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Blood, 15 October 2000, Vol. 96, No. 8, pp. 2682-2690
CHEMOKINES
Presentation of chemokine SDF-1 by fibronectin mediates
directed migration of T cells
Anthony J. Pelletier,
Luc
J. W. van der Laan,
Patrick Hildbrand,
Michael A. Siani,
Darren A. Thompson,
Philip E. Dawson,
Bruce E. Torbett, and
Daniel R. Salomon
From the Departments of Molecular and Experimental
Medicine and Chemistry, The Scripps Research Institute, La Jolla; and
Gryphon Sciences, San Francisco, CA.
The role of chemokine-matrix interactions in integrin-dependent
T-cell migration was examined to address the critical question of how
chemokines provide directional information. The chemokine SDF-1
binds fibronectin (Fn) with a low nanomolar Kd
(equilibrium dissociation constant). SDF-1 presented by Fn induced
directed migration. Spatial concentration gradients of chemokine were
not required to maintain directed migration. Fn-presented chemokine induced the polarization of cells, including the redistribution of the
SDF-1 receptor, to the basal surface and leading edge of the cell. A
new model for directed migration is proposed in which the
co-presentation of an adhesive matrix and chemokine provides the
necessary positional information independent of a soluble spatial gradient.
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[Abstract]
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|
|
|
|
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|
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August 14, 2001;
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9642 - 9647.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
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