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Evidence for Circulating Bone Marrow-Derived Endothelial Cells
Qun Shi,
Shahin Rafii,
Moses Hong-De Wu,
Errol S. Wijelath,
Cong Yu,
Atsushi Ishida,
Yuji Fujita,
Sudesh Kothari,
Robert Mohle,
Lester R. Sauvage,
Malcom A.S. Moore,
Rainer F. Storb, and
William
P. Hammond
From the Departments of Surgery and Molecular Biology, The Hope Heart
Institute and Providence Medical Center, Seattle, WA; the
Hematology-Oncology Division, Cornell Medical College, New York, NY;
the Fred Hutchinson Cancer Research Center, Seattle, WA; the
Sloan-Kettering Cancer Research Center, New York, NY; and the
Departments of Surgery and Medicine, University of Washington School of
Medicine, Seattle, WA.
It has been proposed that hematopoietic and endothelial cells are
derived from a common cell, the hemangioblast. In this study, we
demonstrate that a subset of CD34+ cells have the
capacity to differentiate into endothelial cells in vitro in the
presence of basic fibroblast growth factor, insulin-like growth
factor-1, and vascular endothelial growth factor. These differentiated
endothelial cells are CD34+, stain for von Willebrand
factor (vWF), and incorporate acetylated low-density lipoprotein
(LDL). This suggests the possible existence of a bone
marrow-derived precursor endothelial cell. To demonstrate this
phenomenon in vivo, we used a canine bone marrow transplantation model,
in which the marrow cells from the donor and recipient are genetically
distinct. Between 6 to 8 months after transplantation, a Dacron graft,
made impervious to prevent capillary ingrowth from the surrounding
perigraft tissue, was implanted in the descending thoracic aorta. After
12 weeks, the graft was retrieved, and cells with endothelial
morphology were identified by silver nitrate staining. Using the
di(CA)n and tetranucleotide (GAAA)n repeat polymorphisms to distinguish between the donor and recipient DNA, we
observed that only donor alleles were detected in DNA from positively
stained cells on the impervious Dacron graft. These results strongly
suggest that a subset of CD34+ cells localized in the
bone marrow can be mobilized to the peripheral circulation and can
colonize endothelial flow surfaces of vascular prostheses.
Blood, Vol. 92 No. 2 (July 15), 1998:
pp. 362-367
© 1998 by the American Society of Hematology.

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|
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|
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|
 |
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|
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|
 |
|

|
 |

|
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|
 |
|

|
 |

|
 |
 
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22(9):
3234 - 3246.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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28(9):
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[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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57(9):
2402 - 2412.
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|
 |
|

|
 |

|
 |
 
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July 1, 2008;
118(1):
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[Abstract]
[Full Text]
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|
 |
|

|
 |

|
 |
 
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2(3):
199 - 213.
[Abstract]
[PDF]
|
 |
|

|
 |

|
 |
 
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June 1, 2008;
10(6):
525 - 533.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
R. Hinkel, C. El-Aouni, T. Olson, J. Horstkotte, S. Mayer, S. Muller;, M. Willhauck, C. Spitzweg, F.-J. Gildehaus, W. Munzing, et al.
Thymosin {beta}4 Is an Essential Paracrine Factor of Embryonic Endothelial Progenitor Cell-Mediated Cardioprotection
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117(17):
2232 - 2240.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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April 25, 2008;
102(8):
942 - 949.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
G. Yao, Z.-H. Liu, C. Zheng, X. Zhang, H. Chen, C. Zeng, and L.-S. Li
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April 1, 2008;
47(4):
432 - 436.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
G. Carmona, E. Chavakis, U. Koehl, A. M. Zeiher, and S. Dimmeler
Activation of Epac stimulates integrin-dependent homing of progenitor cells
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March 1, 2008;
111(5):
2640 - 2646.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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February 1, 2008;
28(2):
217 - 222.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. Zoll, V. Fontaine, P. Gourdy, V. Barateau, J. Vilar, A. Leroyer, I. Lopes-Kam, Z. Mallat, J.-F. Arnal, P. Henry, et al.
Role of human smooth muscle cell progenitors in atherosclerotic plaque development and composition
Cardiovasc Res,
February 1, 2008;
77(3):
471 - 480.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
H.-J. Cho, N. Lee, J. Y. Lee, Y. J. Choi, M. Ii, A. Wecker, J.-O. Jeong, C. Curry, G. Qin, and Y.-s. Yoon
Role of host tissues for sustained humoral effects after endothelial progenitor cell transplantation into the ischemic heart
J. Exp. Med.,
December 24, 2007;
204(13):
3257 - 3269.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
T. Kanayasu-Toyoda, A. Ishii-Watabe, T. Suzuki, T. Oshizawa, and T. Yamaguchi
A New Role of Thrombopoietin Enhancing ex Vivo Expansion of Endothelial Precursor Cells Derived from AC133-positive Cells
J. Biol. Chem.,
November 16, 2007;
282(46):
33507 - 33514.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. Tongers and D. W. Losordo
Frontiers in Nephrology: The Evolving Therapeutic Applications of Endothelial Progenitor Cells
J. Am. Soc. Nephrol.,
November 1, 2007;
18(11):
2843 - 2852.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
Y. Li, P. Atmaca-Sonmez, C. L. Schanie, S. T. Ildstad, H. J. Kaplan, and V. Enzmann
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48(9):
4321 - 4327.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Vaccination Against VEGFR2 Attenuates Initiation and Progression of Atherosclerosis
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September 1, 2007;
27(9):
2050 - 2057.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. Levenberg, J. Zoldan, Y. Basevitch, and R. Langer
Endothelial potential of human embryonic stem cells
Blood,
August 1, 2007;
110(3):
806 - 814.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. Y. Liu, D. D. Swartz, H. F. Peng, S. F. Gugino, J. A. Russell, and S. T. Andreadis
Functional tissue-engineered blood vessels from bone marrow progenitor cells
Cardiovasc Res,
August 1, 2007;
75(3):
618 - 628.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Schmidt, K. Brixius, and W. Bloch
Endothelial Precursor Cell Migration During Vasculogenesis
Circ. Res.,
July 20, 2007;
101(2):
125 - 136.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Endothelial Outgrowth Cells Are Not Derived From CD133+ Cells or CD45+ Hematopoietic Precursors
Arterioscler Thromb Vasc Biol,
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27(7):
1572 - 1579.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood
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July 1, 2007;
110(1):
151 - 160.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Selective Functional Exhaustion of Hematopoietic Progenitor Cells in the Bone Marrow of Patients With Postinfarction Heart Failure
J. Am. Coll. Cardiol.,
June 19, 2007;
49(24):
2341 - 2349.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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The impact of insulin resistance on endothelial function, progenitor cells and repair
Diabetes and Vascular Disease Research,
June 1, 2007;
4(2):
103 - 111.
[Abstract]
[PDF]
|
 |
|

|
 |

|
 |
 
G. Invernici, C. Emanueli, P. Madeddu, S. Cristini, S. Gadau, A. Benetti, E. Ciusani, G. Stassi, M. Siragusa, R. Nicosia, et al.
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Am. J. Pathol.,
June 1, 2007;
170(6):
1879 - 1892.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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In vivo vasculogenic potential of human blood-derived endothelial progenitor cells
Blood,
June 1, 2007;
109(11):
4761 - 4768.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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Tumor Angiogenesis Promoted by Ex vivo Differentiated Endothelial Progenitor Cells Is Effectively Inhibited by an Angiogenesis Inhibitor, TK1-2
Cancer Res.,
May 15, 2007;
67(10):
4851 - 4859.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
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27(5):
e27 - e31.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
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|
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April 27, 2007;
100(8):
1116 - 1127.
[Abstract]
[Full Text]
[PDF]
|
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|

|
 |

|
 |
 
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April 1, 2007;
56(4):
960 - 967.
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|
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|
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|
 |
 
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93(4):
444 - 449.
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|
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|
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|
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2663 - 2665.
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|
 |
 
B. Zhou, F. X. Ma, P. X. Liu, Z. H. Fang, S. L. Wang, Z. B. Han, M.-C. Poon, and Z. C. Han
Impaired therapeutic vasculogenesis by transplantation of OxLDL-treated endothelial progenitor cells
J. Lipid Res.,
March 1, 2007;
48(3):
518 - 527.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
Y. Nishiwaki, M. Yoshida, H. Iwaguro, H. Masuda, N. Nitta, T. Asahara, and M. Isobe
Endothelial E-Selectin Potentiates Neovascularization via Endothelial Progenitor Cell-Dependent and -Independent Mechanisms
Arterioscler Thromb Vasc Biol,
March 1, 2007;
27(3):
512 - 518.
[Abstract]
[Full Text]
[PDF]
|
 |
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|
 |

|
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E. Chavakis, A. Hain, M. Vinci, G. Carmona, M. E. Bianchi, P. Vajkoczy, A. M. Zeiher, T. Chavakis, and S. Dimmeler
High-Mobility Group Box 1 Activates Integrin-Dependent Homing of Endothelial Progenitor Cells
Circ. Res.,
February 2, 2007;
100(2):
204 - 212.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Sahara, M. Sata, T. Morita, K. Nakamura, Y. Hirata, and R. Nagai
Diverse Contribution of Bone Marrow Derived Cells to Vascular Remodeling Associated With Pulmonary Arterial Hypertension and Arterial Neointimal Formation
Circulation,
January 30, 2007;
115(4):
509 - 517.
[Abstract]
[Full Text]
[PDF]
|
 |
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|
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|
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A. O Robb, N. L Mills, D. E Newby, and F. C Denison
Endothelial progenitor cells in pregnancy
Reproduction,
January 1, 2007;
133(1):
1 - 9.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
G. C. Schatteman, M. Dunnwald, and C. Jiao
Biology of bone marrow-derived endothelial cell precursors
Am J Physiol Heart Circ Physiol,
January 1, 2007;
292(1):
H1 - H18.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. Heeschen, E. Chang, A. Aicher, and J. P. Cooke
Endothelial Progenitor Cells Participate in Nicotine-Mediated Angiogenesis
J. Am. Coll. Cardiol.,
December 19, 2006;
48(12):
2553 - 2560.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
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K. Miyamoto, K. Nishigami, N. Nagaya, K. Akutsu, M. Chiku, M. Kamei, T. Soma, S. Miyata, M. Higashi, R. Tanaka, et al.
Unblinded Pilot Study of Autologous Transplantation of Bone Marrow Mononuclear Cells in Patients With Thromboangiitis Obliterans
Circulation,
December 12, 2006;
114(24):
2679 - 2684.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
N. Bonaros, R. Rauf, D. Wolf, E. Margreiter, A. Tzankov, B. Schlechta, A. Kocher, H. Ott, T. Schachner, S. Hering, et al.
Combined transplantation of skeletal myoblasts and angiopoietic progenitor cells reduces infarct size and apoptosis and improves cardiac function in chronic ischemic heart failure
J. Thorac. Cardiovasc. Surg.,
December 1, 2006;
132(6):
1321 - 1328.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
H. Hamada, M. K. Kim, A. Iwakura, M. Ii, T. Thorne, G. Qin, J. Asai, Y. Tsutsumi, H. Sekiguchi, M. Silver, et al.
Estrogen Receptors {alpha} and {beta} Mediate Contribution of Bone Marrow-Derived Endothelial Progenitor Cells to Functional Recovery After Myocardial Infarction
Circulation,
November 21, 2006;
114(21):
2261 - 2270.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
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|
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H. Guven, R. M. Shepherd, R. G. Bach, B. J. Capoccia, and D. C. Link
The Number of Endothelial Progenitor Cell Colonies in the Blood Is Increased in Patients With Angiographically Significant Coronary Artery Disease
J. Am. Coll. Cardiol.,
October 17, 2006;
48(8):
1579 - 1587.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K.-L. Ang, L. Takura Shenje, L. Srinivasan, and M. Galinanes
Repair of the damaged heart by bone marrow cells: from experimental evidence to clinical hope.
Ann. Thorac. Surg.,
October 1, 2006;
82(4):
1549 - 1558.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
B. J. Capoccia, R. M. Shepherd, and D. C. Link
G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism
Blood,
October 1, 2006;
108(7):
2438 - 2445.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
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|
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M. Aghi, K. S. Cohen, R. J. Klein, D. T. Scadden, and E. A. Chiocca
Tumor Stromal-Derived Factor-1 Recruits Vascular Progenitors to Mitotic Neovasculature, where Microenvironment Influences Their Differentiated Phenotypes.
Cancer Res.,
September 15, 2006;
66(18):
9054 - 9064.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. Arnhold, P. Heiduschka, H. Klein, Y. Absenger, S. Basnaoglu, F. Kreppel, S. Henke-Fahle, S. Kochanek, K.-U. Bartz-Schmidt, K. Addicks, et al.
Adenovirally Transduced Bone Marrow Stromal Cells Differentiate into Pigment Epithelial Cells and Induce Rescue Effects in RCS Rats.
Invest. Ophthalmol. Vis. Sci.,
September 1, 2006;
47(9):
4121 - 4129.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
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T. Ishikawa, M. Eguchi, M. Wada, Y. Iwami, K. Tono, H. Iwaguro, H. Masuda, T. Tamaki, and T. Asahara
Establishment of a Functionally Active Collagen-Binding Vascular Endothelial Growth Factor Fusion Protein In Situ
Arterioscler Thromb Vasc Biol,
September 1, 2006;
26(9):
1998 - 2004.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
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|
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D. Kaigler, P.H. Krebsbach, Z. Wang, E.R. West, K. Horger, and D.J. Mooney
Transplanted Endothelial Cells Enhance Orthotopic Bone Regeneration
Journal of Dental Research,
July 1, 2006;
85(7):
633 - 637.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
L. Pardanaud and A. Eichmann
Identification, emergence and mobilization of circulating endothelial cells or progenitors in the embryo
Development,
July 1, 2006;
133(13):
2527 - 2537.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K. Tateno, T. Minamino, H. Toko, H. Akazawa, N. Shimizu, S. Takeda, T. Kunieda, H. Miyauchi, T. Oyama, K. Matsuura, et al.
Critical Roles of Muscle-Secreted Angiogenic Factors in Therapeutic Neovascularization
Circ. Res.,
May 12, 2006;
98(9):
1194 - 1202.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
P. Atluri, G. P. Liao, C. M. Panlilio, V. M. Hsu, M. J. Leskowitz, K. J. Morine, J. E. Cohen, M. F. Berry, E. E. Suarez, D. A. Murphy, et al.
Neovasculogenic therapy to augment perfusion and preserve viability in ischemic cardiomyopathy.
Ann. Thorac. Surg.,
May 1, 2006;
81(5):
1728 - 1736.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
E. E. Sharpe III, A. A. Teleron, B. Li, J. Price, M. S. Sands, K. Alford, and P. P. Young
The Origin and in Vivo Significance of Murine and Human Culture-Expanded Endothelial Progenitor Cells
Am. J. Pathol.,
May 1, 2006;
168(5):
1710 - 1721.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
N. Kogata, Y. Arai, J. T. Pearson, K. Hashimoto, K. Hidaka, T. Koyama, S. Somekawa, Y. Nakaoka, M. Ogawa, R. H. Adams, et al.
Cardiac Ischemia Activates Vascular Endothelial Cadherin Promoter in Both Preexisting Vascular Cells and Bone Marrow Cells Involved in Neovascularization
Circ. Res.,
April 14, 2006;
98(7):
897 - 904.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S Enomoto, M Yoshiyama, T Omura, R Matsumoto, T Kusuyama, D Nishiya, Y Izumi, K Akioka, H Iwao, K Takeuchi, et al.
Microbubble destruction with ultrasound augments neovascularisation by bone marrow cell transplantation in rat hind limb ischaemia
Heart,
April 1, 2006;
92(4):
515 - 520.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
S. Rafii and D. Lyden
Contribution of Hematopoietic and Vascular Progenitor Cells to the Neoangiogenic Niche
Am. Assoc. Cancer Res. Educ. Book,
April 1, 2006;
2006(1):
181 - 185.
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. Iwakura, S. Shastry, C. Luedemann, H. Hamada, A. Kawamoto, R. Kishore, Y. Zhu, G. Qin, M. Silver, T. Thorne, et al.
Estradiol Enhances Recovery After Myocardial Infarction by Augmenting Incorporation of Bone Marrow-Derived Endothelial Progenitor Cells Into Sites of Ischemia-Induced Neovascularization via Endothelial Nitric Oxide Synthase-Mediated Activation of Matrix Metalloproteinase-9
Circulation,
March 28, 2006;
113(12):
1605 - 1614.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. Ii, H. Takenaka, J. Asai, K. Ibusuki, Y. Mizukami, K. Maruyama, Y.-s. Yoon, A. Wecker, C. Luedemann, E. Eaton, et al.
Endothelial Progenitor Thrombospondin-1 Mediates Diabetes-Induced Delay in Reendothelialization Following Arterial Injury
Circ. Res.,
March 17, 2006;
98(5):
697 - 704.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. A. Hess, L. Wirthlin, T. P. Craft, P. E. Herrbrich, S. A. Hohm, R. Lahey, W. C. Eades, M. H. Creer, and J. A. Nolta
Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells
Blood,
March 1, 2006;
107(5):
2162 - 2169.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
E. B. Friedrich, K. Walenta, J. Scharlau, G. Nickenig, and N. Werner
CD34-/CD133+/VEGFR-2+ Endothelial Progenitor Cell Subpopulation With Potent Vasoregenerative Capacities
Circ. Res.,
February 17, 2006;
98(3):
e20 - e25.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
G. Galasso, S. Schiekofer, K. Sato, R. Shibata, D. E. Handy, N. Ouchi, J. A. Leopold, J. Loscalzo, and K. Walsh
Impaired Angiogenesis in Glutathione Peroxidase-1-Deficient Mice Is Associated With Endothelial Progenitor Cell Dysfunction
Circ. Res.,
February 3, 2006;
98(2):
254 - 261.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. Glod, D. Kobiler, M. Noel, R. Koneru, S. Lehrer, D. Medina, D. Maric, and H. A. Fine
Monocytes form a vascular barrier and participate in vessel repair after brain injury
Blood,
February 1, 2006;
107(3):
940 - 946.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
V. N. Lama and S. H. Phan
The extrapulmonary origin of fibroblasts: stem/progenitor cells and beyond.
Proceedings of the ATS,
January 1, 2006;
3(4):
373 - 376.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
V. L. Ballard and J. M. Edelberg
Harnessing Hormonal Signaling for Cardioprotection
Sci. Aging Knowl. Environ.,
December 21, 2005;
2005(51):
re6 - re6.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
A. N. Patel, L. Geffner, R. F. Vina, J. Saslavsky, H. C. Urschel Jr, R. Kormos, and F. Benetti
Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: A prospective randomized study
J. Thorac. Cardiovasc. Surg.,
December 1, 2005;
130(6):
1631 - 1638.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
D. H. Walter, J. Haendeler, J. Reinhold, U. Rochwalsky, F. Seeger, J. Honold, J. Hoffmann, C. Urbich, R. Lehmann, F. Arenzana-Seisdesdos, et al.
Impaired CXCR4 Signaling Contributes to the Reduced Neovascularization Capacity of Endothelial Progenitor Cells From Patients With Coronary Artery Disease
Circ. Res.,
November 25, 2005;
97(11):
1142 - 1151.
[Abstract]
[Full Text]
[PDF]
|
 |
|
|
|