, G. Keren, and J. George Circulating Apoptotic Progenitor Cells: A Novel Biomarker in Patients With Acute Coronary Syndromes Arterioscler Thromb Vasc Biol, May 1, 2007; 27(5): e27 - e31. [Abstract] [Full Text] [PDF] V. L.T. Ballard and J. M. Edelberg Stem Cells and the Regeneration of the Aging Cardiovascular System Circ. Res., April 27, 2007; 100(8): 1116 - 1127. [Abstract] [Full Text] [PDF] S. Caballero, N. Sengupta, A. Afzal, K.-H. Chang, S. Li Calzi, D. L. Guberski, T. S. Kern, and M. B. Grant Ischemic Vascular Damage Can Be Repaired by Healthy, but Not Diabetic, Endothelial Progenitor Cells Diabetes, April 1, 2007; 56(4): 960 - 967. [Abstract] [Full Text] [PDF] M. Sigler and C. Jux Biocompatibility of septal defect closure devices Heart, April 1, 2007; 93(4): 444 - 449. [Abstract] [Full Text] [PDF] H. Murata, A. Janin, C. Leboeuf, J. Soulier, E. Gluckman, V. Meignin, and G. Socie Donor-derived cells and human graft-versus-host disease of the skin Blood, March 15, 2007; 109(6): 2663 - 2665. [Abstract] [Full Text] [PDF] A. Aicher, M. Rentsch, K.-i. Sasaki, J. W. Ellwart, F. Fandrich, R. Siebert, J. P. Cooke, S. Dimmeler, and C. Heeschen Nonbone Marrow-Derived Circulating Progenitor Cells Contribute to Postnatal Neovascularization Following Tissue Ischemia Circ. Res., March 2, 2007; 100(4): 581 - 589. [Abstract] [Full Text] [PDF] B. Zhou, F. X. Ma, P. X. Liu, Z. H. Fang, S. L. Wang, Z. B. Han, M.-C. Poon, and Z. C. Han Impaired therapeutic vasculogenesis by transplantation of OxLDL-treated endothelial progenitor cells J. Lipid Res., March 1, 2007; 48(3): 518 - 527. [Abstract] [Full Text] [PDF] Y. Nishiwaki, M. Yoshida, H. Iwaguro, H. Masuda, N. Nitta, T. Asahara, and M. Isobe Endothelial E-Selectin Potentiates Neovascularization via Endothelial Progenitor Cell-Dependent and -Independent Mechanisms Arterioscler Thromb Vasc Biol, March 1, 2007; 27(3): 512 - 518. [Abstract] [Full Text] [PDF] E. Chavakis, A. Hain, M. Vinci, G. Carmona, M. E. Bianchi, P. Vajkoczy, A. M. Zeiher, T. Chavakis, and S. Dimmeler High-Mobility Group Box 1 Activates Integrin-Dependent Homing of Endothelial Progenitor Cells Circ. Res., February 2, 2007; 100(2): 204 - 212. [Abstract] [Full Text] [PDF] M. Sahara, M. Sata, T. Morita, K. Nakamura, Y. Hirata, and R. Nagai Diverse Contribution of Bone Marrow Derived Cells to Vascular Remodeling Associated With Pulmonary Arterial Hypertension and Arterial Neointimal Formation Circulation, January 30, 2007; 115(4): 509 - 517. [Abstract] [Full Text] [PDF] A. O Robb, N. L Mills, D. E Newby, and F. C Denison Endothelial progenitor cells in pregnancy Reproduction, January 1, 2007; 133(1): 1 - 9. [Abstract] [Full Text] [PDF] G. C. Schatteman, M. Dunnwald, and C. Jiao Biology of bone marrow-derived endothelial cell precursors Am J Physiol Heart Circ Physiol, January 1, 2007; 292(1): H1 - H18. [Abstract] [Full Text] [PDF] C. Heeschen, E. Chang, A. Aicher, and J. P. Cooke Endothelial Progenitor Cells Participate in Nicotine-Mediated Angiogenesis J. Am. Coll. Cardiol., December 19, 2006; 48(12): 2553 - 2560. [Abstract] [Full Text] [PDF] K. Miyamoto, K. Nishigami, N. Nagaya, K. Akutsu, M. Chiku, M. Kamei, T. Soma, S. Miyata, M. Higashi, R. Tanaka, et al. Unblinded Pilot Study of Autologous Transplantation of Bone Marrow Mononuclear Cells in Patients With Thromboangiitis Obliterans Circulation, December 12, 2006; 114(24): 2679 - 2684. [Abstract] [Full Text] [PDF] N. Bonaros, R. Rauf, D. Wolf, E. Margreiter, A. Tzankov, B. Schlechta, A. Kocher, H. Ott, T. Schachner, S. Hering, et al. Combined transplantation of skeletal myoblasts and angiopoietic progenitor cells reduces infarct size and apoptosis and improves cardiac function in chronic ischemic heart failure J. Thorac. Cardiovasc. Surg., December 1, 2006; 132(6): 1321 - 1328. [Abstract] [Full Text] [PDF] H. Hamada, M. K. Kim, A. Iwakura, M. Ii, T. Thorne, G. Qin, J. Asai, Y. Tsutsumi, H. Sekiguchi, M. Silver, et al. Estrogen Receptors {alpha} and {beta} Mediate Contribution of Bone Marrow-Derived Endothelial Progenitor Cells to Functional Recovery After Myocardial Infarction Circulation, November 21, 2006; 114(21): 2261 - 2270. [Abstract] [Full Text] [PDF] H. Guven, R. M. Shepherd, R. G. Bach, B. J. Capoccia, and D. C. Link The Number of Endothelial Progenitor Cell Colonies in the Blood Is Increased in Patients With Angiographically Significant Coronary Artery Disease J. Am. Coll. Cardiol., October 17, 2006; 48(8): 1579 - 1587. [Abstract] [Full Text] [PDF] K.-L. Ang, L. Takura Shenje, L. Srinivasan, and M. Galinanes Repair of the damaged heart by bone marrow cells: from experimental evidence to clinical hope. Ann. Thorac. Surg., October 1, 2006; 82(4): 1549 - 1558. [Abstract] [Full Text] [PDF] B. J. Capoccia, R. M. Shepherd, and D. C. Link G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism Blood, October 1, 2006; 108(7): 2438 - 2445. [Abstract] [Full Text] [PDF] M. Aghi, K. S. Cohen, R. J. Klein, D. T. Scadden, and E. A. Chiocca Tumor Stromal-Derived Factor-1 Recruits Vascular Progenitors to Mitotic Neovasculature, where Microenvironment Influences Their Differentiated Phenotypes. Cancer Res., September 15, 2006; 66(18): 9054 - 9064. [Abstract] [Full Text] [PDF] S. Arnhold, P. Heiduschka, H. Klein, Y. Absenger, S. Basnaoglu, F. Kreppel, S. Henke-Fahle, S. Kochanek, K.-U. Bartz-Schmidt, K. Addicks, et al. Adenovirally Transduced Bone Marrow Stromal Cells Differentiate into Pigment Epithelial Cells and Induce Rescue Effects in RCS Rats. Invest. Ophthalmol. Vis. Sci., September 1, 2006; 47(9): 4121 - 4129. [Abstract] [Full Text] [PDF] T. Ishikawa, M. Eguchi, M. Wada, Y. Iwami, K. Tono, H. Iwaguro, H. Masuda, T. Tamaki, and T. Asahara Establishment of a Functionally Active Collagen-Binding Vascular Endothelial Growth Factor Fusion Protein In Situ Arterioscler Thromb Vasc Biol, September 1, 2006; 26(9): 1998 - 2004. [Abstract] [Full Text] [PDF] D. Kaigler, P.H. Krebsbach, Z. Wang, E.R. West, K. Horger, and D.J. Mooney Transplanted Endothelial Cells Enhance Orthotopic Bone Regeneration Journal of Dental Research, July 1, 2006; 85(7): 633 - 637. [Abstract] [Full Text] [PDF] L. Pardanaud and A. Eichmann Identification, emergence and mobilization of circulating endothelial cells or progenitors in the embryo Development, July 1, 2006; 133(13): 2527 - 2537. [Abstract] [Full Text] [PDF] K. Tateno, T. Minamino, H. Toko, H. Akazawa, N. Shimizu, S. Takeda, T. Kunieda, H. Miyauchi, T. Oyama, K. Matsuura, et al. Critical Roles of Muscle-Secreted Angiogenic Factors in Therapeutic Neovascularization Circ. Res., May 12, 2006; 98(9): 1194 - 1202. [Abstract] [Full Text] [PDF] P. Atluri, G. P. Liao, C. M. Panlilio, V. M. Hsu, M. J. Leskowitz, K. J. Morine, J. E. Cohen, M. F. Berry, E. E. Suarez, D. A. Murphy, et al. Neovasculogenic therapy to augment perfusion and preserve viability in ischemic cardiomyopathy. Ann. Thorac. Surg., May 1, 2006; 81(5): 1728 - 1736. [Abstract] [Full Text] [PDF] E. E. Sharpe III, A. A. Teleron, B. Li, J. Price, M. S. Sands, K. Alford, and P. P. Young The Origin and in Vivo Significance of Murine and Human Culture-Expanded Endothelial Progenitor Cells Am. J. Pathol., May 1, 2006; 168(5): 1710 - 1721. [Abstract] [Full Text] [PDF] N. Kogata, Y. Arai, J. T. Pearson, K. Hashimoto, K. Hidaka, T. Koyama, S. Somekawa, Y. Nakaoka, M. Ogawa, R. H. Adams, et al. Cardiac Ischemia Activates Vascular Endothelial Cadherin Promoter in Both Preexisting Vascular Cells and Bone Marrow Cells Involved in Neovascularization Circ. Res., April 14, 2006; 98(7): 897 - 904. [Abstract] [Full Text] [PDF] S Enomoto, M Yoshiyama, T Omura, R Matsumoto, T Kusuyama, D Nishiya, Y Izumi, K Akioka, H Iwao, K Takeuchi, et al. Microbubble destruction with ultrasound augments neovascularisation by bone marrow cell transplantation in rat hind limb ischaemia Heart, April 1, 2006; 92(4): 515 - 520. [Abstract] [Full Text] [PDF] S. Rafii and D. Lyden Contribution of Hematopoietic and Vascular Progenitor Cells to the Neoangiogenic Niche Am. Assoc. Cancer Res. Educ. Book, April 1, 2006; 2006(1): 181 - 185. [Full Text] [PDF] A. Iwakura, S. Shastry, C. Luedemann, H. Hamada, A. Kawamoto, R. Kishore, Y. Zhu, G. Qin, M. Silver, T. Thorne, et al. Estradiol Enhances Recovery After Myocardial Infarction by Augmenting Incorporation of Bone Marrow-Derived Endothelial Progenitor Cells Into Sites of Ischemia-Induced Neovascularization via Endothelial Nitric Oxide Synthase-Mediated Activation of Matrix Metalloproteinase-9 Circulation, March 28, 2006; 113(12): 1605 - 1614. [Abstract] [Full Text] [PDF] M. Ii, H. Takenaka, J. Asai, K. Ibusuki, Y. Mizukami, K. Maruyama, Y.-s. Yoon, A. Wecker, C. Luedemann, E. Eaton, et al. Endothelial Progenitor Thrombospondin-1 Mediates Diabetes-Induced Delay in Reendothelialization Following Arterial Injury Circ. Res., March 17, 2006; 98(5): 697 - 704. [Abstract] [Full Text] [PDF] D. A. Hess, L. Wirthlin, T. P. Craft, P. E. Herrbrich, S. A. Hohm, R. Lahey, W. C. Eades, M. H. Creer, and J. A. Nolta Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells Blood, March 1, 2006; 107(5): 2162 - 2169. [Abstract] [Full Text] [PDF] E. B. Friedrich, K. Walenta, J. Scharlau, G. Nickenig, and N. Werner CD34-/CD133+/VEGFR-2+ Endothelial Progenitor Cell Subpopulation With Potent Vasoregenerative Capacities Circ. Res., February 17, 2006; 98(3): e20 - e25. [Abstract] [Full Text] [PDF] G. Galasso, S. Schiekofer, K. Sato, R. Shibata, D. E. Handy, N. Ouchi, J. A. Leopold, J. Loscalzo, and K. Walsh Impaired Angiogenesis in Glutathione Peroxidase-1-Deficient Mice Is Associated With Endothelial Progenitor Cell Dysfunction Circ. Res., February 3, 2006; 98(2): 254 - 261. [Abstract] [Full Text] [PDF] J. Glod, D. Kobiler, M. Noel, R. Koneru, S. Lehrer, D. Medina, D. Maric, and H. A. Fine Monocytes form a vascular barrier and participate in vessel repair after brain injury Blood, February 1, 2006; 107(3): 940 - 946. [Abstract] [Full Text] [PDF] V. N. Lama and S. H. Phan The extrapulmonary origin of fibroblasts: stem/progenitor cells and beyond. Proceedings of the ATS, January 1, 2006; 3(4): 373 - 376. [Abstract] [Full Text] [PDF] V. L. Ballard and J. M. Edelberg Harnessing Hormonal Signaling for Cardioprotection Sci. Aging Knowl. Environ., December 21, 2005; 2005(51): re6 - re6. [Abstract] [Full Text] [PDF] A. N. Patel, L. Geffner, R. F. Vina, J. Saslavsky, H. C. Urschel Jr, R. Kormos, and F. Benetti Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: A prospective randomized study J. Thorac. Cardiovasc. Surg., December 1, 2005; 130(6): 1631 - 1638. [Abstract] [Full Text] [PDF] D. H. Walter, J. Haendeler, J. Reinhold, U. Rochwalsky, F. Seeger, J. Honold, J. Hoffmann, C. Urbich, R. Lehmann, F. Arenzana-Seisdesdos, et al. Impaired CXCR4 Signaling Contributes to the Reduced Neovascularization Capacity of Endothelial Progenitor Cells From Patients With Coronary Artery Disease Circ. Res., November 25, 2005; 97(11): 1142 - 1151. [Abstract] [Full Text] [PDF]

	Copyright © 1998 by American Society of Hematology         Online ISSN: 1528-0020