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Receive this page by email each issue: [Sign up for eTOCs] Other Issues: June 1 2007; 109 (11)   [Index by Author]  [Cover Caption]  [Complete Inside Blood PDF]         INSIDE BLOOD        BLOOD WORK        PLENARY PAPERS        REVIEW ARTICLES        HOW I TREAT        CHEMOKINES, CYTOKINES, AND INTERLEUKINS        CLINICAL TRIALS AND OBSERVATIONS        GENE THERAPY        HEMATOPOIESIS        HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY        IMMUNOBIOLOGY        NEOPLASIA        RED CELLS        STEM CELLS IN HEMATOLOGY        TRANSPLANTATION        CORRESPONDENCE        ERRATUM Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: Pumping out platelets Douglas B. Cines Blood 2007 109: 4591-4592. [Full Text] [PDF]   No more transplantation in CML? François Guilhot Blood 2007 109: 4592. [Full Text] [PDF]   PD-1+ T cells: exhausted and premature? Lishan Su Blood 2007 109: 4593-4594. [Full Text] [PDF]   How low can you go: quality effects of an anti-CD4 antibody Ellen J. Kim and Alain H. Rook Blood 2007 109: 4594-4595. [Full Text] [PDF]   Altruistic donor T cells Pierre Tiberghien Blood 2007 109: 4595. [Full Text] [PDF]   Inhibitors in hemophilia: nature or nurture? Thomas Abshire Blood 2007 109: 4596. [Full Text] [PDF]   Trading muscle iron for erythropoiesis at high altitude Chaim Hershko Blood 2007 109: 4597. [Full Text] [PDF]   BLOOD WORK: Adult T-cell leukemia/lymphoma Blood 2007 109: 4598. [Full Text] [PDF]   PLENARY PAPERS: Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival Adrian Wiestner, Mahsa Tehrani, Michael Chiorazzi, George Wright, Federica Gibellini, Kazutaka Nakayama, Hui Liu, Andreas Rosenwald, H. Konrad Muller-Hermelink, German Ott, Wing C. Chan, Timothy C. Greiner, Dennis D. Weisenburger, Julie Vose, James O. Armitage, Randy D. Gascoyne, Joseph M. Connors, Elias Campo, Emilio Montserrat, Francesc Bosch, Erlend B. Smeland, Stein Kvaloy, Harald Holte, Jan Delabie, Richard I. Fisher, Thomas M. Grogan, Thomas P. Miller, Wyndham H. Wilson, Elaine S. Jaffe, and Louis M. Staudt, for the Lymphoma/Leukemia Molecular Profiling Project Blood 2007 109: 4599-4606. Prepublished online February 13, 2007; DOI 10.1182/blood-2006-08-039859 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   REVIEW ARTICLES: New thrombopoietic growth factors David J. Kuter Blood 2007 109: 4607-4616. Prepublished online February 8, 2007; DOI 10.1182/blood-2006-10-019315 [Abstract] [Full Text] [PDF]   HOW I TREAT: How I treat indolent lymphoma John G. Gribben Blood 2007 109: 4617-4626. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-10-041863 [Abstract] [Full Text] [PDF]   CHEMOKINES, CYTOKINES, AND INTERLEUKINS: The peritoneal micromilieu commits B cells to home to body cavities and the small intestine Simon Berberich, Reinhold Förster, and Oliver Pabst Blood 2007 109: 4627-4634. Prepublished online February 8, 2007; DOI 10.1182/blood-2006-12-064345 [Abstract] [Full Text] [PDF]   CLINICAL TRIALS AND OBSERVATIONS: Low-dose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA–positive chronic eosinophilic leukemia Jelena V. Jovanovic, Joannah Score, Katherine Waghorn, Daniela Cilloni, Enrico Gottardi, Georgia Metzgeroth, Philipp Erben, Helena Popp, Christoph Walz, Andreas Hochhaus, Catherine Roche-Lestienne, Claude Preudhomme, Ellen Solomon, Jane Apperley, Michela Rondoni, Emanuela Ottaviani, Giovanni Martinelli, Finella Brito-Babapulle, Giuseppe Saglio, Rüdiger Hehlmann, Nicholas C. P. Cross, Andreas Reiter, and David Grimwade, on behalf of the European LeukemiaNet Blood 2007 109: 4635-4640. Prepublished online February 13, 2007; DOI 10.1182/blood-2006-10-050054 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia: an international retrospective study Henrik Hasle, Todd A. Alonzo, Anne Auvrignon, Catherine Behar, Myron Chang, Ursula Creutzig, Alexandra Fischer, Erik Forestier, Alcira Fynn, Oskar A. Haas, Jochen Harbott, Christine J. Harrison, Nyla A. Heerema, Marry M. van den Heuvel-Eibrink, Gertjan J. L. Kaspers, Franco Locatelli, Peter Noellke, Sophia Polychronopoulou, Yaddanapudi Ravindranath, Bassem Razzouk, Dirk Reinhardt, Natalia N. Savva, Batia Stark, Stefan Suciu, Ichiro Tsukimoto, David K. Webb, Dorora Wojcik, William G. Woods, Martin Zimmermann, Charlotte M. Niemeyer, and Susana C. Raimondi Blood 2007 109: 4641-4647. Prepublished online February 13, 2007; DOI 10.1182/blood-2006-10-051342 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Treatment-related risk factors of inhibitor development in previously untreated patients with hemophilia A: the CANAL cohort study Samantha C. Gouw, Johanna G. van der Bom, and H. Marijke van den Berg, for the CANAL Study group Blood 2007 109: 4648-4654. Prepublished online February 8, 2007; DOI 10.1182/blood-2006-11-056291 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Clinical efficacy of zanolimumab (HuMax-CD4): two phase 2 studies in refractory cutaneous T-cell lymphoma Youn H. Kim, Madeleine Duvic, Erik Obitz, Robert Gniadecki, Lars Iversen, Anders Österborg, Sean Whittaker, Timothy M. Illidge, Thomas Schwarz, Roland Kaufmann, Kevin Cooper, Kim M. Knudsen, Steen Lisby, Ole Baadsgaard, and Susan J. Knox Blood 2007 109: 4655-4662. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-12-062877 [Abstract] [Full Text] [PDF]   Racial variation in the relationship of anemia with mortality and mobility disability among older adults Kushang V. Patel, Tamara B. Harris, Marion Faulhaber, Sara B. Angleman, Stephanie Connelly, Douglas C. Bauer, Lewis H. Kuller, Anne B. Newman, and Jack M. Guralnik, for the Health, Aging, and Body Composition Study Blood 2007 109: 4663-4670. Prepublished online February 6, 2007; DOI 10.1182/blood-2006-10-055384 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors Ji-Yuan Zhang, Zheng Zhang, Xicheng Wang, Jun-Liang Fu, Jinxia Yao, Yanmei Jiao, Liangen Chen, Hui Zhang, Jianan Wei, Lei Jin, Ming Shi, George Fu Gao, Hao Wu, and Fu-Sheng Wang Blood 2007 109: 4671-4678. Prepublished online February 1, 2007; DOI 10.1182/blood-2006-09-044826 [Abstract] [Full Text] [PDF]   Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemia William G. Wierda, Susan O'Brien, Xuemei Wang, Stefan Faderl, Alessandra Ferrajoli, Kim-Anh Do, Jorge Cortes, Deborah Thomas, Guillermo Garcia-Manero, Charles Koller, Miloslav Beran, Francis Giles, Farhad Ravandi, Susan Lerner, Hagop Kantarjian, and Michael Keating Blood 2007 109: 4679-4685. Prepublished online February 13, 2007; DOI 10.1182/blood-2005-12-051458 [Abstract] [Full Text] [PDF]   Drug treatment is superior to allografting as first-line therapy in chronic myeloid leukemia Rüdiger Hehlmann, Ute Berger, Markus Pfirrmann, Hermann Heimpel, Andreas Hochhaus, Joerg Hasford, Hans-Jochem Kolb, Tanja Lahaye, Ole Maywald, Andreas Reiter, Dieter K. Hossfeld, Christoph Huber, Helmut Löffler, Hans Pralle, Wolfgang Queisser, Andreas Tobler, Christoph Nerl, Max Solenthaler, Mariele E. Goebeler, Martin Griesshammer, Thomas Fischer, Stephan Kremers, Hartmut Eimermacher, Michael Pfreundschuh, Wolf-Dietrich Hirschmann, Klaus Lechner, Barbara Wassmann, Christiane Falge, Hartmut H. Kirchner, and Alois Gratwohl, for the Schweizerische Arbeitsgemeinschaft für Klinische Krebsforschung (SAKK) and the German CML Study Group Blood 2007 109: 4686-4692. Prepublished online February 22, 2007; DOI 10.1182/blood-2006-11-055186 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study Samantha C. Gouw, Johanna G. van der Bom, Günter Auerswald, Carmen Escuriola Ettinghausen, Ulf Tedgård, and H. Marijke van den Berg, for the CANAL Study group Blood 2007 109: 4693-4697. Prepublished online January 11, 2007; DOI 10.1182/blood-2006-11-056317 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   GENE THERAPY: Antitumor effects of HSV-TK–engineered donor lymphocytes after allogeneic stem-cell transplantation Fabio Ciceri, Chiara Bonini, Sarah Marktel, Elisabetta Zappone, Paolo Servida, Massimo Bernardi, Alessandra Pescarollo, Attilio Bondanza, Jacopo Peccatori, Silvano Rossini, Zulma Magnani, Monica Salomoni, Claudia Benati, Maurilio Ponzoni, Luciano Callegaro, Paolo Corradini, Marco Bregni, Catia Traversari, and Claudio Bordignon Blood 2007 109: 4698-4707. Prepublished online February 27, 2007; DOI 10.1182/blood-2006-05-023416 [Abstract] [Full Text] [PDF]   The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies Catia Traversari, Sarah Marktel, Zulma Magnani, Patrizia Mangia, Vincenzo Russo, Fabio Ciceri, Chiara Bonini, and Claudio Bordignon Blood 2007 109: 4708-4715. Prepublished online February 27, 2007; DOI 10.1182/blood-2006-04-015230 [Abstract] [Full Text] [PDF]   HEMATOPOIESIS: G-CSF treatment of severe congenital neutropenia reverses neutropenia but does not correct the underlying functional deficiency of the neutrophil in defending against microorganisms Marta Donini, Stefania Fontana, Gianfranco Savoldi, William Vermi, Laura Tassone, Francesca Gentili, Elena Zenaro, Daniela Ferrari, Lucia D. Notarangelo, Fulvio Porta, Fabio Facchetti, Luigi D. Notarangelo, Stefano Dusi, and Raffaele Badolato Blood 2007 109: 4716-4723. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-09-045427 [Abstract] [Full Text] [PDF]   Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle Paul Robach, Gaetano Cairo, Cecilia Gelfi, Francesca Bernuzzi, Henriette Pilegaard, Agnese Viganò, Paolo Santambrogio, Paolo Cerretelli, José A. L. Calbet, Stéphane Moutereau, and Carsten Lundby Blood 2007 109: 4724-4731. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-08-040006 [Abstract] [Full Text] [PDF]   Evidence that the Pim1 kinase gene is a direct target of HOXA9 Yu-Long Hu, Emmanuelle Passegué, Stephen Fong, Corey Largman, and Hugh Jeffrey Lawrence Blood 2007 109: 4732-4738. Prepublished online February 27, 2007; DOI 10.1182/blood-2006-08-043356 [Abstract] [Full Text] [PDF] [Supplemental Methods]   Brief report  Phase 1 clinical study of eltrombopag, an oral, nonpeptide thrombopoietin receptor agonist Julian M. Jenkins, Daphne Williams, Yanli Deng, Joanne Uhl, Valerie Kitchen, David Collins, and Connie L. Erickson-Miller Blood 2007 109: 4739-4741. Prepublished online February 27, 2007; DOI 10.1182/blood-2006-11-057968 [Abstract] [Full Text] [PDF]   HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY: Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure Femke Zwerts, Florea Lupu, Astrid De Vriese, Saskia Pollefeyt, Lieve Moons, Rachel A. Altura, Yuying Jiang, Patrick H. Maxwell, Peter Hill, Hideyasu Oh, Claus Rieker, Désiré Collen, Simon J. Conway, and Edward M. Conway Blood 2007 109: 4742-4752. Prepublished online February 13, 2007; DOI 10.1182/blood-2006-06-028068 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion Jeffrey S. Scehnet, Weidong Jiang, S. Ram Kumar, Valery Krasnoperov, Alexandre Trindade, Rui Benedito, Dusan Djokovic, Cristina Borges, Eric J. Ley, Antonio Duarte, and Parkash S. Gill Blood 2007 109: 4753-4760. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-12-063933 [Abstract] [Full Text] [PDF] [Supplemental Figure]   In vivo vasculogenic potential of human blood-derived endothelial progenitor cells Juan M. Melero-Martin, Zia A. Khan, Arnaud Picard, Xiao Wu, Sailaja Paruchuri, and Joyce Bischoff Blood 2007 109: 4761-4768. Prepublished online February 27, 2007; DOI 10.1182/blood-2006-12-062471 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Regulation of protein C inhibitor (PCI) activity by specific oxidized and negatively charged phospholipids Julia M. Malleier, Olga Oskolkova, Valery Bochkov, Ingrid Jerabek, Barbora Sokolikova, Thomas Perkmann, Johannes Breuss, Bernd R. Binder, and Margarethe Geiger Blood 2007 109: 4769-4776. Prepublished online March 1, 2007; DOI 10.1182/blood-2006-09-046953 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Blood and lymphatic endothelial cell-specific differentiation programs are stringently controlled by the tissue environment Stefan Amatschek, Ernst Kriehuber, Wolfgang Bauer, Barbel Reininger, Paul Meraner, Alois Wolpl, Norbert Schweifer, Christian Haslinger, Georg Stingl, and Dieter Maurer Blood 2007 109: 4777-4785. Prepublished online February 8, 2007; DOI 10.1182/blood-2006-10-053280 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]   Moderation of the platelet releasate response by aspirin Judith A. Coppinger, Roisin O'Connor, Kieran Wynne, Michelle Flanagan, Matthew Sullivan, Patricia B. Maguire, Desmond J. Fitzgerald, and Gerard Cagney Blood 2007 109: 4786-4792. Prepublished online February 15, 2007; DOI 10.1182/blood-2006-07-038539 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]   Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both autophagy and apoptotic death in endothelial cells Tri Minh Bui Nguyen, Indira V. Subramanian, Ameeta Kelekar, and Sundaram Ramakrishnan Blood 2007 109: 4793-4802. Prepublished online February 1, 2007; DOI 10.1182/blood-2006-11-059352 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Brief report  Platelet-bound lipopolysaccharide enhances Fc receptor–mediated phagocytosis of IgG-opsonized platelets John W. Semple, Rukhsana Aslam, Michael Kim, Edwin R. Speck, and John Freedman Blood 2007 109: 4803-4805. Prepublished online February 13, 2007; DOI 10.1182/blood-2006-12-062695 [Abstract] [Full Text] [PDF]   Brief report  The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro Stephen A. Newland, Iain C. Macaulay, Andres R. Floto, Edwin C. de Vet, Willem H. Ouwehand, Nicholas A. Watkins, Paul A. Lyons, and Duncan R. Campbell Blood 2007 109: 4806-4809. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-09-047449 [Abstract] [Full Text] [PDF] [Supplemental Methods, Table, and Figures]   IMMUNOBIOLOGY: Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation Ruth R. French, Vadim Y. Taraban, Graham R. Crowther, Tania F. Rowley, Juliet C. Gray, Peter W. Johnson, Alison L. Tutt, Aymen Al-Shamkhani, and Martin J. Glennie Blood 2007 109: 4810-4815. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-11-057216 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Reduced natural killer (NK) function associated with high-risk myelodysplastic syndrome (MDS) and reduced expression of activating NK receptors Pearlie K. Epling-Burnette, Fanqi Bai, Jeffrey S. Painter, Dana E. Rollison, Helmut R. Salih, Matthias Krusch, JianXiang Zou, Edna Ku, Bin Zhong, David Boulware, Lynn Moscinski, Sheng Wei, Julie Y. Djeu, and Alan F. List Blood 2007 109: 4816-4824. Prepublished online March 6, 2007; DOI 10.1182/blood-2006-07-035519 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Interferon-producing killer dendritic cells (IKDCs) arise via a unique differentiation pathway from primitive c-kitHiCD62L+ lymphoid progenitors Robert S. Welner, Rosana Pelayo, Karla P. Garrett, Xinrong Chen, S. Scott Perry, Xiao-Hong Sun, Barbara L. Kee, and Paul W. Kincade Blood 2007 109: 4825-4931. Prepublished online February 22, 2007; DOI 10.1182/blood-2006-08-043810 [Abstract] [Full Text] [PDF] [Supplemental Figures]   HIV-1–specific CTLs effectively suppress replication of HIV-1 in HIV-1–infected macrophages Mamoru Fujiwara and Masafumi Takiguchi Blood 2007 109: 4832-4838. Prepublished online February 15, 2007; DOI 10.1182/blood-2006-07-037481 [Abstract] [Full Text] [PDF]   Bortezomib enhances dendritic cell (DC)–mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications Radek Spisek, Anna Charalambous, Amitabha Mazumder, David H. Vesole, Sundar Jagannath, and Madhav V. Dhodapkar Blood 2007 109: 4839-4845. Prepublished online February 13, 2007; DOI 10.1182/blood-2006-10-054221 [Abstract] [Full Text] [PDF]   Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections Nobuhiro Nakano, Chiharu Nishiyama, Shunsuke Kanada, Yusuke Niwa, Naomi Shimokawa, Hiroko Ushio, Makoto Nishiyama, Ko Okumura, and Hideoki Ogawa Blood 2007 109: 4846-4855. Prepublished online February 8, 2007; DOI 10.1182/blood-2006-09-045641 [Abstract] [Full Text] [PDF]   T cell–dependent survival of CD20+ and CD20– plasma cells in human secondary lymphoid tissue David R. Withers, Claudia Fiorini, Randy T. Fischer, Rachel Ettinger, Peter E. Lipsky, and Amrie C. Grammer Blood 2007 109: 4856-4864. Prepublished online February 13, 2007; DOI 10.1182/blood-2006-08-043414 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Adoptive transfer of tumor-primed, in vitro–activated, CD4+ T effector cells (TEs) combined with CD8+ TEs provides intratumoral TE proliferation and synergistic antitumor response Li-Xin Wang, Suyu Shu, Mary L. Disis, and Gregory E. Plautz Blood 2007 109: 4865-4876. Prepublished online February 6, 2007; DOI 10.1182/blood-2006-09-045245 [Abstract] [Full Text] [PDF]   Functional characterization of natural killer cells in type I leukocyte adhesion deficiency Roberta Castriconi, Alessandra Dondero, Claudia Cantoni, Mariella Della Chiesa, Carola Prato, Marina Nanni, Maurilia Fiorini, Lucia Notarangelo, Silvia Parolini, Lorenzo Moretta, Luigi Notarangelo, Alessandro Moretta, and Cristina Bottino Blood 2007 109: 4873-4881. Prepublished online February 1, 2007; DOI 10.1182/blood-2006-08-038760 [Abstract] [Full Text] [PDF]   CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype Yuwen Zhu, Gefeng Zhu, Liqun Luo, Andrew S. Flies, and Lieping Chen Blood 2007 109: 4882-4889. Prepublished online January 23, 2007; DOI 10.1182/blood-2006-10-043463 [Abstract] [Full Text] [PDF]   NEOPLASIA: Monoclonal TCR-Vβ13.1+/CD4+/NKa+/CD8–/+dim T-LGL lymphocytosis: evidence for an antigen-driven chronic T-cell stimulation origin Pilar Garrido, Francisco Ruiz-Cabello, Paloma Bárcena, Yorick Sandberg, Julia Cantón, Margarida Lima, Ana Balanzategui, Marcos González, Miguel Angel López-Nevot, Anton W. Langerak, Andrés C. García-Montero, Julia Almeida, and Alberto Orfao Blood 2007 109: 4890-4898. Prepublished online February 15, 2007; DOI 10.1182/blood-2006-05-022277 [Abstract] [Full Text] [PDF]   Development of a murine model for blastoid variant mantle-cell lymphoma Richard J. Ford, Long Shen, Yen Chiu Lin-Lee, Lan V. Pham, Asha Multani, Hai-Jun Zhou, Archito T. Tamayo, ChongJie Zhang, Lesleyann Hawthorn, John K. Cowell, and Julian L. Ambrus, Jr Blood 2007 109: 4899-4906. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-08-038497 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Endogenous bcl-2 is not required for the development of Eµ-myc–induced B-cell lymphoma Priscilla N. Kelly, Hamsa Puthalakath, Jerry M. Adams, and Andreas Strasser Blood 2007 109: 4907-4913. Prepublished online February 22, 2007; DOI 10.1182/blood-2006-10-051847 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma Karène Mahtouk, Dirk Hose, Pierre Raynaud, Michael Hundemer, Michel Jourdan, Eric Jourdan, Veronique Pantesco, Marion Baudard, John De Vos, Marion Larroque, Thomas Moehler, Jean-Francois Rossi, Thierry Rème, Hartmut Goldschmidt, and Bernard Klein Blood 2007 109: 4914-4923. Prepublished online March 5, 2007; DOI 10.1182/blood-2006-08-043232 [Abstract] [Full Text] [PDF]   The myeloproliferative disorder–associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3 Michelle B. Hookham, Joanne Elliott, Yvonne Suessmuth, Judith Staerk, Alister C. Ward, William Vainchenker, Melanie J. Percy, Mary Frances McMullin, Stefan N. Constantinescu, and James A. Johnston Blood 2007 109: 4924-4929. Prepublished online February 22, 2007; DOI 10.1182/blood-2006-08-039735 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Prognostic impact of immunohistochemically defined germinal center phenotype in diffuse large B-cell lymphoma patients treated with immunochemotherapy Heidi Nyman, Magdalena Adde, Marja-Liisa Karjalainen-Lindsberg, Minna Taskinen, Mattias Berglund, Rose-Marie Amini, Carl Blomqvist, Gunilla Enblad, and Sirpa Leppä Blood 2007 109: 4930-4935. Prepublished online February 13, 2007; DOI 10.1182/blood-2006-09-047068 [Abstract] [Full Text] [PDF] [Supplemental Tables]   p53 status dictates responses of B lymphomas to monotherapy with proteasome inhibitors Duonan Yu, Martin Carroll, and Andrei Thomas-Tikhonenko Blood 2007 109: 4936-4943. Prepublished online February 6, 2007; DOI 10.1182/blood-2006-10-050294 [Abstract] [Full Text] [PDF]   Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia Valerio Fulci, Sabina Chiaretti, Marina Goldoni, Gianluca Azzalin, Nicoletta Carucci, Simona Tavolaro, Leandro Castellano, Armando Magrelli, Franca Citarella, Monica Messina, Roberta Maggio, Nadia Peragine, Simona Santangelo, Francesca Romana Mauro, Pablo Landgraf, Thomas Tuschl, David B. Weir, Minchen Chien, James J. Russo, Jingyue Ju, Robert Sheridan, Chris Sander, Mihaela Zavolan, Anna Guarini, Robin Foà, and Giuseppe Macino Blood 2007 109: 4944-4951. Prepublished online February 27, 2007; DOI 10.1182/blood-2006-12-062398 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]   The gene expression profile of nodal peripheral T-cell lymphoma demonstrates a molecular link between angioimmunoblastic T-cell lymphoma (AITL) and follicular helper T (TFH) cells Laurence de Leval, David S. Rickman, Caroline Thielen, Aurélien de Reynies, Yen-Lin Huang, Georges Delsol, Laurence Lamant, Karen Leroy, Josette Brière, Thierry Molina, Françoise Berger, Christian Gisselbrecht, Luc Xerri, and Philippe Gaulard Blood 2007 109: 4952-4963. Prepublished online February 6, 2007; DOI 10.1182/blood-2006-10-055145 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figure]   Protein kinase C inhibitor enzastaurin induces in vitro and in vivo antitumor activity in Waldenström macroglobulinemia Anne-Sophie Moreau, Xiaoying Jia, Hai T. Ngo, Xavier Leleu, Garrett O'Sullivan, Yazan Alsayed, Alexey Leontovich, Klaus Podar, Jeffrey Kutok, John Daley, Suzan Lazo-Kallanian, Evdoxia Hatjiharissi, Marc S. Raab, Lian Xu, Steven P. Treon, Teru Hideshima, Kenneth C. Anderson, and Irene M. Ghobrial Blood 2007 109: 4964-4972. Prepublished online February 6, 2007; DOI 10.1182/blood-2006-10-054577 [Abstract] [Full Text] [PDF]   CLLU1 expression analysis adds prognostic information to risk prediction in chronic lymphocytic leukemia Pär Josefsson, Christian H. Geisler, Henrik Leffers, Jørgen H. Petersen, Mette K. Andersen, Jesper Jurlander, and Anne Mette Buhl Blood 2007 109: 4973-4979. Prepublished online February 6, 2007; DOI 10.1182/blood-2006-11-054916 [Abstract] [Full Text] [PDF]   Comparative biodistributions of pretargeted radioimmunoconjugates targeting CD20, CD22, and DR molecules on human B-cell lymphomas Anastasia Pantelias, John M. Pagel, Nathan Hedin, Laura Saganic, Shani Wilbur, Donald K. Hamlin, D. Scott Wilbur, Yukang Lin, Diane Stone, Don Axworthy, Ajay K. Gopal, and Oliver W. Press Blood 2007 109: 4980-4987. Prepublished online February 15, 2007; DOI 10.1182/blood-2006-11-056895 [Abstract] [Full Text] [PDF]   The mitochondrial effects of novel apoptogenic molecules generated by psoralen photolysis as a crucial mechanism in PUVA therapy Sergio Caffieri, Fabio Di Lisa, Federico Bolesani, Monica Facco, Gianpietro Semenzato, Francesco Dall'Acqua, and Marcella Canton Blood 2007 109: 4988-4994. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-08-037192 [Abstract] [Full Text] [PDF]   CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms Fenghuang Zhan, Simona Colla, Xiaosong Wu, Bangzheng Chen, James P. Stewart, W. Michael Kuehl, Bart Barlogie, and John D. Shaughnessy, Jr Blood 2007 109: 4995-5001. Prepublished online February 15, 2007; DOI 10.1182/blood-2006-07-038703 [Abstract] [Full Text] [PDF]   CD28-mediated regulation of multiple myeloma cell proliferation and survival Nizar J. Bahlis, Anne M. King, Despina Kolonias, Louise M. Carlson, Hong Yu Liu, Mohamad A. Hussein, Howard R. Terebelo, Gerald E. Byrne, Jr, Bruce L. Levine, Lawrence H. Boise, and Kelvin P. Lee Blood 2007 109: 5002-5010. Prepublished online February 20, 2007; DOI 10.1182/blood-2006-03-012542 [Abstract] [Full Text] [PDF]   Identification of BCR-ABL point mutations conferring resistance to the Abl kinase inhibitor AMN107 (nilotinib) by a random mutagenesis study Arghya Ray, Sandra W. Cowan-Jacob, Paul W. Manley, Jürgen Mestan, and James D. Griffin Blood 2007 109: 5011-5015. Prepublished online February 15, 2007; DOI 10.1182/blood-2006-01-015347 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Hsp90 regulates the Fanconi anemia DNA damage response pathway Tsukasa Oda, Toshiya Hayano, Hidenobu Miyaso, Nobuhiro Takahashi, and Takayuki Yamashita Blood 2007 109: 5016-5026. Prepublished online February 27, 2007; DOI 10.1182/blood-2006-08-038638 [Abstract] [Full Text] [PDF]   RED CELLS: Ineffective erythropoiesis in β-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin Sara Gardenghi, Maria F. Marongiu, Pedro Ramos, Ella Guy, Laura Breda, Amy Chadburn, YiFang Liu, Ninette Amariglio, Gideon Rechavi, Eliezer A. Rachmilewitz, William Breuer, Z. Ioav Cabantchik, Diedra M. Wrighting, Nancy C. Andrews, Maria de Sousa, Patricia J. Giardina, Robert W. Grady, and Stefano Rivella Blood 2007 109: 5027-5035. Prepublished online February 13, 2007; DOI 10.1182/blood-2006-09-048868 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Highly homologous T-cell receptor beta sequences support a common target for autoreactive T cells in most patients with paroxysmal nocturnal hemoglobinuria Lucia Gargiulo, Sonia Lastraioli, Giannamaria Cerruti, Martina Serra, Fabrizio Loiacono, Simona Zupo, Lucio Luzzatto, and Rosario Notaro Blood 2007 109: 5036-5042. Prepublished online February 6, 2007; DOI 10.1182/blood-2006-10-052381 [Abstract] [Full Text] [PDF]   STEM CELLS IN HEMATOLOGY: Steel factor responsiveness regulates the high self-renewal phenotype of fetal hematopoietic stem cells Michelle B. Bowie, David G. Kent, Michael R. Copley, and Connie J. Eaves Blood 2007 109: 5043-5048. Prepublished online February 27, 2007; DOI 10.1182/blood-2006-08-037770 [Abstract] [Full Text] [PDF]   TRANSPLANTATION: Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHD Kelli P. A. MacDonald, Rachel D. Kuns, Vanessa Rowe, Edward S. Morris, Tatjana Banovic, Helen Bofinger, Brendan O'Sullivan, Kate A. Markey, Alistair L. Don, Ranjeny Thomas, and Geoffrey R. Hill Blood 2007 109: 5049-5057. Prepublished online February 27, 2007; DOI 10.1182/blood-2007-01-067249 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Brief report  Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT Jeffery S. Miller, Sarah Cooley, Peter Parham, Sherif S. Farag, Michael R. Verneris, Karina L. McQueen, Lisbeth A. Guethlein, Elizabeth A. Trachtenberg, Michael Haagenson, Mary M. Horowitz, John P. Klein, and Daniel J. Weisdorf Blood 2007 109: 5058-5061. Prepublished online February 22, 2007; DOI 10.1182/blood-2007-01-065383 [Abstract] [Full Text] [PDF]   CORRESPONDENCE: Isolated high-molecular-weight kininogen deficiency: a novel frameshift mutation in exon 10 Toshio Shigekiyo, Junko Miyagi, Atsuhisa Shirakami, Hironobu Shibata, Kazuo Tsukai, and Ken-ichi Aihara Blood 2007 109: 5062-5063. [Full Text] [PDF]   Donor lymphocyte infusions for the treatment of minimal residual disease in acute leukemia Alida Dominietto, Sarah Pozzi, Maurizio Miglino, Flavio Albarracin, Giovanna Piaggio, Francesca Bertolotti, Raffaella Grasso, Simona Zupo, Anna Maria Raiola, Marco Gobbi, Francesco Frassoni, and Andrea Bacigalupo Blood 2007 109: 5063-5064. [Full Text] [PDF]   Killer cell Ig-like receptors CD158a and CD158b display a coactivatory function, involving the c-Jun NH2-terminal protein kinase signaling pathway, when expressed on malignant CD4+ T cells from a patient with Sézary syndrome Anne Marie-Cardine, Delphine Huet, Nicolas Ortonne, Natacha Remtoula, Sabine Le Gouvello, Martine Bagot, and Armand Bensussan Blood 2007 109: 5064-5065. [Full Text] [PDF]   ERRATUM: Erratum for Vlasáková et al., Histone deacetylase inhibitors suppress IFN-induced up-regulation of promyelocytic leukemia protein Blood 2007 109: 4606. [Full Text] [PDF]   Erratum for Fraser et al entitled Maturation and enucleation of primitive erythroblasts during mouse embryogenesis is accompanied by changes in cell-surface antigen expression Blood 2007 109: 4616. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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