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 Blood, 1 September 2006, Vol. 108, No. 5, pp. 1451-1460.
Prepublished online as a Blood First Edition Paper on April 25, 2006; DOI 10.1182/blood-2006-02-005017.

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Submitted February 21, 2006
Accepted April 16, 2006

Ocular adnexal lymphoma: a review of clinicopathologic features and treatment options

Didier Decaudin*, Patricia de Cremoux, Anne Vincent-Salomon, Remi Dendale, and Livia Lumbroso-Le Rouic

Department of Clinical Hematology / UMR 144 CNRS, Institut Curie
Department of Tumor Biology, Institut Curie
Department of Radiation Oncology, Institut Curie
Department of Ophthalmology, Institut Curie

* Corresponding author; email: didier.decaudin{at}curie.net.

There has been considerable interest, in the recent literature, in ocular adnexal lymphomas and their biological and clinical characteristics with a possible association with Chlamydia psittaci infection, and in their therapeutic management with rituximab or anti-Chlamydia psittaci antibiotic therapy. These new data have modified the previously reported features of this disease and therefore require an updated review of the literature. The aims of this review are to present the current knowledge on the biology of these lymphomas, their clinical features and prognostic factors, and finally the panel of all available treatment options.


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