Blood, Vol. 94 No. 10 (November 15), 1999:
pp. 3365-3365
PHOTOGRAPH

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Early erythroblastic leukemia. This leukemic blast cell displays
typical ultrastructure. The nucleus contains mainly euchromatin and
prominent nucleolus structures. Characteristic granules called granules ( ) because they resemble the greek letter theta and
ferritin containing granules (F) are present in the juxta-nuclear
region near the centriole (c). Large size mitochondria (m) and lipid
inclusions (L) are frequent (original magnification ×18,000). (Inset)
High magnification of the characteristic granule ultrastructure.
Ferritin molecules are identified in the granules by their density and
shape (F). granules exhibit complex internal structures (original
magnification ×54,600). (Courtesy of Elisabeth M. Cramer, MD, PhD,
INSERM U. 474, Hopital Henri Mondor, 51 av. du Marechal de
Lattre-de-Tassigny, Creteil 94010, France.)
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