SEARCH:   Advanced

Blood, 21 May 2009, Vol. 113, No. 21, pp. 5064-5073. Prepublished online as a Blood First Edition Paper on March 11, 2009; DOI 10.1182/blood-2008-10-184168. This Article Full Text (PDF) All Versions of this Article: blood-2008-10-184168v1 113/21/5064    most recent Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Bradford, P. T. Articles by Toro, J. R. Search for Related Content PubMed PubMed Citation Articles by Bradford, P. T. Articles by Toro, J. R. Social Bookmarking                   What's this?  Previous Article  |  Next Article  Submitted October 29, 2008 Accepted March 2, 2009 Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3,884 cases Porcia T. Bradford, Susan S. Devesa, William F. Anderson, and Jorge R. Toro* Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States * Corresponding author; email: toroj{at}mail.nih.gov. There have been no prior large population-based studies focusing on cutaneous lymphomas (CL) in the United States. Using the Surveillance, Epidemiology and End Results (SEER) program, we analyzed age-adjusted CL incidence rates (IR) and survival rates by gender and race/ethnicity. There were 3,884 CLs diagnosed during 2001-2005. Cutaneous T-cell lymphomas (CTCLs) accounted for 71% (IR=7.7/1,000,000 person-years), while cutaneous B-cell lymphomas (CBCLs) accounted for 29% (IR=3.1/1,000,000 person-years). Males had a significant higher IR of CL than females [14.0 vs. 8.2/1,000,000 person-years, respectively; M:F IRR 1.72; p<0.0001]. The M:F IRR ranged between 1.28-2.55 for the various CTCLs and CBCLs. Age-adjusted CL IRs were highest among Non-Hispanic Whites and Blacks (both 11.5/1,000,000 person-years), followed by Hispanic Whites (7.9) and Asian/Pacific Islanders (7.1). The CTCL IR was highest among Blacks (10.0/1,000,000 person-years), while the CBCL IR was highest among Non-Hispanic Whites (3.5). Over the last 25 years, the CL IR increased from 5.0/ 1,000,000 person-years during 1980-1982 to 14.3 during 2001-2003. Then, during 2004-2005 the CL IR was 12.7. Part of this recent apparent change, could be related to incomplete case ascertainment, or potential leveling off of IRs. CLs rates vary markedly by race, gender supporting the notion that they represent distinct disease entities. CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: H. M. Prince, S. Whittaker, and R. T. Hoppe How I treat mycosis fungoides and Sezary syndrome Blood, November 12, 2009; 114(20): 4337 - 4353. [Abstract] [Full Text] [PDF]

	Copyright © 2009 by American Society of Hematology         Online ISSN: 1528-0020