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Receive this page by email each issue: [Sign up for eTOCs] Other Issues: September 15 2007; 110 (6)   [Index by Author]  [Cover Caption]  [Complete Inside Blood PDF]         INSIDE BLOOD        PERSPECTIVE        REVIEW IN TRANSLATIONAL HEMATOLOGY        CHEMOKINES, CYTOKINES, AND INTERLEUKINS        CLINICAL TRIALS AND OBSERVATIONS        GENE THERAPY        HEMATOPOIESIS        HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY        IMMUNOBIOLOGY        NEOPLASIA        RED CELLS        STEM CELLS IN HEMATOLOGY        TRANSFUSION MEDICINE        TRANSPLANTATION        CORRESPONDENCE Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: Iron can boost hepcidin both ways Prem Ponka and Bill Andriopoulos Blood 2007 110: 1703-1704. [Full Text] [PDF]   RIS defines risk Utpal P. Davé Blood 2007 110: 1704. [Full Text] [PDF]   FHL4: NK cells pack less punch Kim E. Nichols Blood 2007 110: 1705-1706. [Full Text] [PDF]   Lock 'n' roll with VAP-1 Suchitra Sumitran-Holgersson Blood 2007 110: 1706-1707. [Full Text] [PDF]   Division of labor for oncogene BCL6 Alexander Dent Blood 2007 110: 1707-1708. [Full Text] [PDF]   Watch out, MF! Dan L. Longo Blood 2007 110: 1708-1709. [Full Text] [PDF]   A pill for some anemias? Derek A. Persons Blood 2007 110: 1709. [Full Text] [PDF]   CD40 promotes lymphoma from nuclear hideaway Davide Rossi and Gianluca Gaidano Blood 2007 110: 1710-1711. [Full Text] [PDF]   Attractive shedding Frank R. DeLeo Blood 2007 110: 1711-1712. [Full Text] [PDF]   PERSPECTIVE: Revisions to the staging and classification of mycosis fungoides and Sézary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC) Elise Olsen, Eric Vonderheid, Nicola Pimpinelli, Rein Willemze, Youn Kim, Robert Knobler, Herschel Zackheim, Madeleine Duvic, Teresa Estrach, Stanford Lamberg, Gary Wood, Reinhard Dummer, Annamari Ranki, Gunter Burg, Peter Heald, Mark Pittelkow, Maria-Grazia Bernengo, Wolfram Sterry, Liliane Laroche, Franz Trautinger, and Sean Whittaker, for the ISCL/EORTC Blood 2007 110: 1713-1722. Prepublished online May 31, 2007; DOI 10.1182/blood-2007-03-055749 [Abstract] [Full Text] [PDF] [Supplemental Appendices]   REVIEW IN TRANSLATIONAL HEMATOLOGY: Trousseau's syndrome: multiple definitions and multiple mechanisms Ajit Varki Blood 2007 110: 1723-1729. Prepublished online May 11, 2007; DOI 10.1182/blood-2006-10-053736 [Abstract] [Full Text] [PDF]   CHEMOKINES, CYTOKINES, AND INTERLEUKINS: p52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells Laura Patrussi, Cristina Ulivieri, Orso Maria Lucherini, Silvia Rossi Paccani, Alessandra Gamberucci, Luisa Lanfrancone, Pier Giuseppe Pelicci, and Cosima T. Baldari Blood 2007 110: 1730-1738. Prepublished online May 30, 2007; DOI 10.1182/blood-2007-01-068411 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Lipid rafts are required for Kit survival and proliferation signals Thomas Jahn, Erica Leifheit, Stacie Gooch, Simran Sindhu, and Kenneth Weinberg Blood 2007 110: 1739-1747. Prepublished online June 6, 2007; DOI 10.1182/blood-2006-05-020925 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils Athena Chalaris, Björn Rabe, Krzysztof Paliga, Hans Lange, Tamas Laskay, Ceri A. Fielding, Simon A. Jones, Stefan Rose-John, and Jürgen Scheller Blood 2007 110: 1748-1755. Prepublished online June 13, 2007; DOI 10.1182/blood-2007-01-067918 [Abstract] [Full Text] [PDF] [Supplemental Figures]   CLINICAL TRIALS AND OBSERVATIONS: Treatment of severe aplastic anemia with antithymocyte globulin and cyclosporin A with or without G-CSF in adults: a multicenter randomized study in Japan Masanao Teramura, Akiro Kimura, Satsuki Iwase, Yuji Yonemura, Shinji Nakao, Akio Urabe, Mitsuhiro Omine, and Hideaki Mizoguchi Blood 2007 110: 1756-1761. Prepublished online May 25, 2007; DOI 10.1182/blood-2006-11-050526 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   A phase 1 clinical-laboratory study of clofarabine followed by cyclophosphamide for adults with refractory acute leukemias Judith E. Karp, Rebecca M. Ricklis, Kumudha Balakrishnan, Janet Briel, Jacqueline Greer, Steven D. Gore, B. Douglas Smith, Michael A. McDevitt, Hetty Carraway, Mark J. Levis, and Varsha Gandhi Blood 2007 110: 1762-1769. Prepublished online June 11, 2007; DOI 10.1182/blood-2007-03-081364 [Abstract] [Full Text] [PDF]   GENE THERAPY: Hot spots of retroviral integration in human CD34+ hematopoietic cells Claudia Cattoglio, Giulia Facchini, Daniela Sartori, Antonella Antonelli, Annarita Miccio, Barbara Cassani, Manfred Schmidt, Christof von Kalle, Steve Howe, Adrian J. Thrasher, Alessandro Aiuti, Giuliana Ferrari, Alessandra Recchia, and Fulvio Mavilio Blood 2007 110: 1770-1778. Prepublished online May 16, 2007; DOI 10.1182/blood-2007-01-068759 [Abstract] [Full Text] [PDF] [Supplemental Tables]   Stable differentiation and clonality of murine long-term hematopoiesis after extended reduced-intensity selection for MGMT P140K transgene expression Claudia R. Ball, Ingo H. Pilz, Manfred Schmidt, Sylvia Fessler, David A. Williams, Christof von Kalle, and Hanno Glimm Blood 2007 110: 1779-1787. Prepublished online May 11, 2007; DOI 10.1182/blood-2006-11-053710 [Abstract] [Full Text] [PDF] [Supplemental Table]   The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4+CD25+ regulatory T cells Andrea Annoni, Manuela Battaglia, Antonia Follenzi, Angelo Lombardo, Lucia Sergi-Sergi, Luigi Naldini, and Maria-Grazia Roncarolo Blood 2007 110: 1788-1796. Prepublished online May 10, 2007; DOI 10.1182/blood-2006-11-059873 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences Agnete Brunsvik Fredriksen and Bjarne Bogen Blood 2007 110: 1797-1805. Prepublished online May 31, 2007; DOI 10.1182/blood-2006-06-032938 [Abstract] [Full Text] [PDF] [Supplemental Methods and Table]   HEMATOPOIESIS: Hematopoietic stem-cell behavior in nonhuman primates Bryan E. Shepherd, Hans-Peter Kiem, Peter M. Lansdorp, Cynthia E. Dunbar, Geraldine Aubert, Andre LaRochelle, Ruth Seggewiss, Peter Guttorp, and Janis L. Abkowitz Blood 2007 110: 1806-1813. Prepublished online May 25, 2007; DOI 10.1182/blood-2007-02-075382 [Abstract] [Full Text] [PDF]   The Hedgehog receptor Patched controls lymphoid lineage commitment Anja Uhmann, Kai Dittmann, Frauke Nitzki, Ralf Dressel, Milena Koleva, Anke Frommhold, Arne Zibat, Claudia Binder, Ibrahim Adham, Mirko Nitsche, Tanja Heller, Victor Armstrong, Walter Schulz-Schaeffer, Jürgen Wienands, and Heidi Hahn Blood 2007 110: 1814-1823. Prepublished online May 29, 2007; DOI 10.1182/blood-2007-02-075648 [Abstract] [Full Text] [PDF]   The role of jak2a in zebrafish hematopoiesis Alvin C. H. Ma, Alister C. Ward, Raymond Liang, and Anskar Y. H. Leung Blood 2007 110: 1824-1830. Prepublished online June 1, 2007; DOI 10.1182/blood-2007-03-078287 [Abstract] [Full Text] [PDF] [Supplemental Table]   Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia Robert A. J. Signer, Encarnacion Montecino-Rodriguez, Owen N. Witte, Jami McLaughlin, and Kenneth Dorshkind Blood 2007 110: 1831-1839. Prepublished online June 6, 2007; DOI 10.1182/blood-2007-01-069401 [Abstract] [Full Text] [PDF]   Direct interaction between Kit and the interleukin-7 receptor Thomas Jahn, Simran Sindhu, Stacie Gooch, Petra Seipel, Philip Lavori, Erica Leifheit, and Kenneth Weinberg Blood 2007 110: 1840-1847. Prepublished online June 6, 2007; DOI 10.1182/blood-2005-12-028019 [Abstract] [Full Text] [PDF] [Supplemental Figures]   HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY: JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration Abigail Woodfin, Christoph Andreas Reichel, Andrej Khandoga, Monica Corada, Mathieu-Benoit Voisin, Christoph Scheiermann, Dorian O. Haskard, Elisabetta Dejana, Fritz Krombach, and Sussan Nourshargh Blood 2007 110: 1848-1856. Prepublished online May 15, 2007; DOI 10.1182/blood-2006-09-047431 [Abstract] [Full Text] [PDF]   High T-cell response to human cytomegalovirus induces chemokine-mediated endothelial cell damage Cynthia A. Bolovan-Fritts, Rodney N. Trout, and Stephen A. Spector Blood 2007 110: 1857-1863. Prepublished online May 22, 2007; DOI 10.1182/blood-2007-03-078881 [Abstract] [Full Text] [PDF] [Supplemental Methods]   The oxidase activity of vascular adhesion protein-1 (VAP-1) induces endothelial E- and P-selectins and leukocyte binding Sirpa Jalkanen, Marika Karikoski, Nathalie Mercier, Kaisa Koskinen, Tiina Henttinen, Kati Elima, Katriina Salmivirta, and Marko Salmi Blood 2007 110: 1864-1870. Prepublished online June 4, 2007; DOI 10.1182/blood-2007-01-069674 [Abstract] [Full Text] [PDF]   The low-molecular-weight phosphotyrosine phosphatase is a negative regulator of FcRIIA-mediated cell activation Francesca Mancini, Stefania Rigacci, Andrea Berti, Cesare Balduini, and Mauro Torti Blood 2007 110: 1871-1878. Prepublished online May 30, 2007; DOI 10.1182/blood-2007-03-081414 [Abstract] [Full Text] [PDF]   Conversion of platelets from a proaggregatory to a proinflammatory adhesive phenotype: role of PAF in spatially regulating neutrophil adhesion and spreading Suhasini Kulkarni, Kevin J. Woollard, Stephen Thomas, David Oxley, and Shaun P. Jackson Blood 2007 110: 1879-1886. Prepublished online June 4, 2007; DOI 10.1182/blood-2006-08-040980 [Abstract] [Full Text] [PDF] [Supplemental Figures and Videos]   The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow Ping Zhang, Weilan Pan, Ann H. Rux, Bruce S. Sachais, and X. Long Zheng Blood 2007 110: 1887-1894. Prepublished online May 31, 2007; DOI 10.1182/blood-2007-04-083329 [Abstract] [Full Text] [PDF]   A critical role for TNF in the selective attachment of mononuclear leukocytes to angiotensin-II-stimulated arterioles Teresa Mateo, Yafa Naim Abu Nabah, Mercedes Losada, Rossana Estellés, Chantal Company, Begoña Bedrina, Jose Miguel Cerdá-Nicolás, Stephen Poole, Peter J. Jose, Julio Cortijo, Esteban J. Morcillo, and Maria-Jesus Sanz Blood 2007 110: 1895-1902. Prepublished online June 26, 2007; DOI 10.1182/blood-2007-01-070607 [Abstract] [Full Text] [PDF]   Brief report  Endogenous platelet factor 4 stimulates activated protein C generation in vivo and improves survival after thrombin or lipopolysaccharide challenge M. Anna Kowalska, Shawn A. Mahmud, Michele P. Lambert, Mortimer Poncz, and Arne Slungaard Blood 2007 110: 1903-1905. Prepublished online May 31, 2007; DOI 10.1182/blood-2007-03-081901 [Abstract] [Full Text] [PDF]   IMMUNOBIOLOGY: Defective cytotoxic lymphocyte degranulation in syntaxin-11–deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients Yenan T. Bryceson, Eva Rudd, Chengyun Zheng, Josefine Edner, Daoxin Ma, Stephanie M. Wood, Anne Grete Bechensteen, Jaap J. Boelens, Tiraje Celkan, Roula A. Farah, Kjell Hultenby, Jacek Winiarski, Paul A. Roche, Magnus Nordenskjöld, Jan-Inge Henter, Eric O. Long, and Hans-Gustaf Ljunggren Blood 2007 110: 1906-1915. Prepublished online May 24, 2007; DOI 10.1182/blood-2007-02-074468 [Abstract] [Full Text] [PDF]   Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: implications for their use as vaccines Nia Tatsis, Julie C. Fitzgerald, Arturo Reyes-Sandoval, Kimberly C. Harris-McCoy, Scott E. Hensley, Dongming Zhou, Shih-Wen Lin, Ang Bian, Zhi Quan Xiang, Amaya Iparraguirre, Cesar Lopez-Camacho, E. John Wherry, and Hildegund C. J. Ertl Blood 2007 110: 1916-1923. Prepublished online May 17, 2007; DOI 10.1182/blood-2007-02-062117 [Abstract] [Full Text] [PDF]   Graft-versus-leukemia effects associated with detectable Wilms tumor-1–specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia Katayoun Rezvani, Agnes S. M. Yong, Bipin N. Savani, Stephan Mielke, Keyvan Keyvanfar, Emma Gostick, David A. Price, Daniel C. Douek, and A. John Barrett Blood 2007 110: 1924-1932. Prepublished online May 15, 2007; DOI 10.1182/blood-2007-03-076844 [Abstract] [Full Text] [PDF]   Gata1 regulates dendritic-cell development and survival Laura Gutiérrez, Tatjana Nikolic, Thamar B. van Dijk, Hamida Hammad, Nanda Vos, Monique Willart, Frank Grosveld, Sjaak Philipsen, and Bart N. Lambrecht Blood 2007 110: 1933-1941. Prepublished online May 15, 2007; DOI 10.1182/blood-2006-09-048322 [Abstract] [Full Text] [PDF] [Supplemental Methods]   Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells Christopher J. Ong, Andrew Ming-Lum, Matt Nodwell, Ali Ghanipour, Lu Yang, David E. Williams, Joseph Kim, Loutfig Demirjian, Pooran Qasimi, Jens Ruschmann, Li-Ping Cao, Kewei Ma, Stephen W. Chung, Vincent Duronio, Raymond J. Andersen, Gerald Krystal, and Alice L.-F. Mui Blood 2007 110: 1942-1949. Prepublished online May 14, 2007; DOI 10.1182/blood-2007-03-079699 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis Andrea White, Damian Carragher, Sonia Parnell, Aichi Msaki, Neil Perkins, Peter Lane, Eric Jenkinson, Graham Anderson, and Jorge H. Caamaño Blood 2007 110: 1950-1959. Prepublished online May 25, 2007; DOI 10.1182/blood-2007-01-070003 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figure]   Bone marrow CD8 cells down-modulate membrane IL-7R expression and exhibit increased STAT-5 and p38 MAPK phosphorylation in the organ environment. Giuliana Cassese, Elisabetta Parretta, Laura Pisapia, Angela Santoni, John Guardiola, and Francesca Di Rosa Blood 2007 110: 1960-1969. Prepublished online May 17, 2007; DOI 10.1182/blood-2006-09-045807 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA Stanimir Ivanov, Ana-Maria Dragoi, Xin Wang, Corrado Dallacosta, Jennifer Louten, Giovanna Musco, Giovanni Sitia, George S. Yap, Yinsheng Wan, Christine A. Biron, Marco E. Bianchi, Haichao Wang, and Wen-Ming Chu Blood 2007 110: 1970-1981. Prepublished online June 4, 2007; DOI 10.1182/blood-2006-09-044776 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Farnesyltransferase inhibitors inhibit T-cell cytokine production at the posttranscriptional level Reinhard E. Marks, Allen W. Ho, Christian Robbel, Todd Kuna, Seth Berk, and Thomas F. Gajewski Blood 2007 110: 1982-1988. Prepublished online June 1, 2007; DOI 10.1182/blood-2006-06-031088 [Abstract] [Full Text] [PDF]   Platelet particle formation by anti–GPIIIa49-66 Ab, Ca2+ ionophore A23187, and phorbol myristate acetate is induced by reactive oxygen species and inhibited by dexamethasone blockade of platelet phospholipase A2, 12-lipoxygenase, and NADPH oxidase Michael A. Nardi, Yelena Gor, Steven J. Feinmark, Fang Xu, and Simon Karpatkin Blood 2007 110: 1989-1996. Prepublished online June 1, 2007; DOI 10.1182/blood-2006-10-054064 [Abstract] [Full Text] [PDF]   Cytotoxic T lymphocytes carrying a pattern recognition protein Tag7 can detect evasive, HLA-negative but Hsp70-exposing tumor cells, thereby ensuring FasL/Fas-mediated contact killing Lidia P. Sashchenko, Elena A. Dukhanina, Yury V. Shatalov, Denis V. Yashin, Tamara I. Lukyanova, Olga D. Kabanova, Elena A. Romanova, Sergei V. Khaidukov, Alexander V. Galkin, Nikolai V. Gnuchev, and Georgii P. Georgiev Blood 2007 110: 1997-2004. Prepublished online June 5, 2007; DOI 10.1182/blood-2006-12-064444 [Abstract] [Full Text] [PDF] [Supplemental Figures]   CD34 facilitates the development of allergic asthma Marie-Renée Blanchet, Steven Maltby, D. James Haddon, Helen Merkens, Lori Zbytnuik, and Kelly M. McNagny Blood 2007 110: 2005-2012. Prepublished online June 8, 2007; DOI 10.1182/blood-2006-12-062448 [Abstract] [Full Text] [PDF]   An NKT-mediated autologous vaccine generates CD4 T-cell–dependent potent antilymphoma immunity Yeonseok Chung, Hong Qin, Chang-Yuil Kang, Sanghee Kim, Larry W. Kwak, and Chen Dong Blood 2007 110: 2013-2019. Prepublished online June 20, 2007; DOI 10.1182/blood-2006-12-061309 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Brief report  2B4 inhibits NK-cell fratricide Ruth T. Taniguchi, Dustin Guzior, and Vinay Kumar Blood 2007 110: 2020-2023. Prepublished online May 30, 2007; DOI 10.1182/blood-2007-02-076927 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Brief report  Rapid generation of a functional NK-cell compartment Martin Prlic, Daisuke Kamimura, and Michael J. Bevan Blood 2007 110: 2024-2026. Prepublished online June 6, 2007; DOI 10.1182/blood-2007-04-086108 [Abstract] [Full Text] [PDF] [Supplemental Figures]   NEOPLASIA: Novel RUNX1 isoforms determine the fate of acute myeloid leukemia cells by controlling CD56 expression Stefan Gattenloehner, Sergei Chuvpilo, Claudia Langebrake, Dirk Reinhardt, Hans-Konrad Müller-Hermelink, Edgar Serfling, Angela Vincent, and Alexander Marx Blood 2007 110: 2027-2033. Prepublished online April 12, 2007; DOI 10.1182/blood-2007-02-074203 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures][Additional Supplemental Figures]   AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo Jing Yang, Takayuki Ikezoe, Chie Nishioka, Taizo Tasaka, Ayuko Taniguchi, Yoshio Kuwayama, Naoki Komatsu, Kentaro Bandobashi, Kazuto Togitani, H. Phillip Koeffler, Hirokuni Taguchi, and Akihito Yokoyama Blood 2007 110: 2034-2040. Prepublished online May 10, 2007; DOI 10.1182/blood-2007-02-073700 [Abstract] [Full Text] [PDF]   The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy Yang Yang, Veronica MacLeod, Yuemeng Dai, Yekaterina Khotskaya-Sample, Zachary Shriver, Ganesh Venkataraman, Ram Sasisekharan, Annamaria Naggi, Giangiacomo Torri, Benito Casu, Israel Vlodavsky, Larry J. Suva, Joshua Epstein, Shmuel Yaccoby, John D. Shaughnessy, Jr, Bart Barlogie, and Ralph D. Sanderson Blood 2007 110: 2041-2048. Prepublished online May 29, 2007; DOI 10.1182/blood-2007-04-082495 [Abstract] [Full Text] [PDF]   Targeted cancer therapy with a novel low-dose rate -emitting radioimmunoconjugate Jostein Dahle, Jørgen Borrebæk, Thora J. Jonasdottir, Anne Kristine Hjelmerud, Katrine B. Melhus, Øyvind S. Bruland, Oliver W. Press, and Roy H. Larsen Blood 2007 110: 2049-2056. Prepublished online May 29, 2007; DOI 10.1182/blood-2007-01-066803 [Abstract] [Full Text] [PDF]   Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo Min H. Kang, Yun Hee Kang, Barbara Szymanska, Urszula Wilczynska-Kalak, Michael A. Sheard, Theresa M. Harned, Richard B. Lock, and C. Patrick Reynolds Blood 2007 110: 2057-2066. Prepublished online May 29, 2007; DOI 10.1182/blood-2007-03-080325 [Abstract] [Full Text] [PDF]   BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms Samir Parekh, Jose M. Polo, Rita Shaknovich, Przemyslaw Juszczynski, Paola Lev, Stella M. Ranuncolo, Yingnan Yin, Ulf Klein, Giorgio Cattoretti, Riccardo Dalla Favera, Margaret A. Shipp, and Ari Melnick Blood 2007 110: 2067-2074. Prepublished online June 1, 2007; DOI 10.1182/blood-2007-01-069575 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]   Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia Lisheng Wang, Jie Wang, Bradley W. Blaser, Anne-Marie Duchemin, Donna F. Kusewitt, Tom Liu, Michael A. Caligiuri, and Roger Briesewitz Blood 2007 110: 2075-2083. Prepublished online May 30, 2007; DOI 10.1182/blood-2007-02-071266 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway Beat C. Bornhauser, Laura Bonapace, Dan Lindholm, Rodrigo Martinez, Gunnar Cario, Martin Schrappe, Felix K. Niggli, Beat W. Schäfer, and Jean-Pierre Bourquin Blood 2007 110: 2084-2091. Prepublished online May 30, 2007; DOI 10.1182/blood-2006-12-060970 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism Xin-Yan Pei, Yun Dai, Sarah Tenorio, Jianghua Lu, Hisashi Harada, Paul Dent, and Steven Grant Blood 2007 110: 2092-2101. Prepublished online May 31, 2007; DOI 10.1182/blood-2007-04-083204 [Abstract] [Full Text] [PDF]   Farnesyl transferase inhibitor resistance probed by target mutagenesis Tal Raz, Valentina Nardi, Mohammad Azam, Jorge Cortes, and George Q. Daley Blood 2007 110: 2102-2109. Prepublished online May 29, 2007; DOI 10.1182/blood-2006-12-064907 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Negative regulation of the SH2-homology–containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoprotein Jihua Cheng, Andre R. Kydd, Koichi Nakase, Kristin M. Noonan, Akikazu Murakami, Hong Tao, Markryan Dwyer, Chen Xu, Quan Zhu, and Wayne A. Marasco Blood 2007 110: 2110-2120. Prepublished online May 31, 2007; DOI 10.1182/blood-2006-11-058388 [Abstract] [Full Text] [PDF]   Nuclear CD40 interacts with c-Rel and enhances proliferation in aggressive B-cell lymphoma Hai-Jun Zhou, Lan V. Pham, Archito T. Tamayo, Yen-Chiu Lin-Lee, Lingchen Fu, Linda C. Yoshimura, and Richard J. Ford Blood 2007 110: 2121-2127. Prepublished online June 13, 2007; DOI 10.1182/blood-2007-02-073080 [Abstract] [Full Text] [PDF]   Brief report  Incidence and clinical implications of GATA1 mutations in newborns with Down syndrome Sharon R. Pine, Qianxu Guo, Changhong Yin, Somasundaram Jayabose, Charlotte M. Druschel, and Claudio Sandoval Blood 2007 110: 2128-2131. Prepublished online June 18, 2007; DOI 10.1182/blood-2007-01-069542 [Abstract] [Full Text] [PDF]   RED CELLS: Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum Sean C. Murphy, Sebastian Fernandez-Pol, Paul H. Chung, S. N. Prasanna Murthy, Stephen B. Milne, Marcela Salomao, H. Alex Brown, Jon W. Lomasney, Narla Mohandas, and Kasturi Haldar Blood 2007 110: 2132-2139. Prepublished online May 25, 2007; DOI 10.1182/blood-2007-04-083873 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   HIF–prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques Matthew M. Hsieh, N. Seth Linde, Aisha Wynter, Mark Metzger, Carol Wong, Ingrid Langsetmo, Al Lin, Reginald Smith, Griffin P. Rodgers, Robert E. Donahue, Stephen J. Klaus, and John F. Tisdale Blood 2007 110: 2140-2147. Prepublished online June 8, 2007; DOI 10.1182/blood-2007-02-073254 [Abstract] [Full Text] [PDF]   Mosaicism due to myeloid lineage–restricted loss of heterozygosity as cause of spontaneous Rh phenotype splitting Günther F. Körmöczi, Eva-Maria Dauber, Oskar A. Haas, Tobias J. Legler, Frederik B. Clausen, Gerhard Fritsch, Markus Raderer, Christoph Buchta, Andreas L. Petzer, Diether Schönitzer, Wolfgang R. Mayr, and Christoph Gassner Blood 2007 110: 2148-2157. Prepublished online May 30, 2007; DOI 10.1182/blood-2007-01-068106 [Abstract] [Full Text] [PDF]   Point mutations involved in red cell stomatocytosis convert the electroneutral anion exchanger 1 to a nonselective cation conductance Hélène Guizouarn, Sonia Martial, Nicole Gabillat, and Franck Borgese Blood 2007 110: 2158-2165. Prepublished online June 6, 2007; DOI 10.1182/blood-2006-12-063420 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin José Villagra, Sruti Shiva, Lori A. Hunter, Roberto F. Machado, Mark T. Gladwin, and Gregory J. Kato Blood 2007 110: 2166-2172. Prepublished online May 29, 2007; DOI 10.1182/blood-2006-12-061697 [Abstract] [Full Text] [PDF] [Supplemental Tables]   Hypoxic stress underlies defects in erythroblast islands in the Rb-null mouse Benjamin T. Spike, Benjamin C. Dibling, and Kay F. Macleod Blood 2007 110: 2173-2181. Prepublished online June 8, 2007; DOI 10.1182/blood-2007-01-069104 [Abstract] [Full Text] [PDF]   Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4 Lan Lin, Erika V. Valore, Elizabeta Nemeth, Julia B. Goodnough, Victoria Gabayan, and Tomas Ganz Blood 2007 110: 2182-2189. Prepublished online May 31, 2007; DOI 10.1182/blood-2007-04-087593 [Abstract] [Full Text] [PDF]   Brief report  Factor H–mediated cell surface protection from complement is critical for the survival of PNH erythrocytes Viviana P. Ferreira and Michael K. Pangburn Blood 2007 110: 2190-2192. Prepublished online June 6, 2007; DOI 10.1182/blood-2007-04-083170 [Abstract] [Full Text] [PDF]   Brief report  A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove Melanie J. Percy, Paul W. Furlow, Philip A. Beer, Terence R. J. Lappin, Mary Frances McMullin, and Frank S. Lee Blood 2007 110: 2193-2196. 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