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Receive this page by email each issue: [Sign up for eTOCs] Other Issues: August 15 2008; 112 (4)   [Index by Author]  [Cover Caption]  [Complete Inside Blood PDF]         INSIDE BLOOD        ASH 50TH ANNIVERSARY REVIEW        PLENARY PAPERS        REVIEW IN TRANSLATIONAL HEMATOLOGY        CLINICAL TRIALS AND OBSERVATIONS        HEMATOPOIESIS AND STEM CELLS        HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY        IMMUNOBIOLOGY        NEOPLASIA        PHAGOCYTES        RED CELLS        TRANSPLANTATION        CORRESPONDENCE        ERRATA Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: A freeway to stem cells? Alois Gratwohl and Aleksandra Wodnar-Filipowicz Blood 2008 112: 923-924. [Full Text] [PDF]   Further progress in CLL therapy Emili Montserrat Blood 2008 112: 924-925. [Full Text] [PDF]   "Spare-spleen-uximab" for chronic ITP Theodore E. Warkentin and Donald M. Arnold Blood 2008 112: 925-926. [Full Text] [PDF]   VWF secretion: what's in a name? Jill Johnsen and José A. López Blood 2008 112: 926-927. [Full Text] [PDF]   ITP three R's: regulation, routing, rituximab John W. Semple Blood 2008 112: 927-928. [Full Text] [PDF]   Ah receptor: xenobiotic response meets inflammation Qiang Ma Blood 2008 112: 928-929. [Full Text] [PDF]   Teasing out monocyte trafficking mechanisms Christopher V. Carman Blood 2008 112: 929-930. [Full Text] [PDF]   Fas, IL-7, and T cells: live and let die Franco Lori Blood 2008 112: 930-931. [Full Text] [PDF]   Erythropoiesis—once more HIF! Joachim Fandrey Blood 2008 112: 931-932. [Full Text] [PDF]   GVHD therapy: let there be light! Krishna V. Komanduri Blood 2008 112: 932-933. [Full Text] [PDF]   ASH 50TH ANNIVERSARY REVIEW: The phagocytes: neutrophils and monocytes David C. Dale, Laurence Boxer, and W. Conrad Liles Blood 2008 112: 935-945. [Abstract] [Full Text] [PDF]   Mast cells and mastocytosis Dean D. Metcalfe Blood 2008 112: 946-956. [Abstract] [Full Text] [PDF]   PLENARY PAPERS: Basal secretion of von Willebrand factor from human endothelial cells Jonathan P. Giblin, Lindsay J. Hewlett, and Matthew J. Hannah Blood 2008 112: 957-964. Prepublished online March 14, 2008; DOI 10.1182/blood-2007-12-130740 [Abstract] [Full Text] [PDF]   REVIEW IN TRANSLATIONAL HEMATOLOGY: Whole genome scanning as a cytogenetic tool in hematologic malignancies Jaroslaw P. Maciejewski and Ghulam J. Mufti Blood 2008 112: 965-974. Prepublished online May 27, 2008; DOI 10.1182/blood-2008-02-130435 [Abstract] [Full Text] [PDF]   CLINICAL TRIALS AND OBSERVATIONS: Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia Constantine S. Tam, Susan O'Brien, William Wierda, Hagop Kantarjian, Sijin Wen, Kim-Anh Do, Deborah A. Thomas, Jorge Cortes, Susan Lerner, and Michael J. Keating Blood 2008 112: 975-980. Prepublished online April 14, 2008; DOI 10.1182/blood-2008-02-140582 [Abstract] [Full Text] [PDF]   Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia Guillermo Garcia-Manero, Sarit Assouline, Jorge Cortes, Zeev Estrov, Hagop Kantarjian, Hui Yang, Willie M. Newsome, Wilson H. Miller, Jr, Caroline Rousseau, Ann Kalita, Claire Bonfils, Marja Dubay, Tracy-Ann Patterson, Zuomei Li, Jeffrey M. Besterman, Gregory Reid, Eric Laille, Robert E. Martell, and Mark Minden Blood 2008 112: 981-989. Prepublished online May 21, 2008; DOI 10.1182/blood-2007-10-115873 [Abstract] [Full Text] [PDF] [Supplemental Table]   Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction Steven M. Devine, Ravi Vij, Michael Rettig, Laura Todt, Kiley McGlauchlen, Nicholas Fisher, Hollie Devine, Daniel C. Link, Gary Calandra, Gary Bridger, Peter Westervelt, and John F. DiPersio Blood 2008 112: 990-998. Prepublished online April 21, 2008; DOI 10.1182/blood-2007-12-130179 [Abstract] [Full Text] [PDF]   Rituximab efficacy and safety in adult splenectomy candidates with chronic immune thrombocytopenic purpura: results of a prospective multicenter phase 2 study Bertrand Godeau, Raphael Porcher, Olivier Fain, François Lefrère, Pierre Fenaux, Stéphane Cheze, Anne Vekhoff, Marie-Paule Chauveheid, Jerôme Stirnemann, Lionel Galicier, Emmanuelle Bourgeois, Stéphanie Haiat, Bruno Varet, Michel Leporrier, Thomas Papo, Mehdi Khellaf, Marc Michel, and Philippe Bierling Blood 2008 112: 999-1004. Prepublished online May 7, 2008; DOI 10.1182/blood-2008-01-131029 [Abstract] [Full Text] [PDF]   Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome–positive leukemia Kimmo Porkka, Perttu Koskenvesa, Tuija Lundán, Johanna Rimpiläinen, Satu Mustjoki, Richard Smykla, Robert Wild, Roger Luo, Montserrat Arnan, Benoit Brethon, Lydia Eccersley, Henrik Hjorth-Hansen, Martin Höglund, Hana Klamova, Håvar Knutsen, Suhag Parikh, Emmanuel Raffoux, Franz Gruber, Finella Brito-Babapulle, Hervé Dombret, Rafael F. Duarte, Erkki Elonen, Ron Paquette, C. Michel Zwaan, and Francis Y. F. Lee Blood 2008 112: 1005-1012. Prepublished online May 13, 2008; DOI 10.1182/blood-2008-02-140665 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement Danxin Wang, Huizi Chen, Kathryn M. Momary, Larisa H. Cavallari, Julie A. Johnson, and Wolfgang Sadée Blood 2008 112: 1013-1021. Prepublished online June 3, 2008; DOI 10.1182/blood-2008-03-144899 [Abstract] [Full Text] [PDF] [Supplemental Tables]   A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose Gregory M. Cooper, Julie A. Johnson, Taimour Y. Langaee, Hua Feng, Ian B. Stanaway, Ute I. Schwarz, Marylyn D. Ritchie, C. Michael Stein, Dan M. Roden, Joshua D. Smith, David L. Veenstra, Allan E. Rettie, and Mark J. Rieder Blood 2008 112: 1022-1027. Prepublished online June 5, 2008; DOI 10.1182/blood-2008-01-134247 [Abstract] [Full Text] [PDF] [Supplemental Table]   High expression of CD40 on B-cell precursor acute lymphoblastic leukemia blasts is an independent risk factor associated with improved survival and enhanced capacity to up-regulate the death receptor CD95 Anja Troeger, Ludmila Glouchkova, Birgit Ackermann, Gabriele Escherich, Roland Meisel, Helmut Hanenberg, Monique L. den Boer, Rob Pieters, Gritta E. Janka-Schaub, Ulrich Goebel, Hans-Juergen Laws, and Dagmar Dilloo Blood 2008 112: 1028-1034. Prepublished online June 13, 2008; DOI 10.1182/blood-2007-11-123315 [Abstract] [Full Text] [PDF]   Brief report  First thalidomide clinical trial in multiple myeloma: a decade Frits van Rhee, Madhav Dhodapkar, John D. Shaughnessy, Jr, Elias Anaissie, David Siegel, Antje Hoering, Jerome Zeldis, Bonnie Jenkins, Seema Singhal, Jayesh Mehta, John Crowley, Sundar Jagannath, and Bart Barlogie Blood 2008 112: 1035-1038. Prepublished online May 23, 2008; DOI 10.1182/blood-2008-02-140954 [Abstract] [Full Text] [PDF]   Brief report  EBV-positive immunodeficiency lymphoma after alemtuzumab-CHOP therapy for peripheral T-cell lymphoma Hanneke C. Kluin-Nelemans, Jules L. Coenen, James E. Boers, Gustaaf W. van Imhoff, and Stefano Rosati Blood 2008 112: 1039-1041. Prepublished online May 23, 2008; DOI 10.1182/blood-2008-02-138800 [Abstract] [Full Text] [PDF]   HEMATOPOIESIS AND STEM CELLS: Syndromic thrombocytopenia and predisposition to acute myelogenous leukemia caused by constitutional microdeletions on chromosome 21q Marwan Shinawi, Ayelet Erez, Deborah L. Shardy, Brendan Lee, Rizwan Naeem, George Weissenberger, A. Craig Chinault, Sau Wai Cheung, and Sharon E. Plon Blood 2008 112: 1042-1047. Prepublished online May 16, 2008; DOI 10.1182/blood-2008-01-135970 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figure]   B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells Robert Mansson, Sasan Zandi, Kristina Anderson, Inga-Lill Martensson, Sten Eirik W. Jacobsen, David Bryder, and Mikael Sigvardsson Blood 2008 112: 1048-1055. Prepublished online May 21, 2008; DOI 10.1182/blood-2007-11-125385 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis Mira T. Kassouf, Hedia Chagraoui, Paresh Vyas, and Catherine Porcher Blood 2008 112: 1056-1067. Prepublished online June 12, 2008; DOI 10.1182/blood-2007-12-128900 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Id2 intrinsically regulates lymphoid and erythroid development via interaction with different target proteins Ming Ji, Huajie Li, Hyung Chan Suh, Kimberly D. Klarmann, Yoshifumi Yokota, and Jonathan R. Keller Blood 2008 112: 1068-1077. Prepublished online June 3, 2008; DOI 10.1182/blood-2008-01-133504 [Abstract] [Full Text] [PDF]   HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY: Recruitment of T cells into bone marrow of ITP patients possibly due to elevated expression of VLA-4 and CX3CR1 Bob Olsson, Börje Ridell, Lena Carlsson, Stefan Jacobsson, and Hans Wadenvik Blood 2008 112: 1078-1084. Prepublished online June 2, 2008; DOI 10.1182/blood-2008-02-139402 [Abstract] [Full Text] [PDF]   Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients Francesca Santilli, Mario Romano, Antonio Recchiuti, Alfredo Dragani, Angela Falco, Gianfranco Lessiani, Francesca Fioritoni, Stefano Lattanzio, Domenico Mattoscio, Raimondo De Cristofaro, Bianca Rocca, and Giovanni Davì Blood 2008 112: 1085-1090. Prepublished online June 9, 2008; DOI 10.1182/blood-2007-11-123091 [Abstract] [Full Text] [PDF]   Immune complexes formed following the binding of anti–platelet factor 4 (CXCL4) antibodies to CXCL4 stimulate human neutrophil activation and cell adhesion Zhihua Xiao, Gian P. Visentin, Kannayakanahalli M. Dayananda, and Sriram Neelamegham Blood 2008 112: 1091-1100. Prepublished online June 6, 2008; DOI 10.1182/blood-2008-04-153288 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII–based clots Michael Neyman, Jamie Gewirtz, and Mortimer Poncz Blood 2008 112: 1101-1108. Prepublished online June 16, 2008; DOI 10.1182/blood-2008-04-152959 [Abstract] [Full Text] [PDF] [Supplemental Videos]   Deficiency of decay-accelerating factor and complement receptor 1–related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg David D. Kim, Takashi Miwa, Yuko Kimura, Reto A. Schwendener, Menno van Lookeren Campagne, and Wen-Chao Song Blood 2008 112: 1109-1119. Prepublished online June 4, 2008; DOI 10.1182/blood-2008-01-134304 [Abstract] [Full Text] [PDF]   PGE2 induces angiogenesis via MT1-MMP–mediated activation of the TGFβ/Alk5 signaling pathway Arántzazu Alfranca, Juan Manuel López-Oliva, Laura Genís, Dolores López-Maderuelo, Isabel Mirones, Dolores Salvado, Antonio J. Quesada, Alicia G. Arroyo, and Juan Miguel Redondo Blood 2008 112: 1120-1128. Prepublished online June 9, 2008; DOI 10.1182/blood-2007-09-112268 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways Chang Min Yoon, Bok Sil Hong, Hyung Geun Moon, Seyoung Lim, Pann-Ghill Suh, Yoon-Keun Kim, Chi-Bom Chae, and Yong Song Gho Blood 2008 112: 1129-1138. Prepublished online June 9, 2008; DOI 10.1182/blood-2007-11-125203 [Abstract] [Full Text] [PDF]   Src family tyrosine kinase Lyn mediates VWF/GPIb-IX–induced platelet activation via the cGMP signaling pathway Hong Yin, Junling Liu, Zhenyu Li, Michael C. Berndt, Clifford A. Lowell, and Xiaoping Du Blood 2008 112: 1139-1146. Prepublished online June 11, 2008; DOI 10.1182/blood-2008-02-140970 [Abstract] [Full Text] [PDF]   Brief report  Analysis of regulatory T-cell changes in patients with idiopathic thrombocytopenic purpura receiving B cell–depleting therapy with rituximab Roberto Stasi, Nichola Cooper, Giovanni Del Poeta, Elisa Stipa, Maria Laura Evangelista, Elisabetta Abruzzese, and Sergio Amadori Blood 2008 112: 1147-1150. Prepublished online March 28, 2008; DOI 10.1182/blood-2007-12-129262 [Abstract] [Full Text] [PDF]   Brief report  Nonclassical anti-C2 domain antibodies are present in patients with factor VIII inhibitors Shannon L. Meeks, John F. Healey, Ernest T. Parker, Rachel T. Barrow, and Pete Lollar Blood 2008 112: 1151-1153. Prepublished online May 21, 2008; DOI 10.1182/blood-2008-01-132639 [Abstract] [Full Text] [PDF]   Brief report  Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm Stefania Mitola, Emanuela Moroni, Cosetta Ravelli, German Andres, Mirella Belleri, and Marco Presta Blood 2008 112: 1154-1157. Prepublished online May 27, 2008; DOI 10.1182/blood-2007-09-111450 [Abstract] [Full Text] [PDF] [Supplemental Figures]   IMMUNOBIOLOGY: Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound B. Paige Lawrence, Michael S. Denison, Hermann Novak, Beth A. Vorderstrasse, Nathalie Harrer, Wolfgang Neruda, Claudia Reichel, and Maximilian Woisetschläger Blood 2008 112: 1158-1165. Prepublished online February 12, 2008; DOI 10.1182/blood-2007-08-109645 [Abstract] [Full Text] [PDF]   Critical but divergent roles for CD62L and CD44 in directing blood monocyte trafficking in vivo during inflammation Heping Xu, Ayyakkannu Manivannan, Isabel Crane, Rosemary Dawson, and Janet Liversidge Blood 2008 112: 1166-1174. Prepublished online April 7, 2008; DOI 10.1182/blood-2007-06-098327 [Abstract] [Full Text] [PDF]   CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion Brian Kavanagh, Shaun O'Brien, David Lee, Yafei Hou, Vivian Weinberg, Brian Rini, James P. Allison, Eric J. Small, and Lawrence Fong Blood 2008 112: 1175-1183. Prepublished online June 3, 2008; DOI 10.1182/blood-2007-11-125435 [Abstract] [Full Text] [PDF]   CD300a/c regulate type I interferon and TNF- secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands Xinsheng Ju, Martin Zenke, Derek N. J. Hart, and Georgina J. Clark Blood 2008 112: 1184-1194. Prepublished online June 5, 2008; DOI 10.1182/blood-2007-12-127951 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Priming of T cells to Fas-mediated proliferative signals by interleukin-7 Bence Rethi, Nancy Vivar, Stefano Sammicheli, Caroline Fluur, Nicolas Ruffin, Ann Atlas, Eva Rajnavolgyi, and Francesca Chiodi Blood 2008 112: 1195-1204. Prepublished online April 25, 2008; DOI 10.1182/blood-2007-12-126698 [Abstract] [Full Text] [PDF]   Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcRI, FcRIII, and FcRIV Veronique Minard-Colin, Yan Xiu, Jonathan C. Poe, Mayuka Horikawa, Cynthia M. Magro, Yasuhito Hamaguchi, Karen M. Haas, and Thomas F. Tedder Blood 2008 112: 1205-1213. Prepublished online May 21, 2008; DOI 10.1182/blood-2008-01-135160 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell–mediated effects on regulatory T cells Ehud Hauben, Silvia Gregori, Elena Draghici, Barbara Migliavacca, Stefano Olivieri, Maximilian Woisetschläger, and Maria Grazia Roncarolo Blood 2008 112: 1214-1222. Prepublished online June 11, 2008; DOI 10.1182/blood-2007-08-109843 [Abstract] [Full Text] [PDF]   Endoplasmic reticulum HSP90b1 (gp96, grp94) optimizes B-cell function via chaperoning integrin and TLR but not immunoglobulin Bei Liu and Zihai Li Blood 2008 112: 1223-1230. Prepublished online May 28, 2008; DOI 10.1182/blood-2008-03-143107 [Abstract] [Full Text] [PDF]   Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses Cagan Gurer, Till Strowig, Fabienne Brilot, Maggi Pack, Christine Trumpfheller, Frida Arrey, Chae Gyu Park, Ralph M. Steinman, and Christian Münz Blood 2008 112: 1231-1239. Prepublished online June 2, 2008; DOI 10.1182/blood-2008-03-148072 [Abstract] [Full Text] [PDF] [Supplemental Figures]   The cytoplasmic tail of CD45 is released from activated phagocytes and can act as an inhibitory messenger for T cells Stefanie Kirchberger, Otto Majdic, Stefan Blüml, Catharina Schrauf, Judith Leitner, Christopher Gerner, Wolfgang Paster, Nina Gundacker, Maria Sibilia, and Johannes Stöckl Blood 2008 112: 1240-1248. Prepublished online May 29, 2008; DOI 10.1182/blood-2008-02-138131 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Antigen-specific T-T interactions regulate CD4 T-cell expansion Julie Helft, Alexandra Jacquet, Nathalie T. Joncker, Isabelle Grandjean, Guillaume Dorothée, Adrien Kissenpfennig, Bernard Malissen, Polly Matzinger, and Olivier Lantz Blood 2008 112: 1249-1258. Prepublished online June 6, 2008; DOI 10.1182/blood-2007-09-114389 [Abstract] [Full Text] [PDF] [Supplemental Figures]   PILAR is a novel modulator of human T-cell expansion Eduardo Huarte, Juan R. Cubillos-Ruiz, Yolanda C. Nesbeth, Uciane K. Scarlett, Diana G. Martinez, Xavier A. Engle, William F. Rigby, Patricia A. Pioli, Paul M. Guyre, and Jose R. Conejo-Garcia Blood 2008 112: 1259-1268. Prepublished online June 12, 2008; DOI 10.1182/blood-2007-12-130773 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figure]   SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment Bo Huang, Zhang Lei, Gui-Mei Zhang, Dong Li, Chuanwang Song, Bo Li, Yanyan Liu, Ye Yuan, Jay Unkeless, Huabao Xiong, and Zuo-Hua Feng Blood 2008 112: 1269-1279. Prepublished online June 4, 2008; DOI 10.1182/blood-2008-03-147033 [Abstract] [Full Text] [PDF] [Supplemental Tables]   Endothelial CD47 interaction with SIRP is required for human T-cell transendothelial migration under shear flow conditions in vitro Michael Stefanidakis, Gail Newton, Winston Y. Lee, Charles A. Parkos, and Francis W. Luscinskas Blood 2008 112: 1280-1289. Prepublished online June 4, 2008; DOI 10.1182/blood-2008-01-134429 [Abstract] [Full Text] [PDF] [Supplemental Videos]   Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites Roshanak Tolouei Semnani, Priyanka Goel Venugopal, Cynthia A. Leifer, Sven Mostböck, Helen Sabzevari, and Thomas B. Nutman Blood 2008 112: 1290-1298. Prepublished online June 9, 2008; DOI 10.1182/blood-2008-04-149856 [Abstract] [Full Text] [PDF]   The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways Alexandra A. Lambert, Caroline Gilbert, Manon Richard, André D. Beaulieu, and Michel J. Tremblay Blood 2008 112: 1299-1307. Prepublished online June 9, 2008; DOI 10.1182/blood-2008-01-136473 [Abstract] [Full Text] [PDF]   Inflammation-associated lysophospholipids as ligands for CD1d-restricted T cells in human cancer David H. Chang, Haiteng Deng, Phillip Matthews, Joseph Krasovsky, Govind Ragupathi, Radek Spisek, Amitabha Mazumder, David H. Vesole, Sundar Jagannath, and Madhav V. Dhodapkar Blood 2008 112: 1308-1316. Prepublished online June 5, 2008; DOI 10.1182/blood-2008-04-149831 [Abstract] [Full Text] [PDF]   Long-term expansion of effector/memory V2– T cells is a specific blood signature of CMV infection Vincent Pitard, David Roumanes, Xavier Lafarge, Lionel Couzi, Isabelle Garrigue, Marie-Edith Lafon, Pierre Merville, Jean-François Moreau, and Julie Déchanet-Merville Blood 2008 112: 1317-1324. Prepublished online June 6, 2008; DOI 10.1182/blood-2008-01-136713 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Brief report  Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura Jin Yu, Susanne Heck, Vivek Patel, Jared Levan, Yu Yu, James B. Bussel, and Karina Yazdanbakhsh Blood 2008 112: 1325-1328. Prepublished online April 17, 2008; DOI 10.1182/blood-2008-01-135335 [Abstract] [Full Text] [PDF]   NEOPLASIA: Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu Yu-Tzu Tai, Myles Dillon, Weihua Song, Merav Leiba, Xian-Feng Li, Peter Burger, Alfred I. Lee, Klaus Podar, Teru Hideshima, Audie G. Rice, Anne van Abbema, Lynne Jesaitis, Ingrid Caras, Debbie Law, Edie Weller, Wanling Xie, Paul Richardson, Nikhil C. Munshi, Claire Mathiot, Hervé Avet-Loiseau, Daniel E. H. Afar, and Kenneth C. Anderson Blood 2008 112: 1329-1337. Prepublished online September 28, 2007; DOI 10.1182/blood-2007-08-107292 [Abstract] [Full Text] [PDF] [Supplemental Figures][Notice of concern][Updated Notice of Concern]   Dexamethasone-induced apoptotic mechanisms in myeloma cells investigated by analysis of mutant glucocorticoid receptors Sanjai Sharma and Alan Lichtenstein Blood 2008 112: 1338-1345. Prepublished online May 30, 2008; DOI 10.1182/blood-2007-11-124156 [Abstract] [Full Text] [PDF]   Validation of PDGFRβ and c-Src tyrosine kinases as tumor/vessel targets in patients with multiple myeloma: preclinical efficacy of the novel, orally available inhibitor dasatinib Addolorata Maria Luce Coluccia, Teresa Cirulli, Paola Neri, Domenica Mangieri, Maria Cristina Colanardi, Antonio Gnoni, Nicola Di Renzo, Franco Dammacco, Pierfrancesco Tassone, Domenico Ribatti, Carlo Gambacorti-Passerini, and Angelo Vacca Blood 2008 112: 1346-1356. Prepublished online June 4, 2008; DOI 10.1182/blood-2007-10-116590 [Abstract] [Full Text] [PDF]   Inactivating Icmt ameliorates K-RAS–induced myeloproliferative disease Annika M. Wahlstrom, Briony A. Cutts, Meng Liu, Annika Lindskog, Christin Karlsson, Anna-Karin M. Sjogren, Karin M. E. Andersson, Stephen G. Young, and Martin O. Bergo Blood 2008 112: 1357-1365. Prepublished online May 23, 2008; DOI 10.1182/blood-2007-06-094060 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse Heike Kroeger, Jaroslav Jelinek, Marcos R. H. Estécio, Rong He, Kimie Kondo, Woonbok Chung, Li Zhang, Lanlan Shen, Hagop M. Kantarjian, Carlos E. Bueso-Ramos, and Jean-Pierre J. Issa Blood 2008 112: 1366-1373. Prepublished online June 3, 2008; DOI 10.1182/blood-2007-11-126227 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials Wolfram Klapper, Monika Szczepanowski, Birgit Burkhardt, Hilmar Berger, Maciej Rosolowski, Stefan Bentink, Carsten Schwaenen, Swen Wessendorf, Rainer Spang, Peter Möller, Martin Leo Hansmann, Heinz-Wolfram Bernd, German Ott, Michael Hummel, Harald Stein, Markus Loeffler, Lorenz Trümper, Martin Zimmermann, Alfred Reiter, and Reiner Siebert, for the "Molecular Mechanisms in Malignant Lymphomas" Network Project of the Deutsche Krebshilfe Blood 2008 112: 1374-1381. Prepublished online May 28, 2008; DOI 10.1182/blood-2008-01-136465 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia Steven W. Paugh, Barbara S. Paugh, Mohamed Rahmani, Dmitri Kapitonov, Jorge A. Almenara, Tomasz Kordula, Sheldon Milstien, Jeffrey K. Adams, Robert E. Zipkin, Steven Grant, and Sarah Spiegel Blood 2008 112: 1382-1391. Prepublished online May 29, 2008; DOI 10.1182/blood-2008-02-138958 [Abstract] [Full Text] [PDF]   t(8;21)(q22;q22) fusion proteins preferentially bind to duplicated AML1/RUNX1 DNA-binding sequences to differentially regulate gene expression Akiko J. Okumura, Luke F. Peterson, Fumihiko Okumura, Anita Boyapati, and Dong-Er Zhang Blood 2008 112: 1392-1401. Prepublished online May 29, 2008; DOI 10.1182/blood-2007-11-124735 [Abstract] [Full Text] [PDF] [Supplemental Methods, Table, and Figures]   JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders Isabelle Plo, Mayuka Nakatake, Laurent Malivert, Jean-Pierre de Villartay, Stéphane Giraudier, Jean-Luc Villeval, Lisa Wiesmuller, and William Vainchenker Blood 2008 112: 1402-1412. Prepublished online May 30, 2008; DOI 10.1182/blood-2008-01-134114 [Abstract] [Full Text] [PDF]   Up-regulation of WRN and DNA ligase III in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks Annahita Sallmyr, Alan E. Tomkinson, and Feyruz V. Rassool Blood 2008 112: 1413-1423. Prepublished online June 4, 2008; DOI 10.1182/blood-2007-07-104257 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines Daniela Buglio, Georgios V. Georgakis, Shino Hanabuchi, Kazuhiko Arima, Noor M. Khaskhely, Yong-Jun Liu, and Anas Younes Blood 2008 112: 1424-1433. Prepublished online June 9, 2008; DOI 10.1182/blood-2008-01-133769 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Quantitative trait loci associated with susceptibility to therapy-related acute murine promyelocytic leukemia in hCG-PML/RARA transgenic mice Ryan K. Funk, Taylor J. Maxwell, Masayo Izumi, Deepa Edwin, Friederike Kreisel, Timothy J. Ley, James M. Cheverud, and Timothy A. Graubert Blood 2008 112: 1434-1442. Prepublished online June 13, 2008; DOI 10.1182/blood-2008-01-132084 [Abstract] [Full Text] [PDF] [Supplemental Tables]   The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes Aditya Veldurthy, Michaela Patz, Susanne Hagist, Christian P. Pallasch, Clemens-Martin Wendtner, Michael Hallek, and Günter Krause Blood 2008 112: 1443-1452. Prepublished online June 12, 2008; DOI 10.1182/blood-2007-11-123984 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figure]   PHAGOCYTES: Essential role of nuclear factor-B for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes Marcos Luengo-Blanco, Carolina Prando, Jacinta Bustamante, Walmir Cutrim Aragão-Filho, Paulo Vitor Soeiro Pereira, Jussara Rehder, Carolyn Padden, Jean-Laurent Casanova, Peter E. Newburger, and Antonio Condino-Neto Blood 2008 112: 1453-1460. Prepublished online June 3, 2008; DOI 10.1182/blood-2007-07-099267 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Neutrophil secretion products pave the way for inflammatory monocytes Oliver Soehnlein, Alma Zernecke, Einar E. Eriksson, Antonio Gigliotti Rothfuchs, Christine T. Pham, Heiko Herwald, Kiril Bidzhekov, Martin E. Rottenberg, Christian Weber, and Lennart Lindbom Blood 2008 112: 1461-1471. Prepublished online May 19, 2008; DOI 10.1182/blood-2008-02-139634 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Leukocyte trafficking in a mouse model for leukocyte adhesion deficiency II/congenital disorder of glycosylation IIc Sviatlana Yakubenia, David Frommhold, Dirk Schölch, Christina C. Hellbusch, Christian Körner, Björn Petri, Claire Jones, Ute Ipe, M. Gabriele Bixel, Robert Krempien, Markus Sperandio, and Martin K. Wild Blood 2008 112: 1472-1481. Prepublished online June 9, 2008; DOI 10.1182/blood-2008-01-132035 [Abstract] [Full Text] [PDF] [Supplemental Figure]   RED CELLS: The microenvironment for erythropoiesis is regulated by HIF-2 through VCAM-1 in endothelial cells Toshiharu Yamashita, Osamu Ohneda, Ai Sakiyama, Fumiko Iwata, Kinuko Ohneda, and Yoshiaki Fujii-Kuriyama Blood 2008 112: 1482-1492. Prepublished online May 1, 2008; DOI 10.1182/blood-2007-11-122648 [Abstract] [Full Text] [PDF]   Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation Mondira Kundu, Tullia Lindsten, Chia-Ying Yang, Junmin Wu, Fangping Zhao, Ji Zhang, Mary A. Selak, Paul A. Ney, and Craig B. Thompson Blood 2008 112: 1493-1502. Prepublished online June 6, 2008; DOI 10.1182/blood-2008-02-137398 [Abstract] [Full Text] [PDF]   Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver Léon Kautz, Delphine Meynard, Annabelle Monnier, Valérie Darnaud, Régis Bouvet, Rui-Hong Wang, Chiuxia Deng, Sophie Vaulont, Jean Mosser, Hélène Coppin, and Marie-Paule Roth Blood 2008 112: 1503-1509. Prepublished online June 6, 2008; DOI 10.1182/blood-2008-03-143354 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Brief report  Impaired CD163-mediated hemoglobin-scavenging and severe toxic symptoms in patients treated with gemtuzumab ozogamicin Maciej Bogdan Maniecki, Henrik Hasle, Lennart Friis-Hansen, Birgitte Lausen, Ove Juul Nielsen, Knud Bendix, Søren Kragh Moestrup, and Holger Jon Møller Blood 2008 112: 1510-1514. Prepublished online June 11, 2008; DOI 10.1182/blood-2007-09-114165 [Abstract] [Full Text] [PDF] [Supplemental Figure]   TRANSPLANTATION: Extracorporeal photopheresis reverses experimental graft-versus-host disease through regulatory T cells Erin Gatza, Clare E. Rogers, Shawn G. Clouthier, Kathleen P. Lowler, Isao Tawara, Chen Liu, Pavan Reddy, and James L. M. Ferrara Blood 2008 112: 1515-1521. Prepublished online April 14, 2008; DOI 10.1182/blood-2007-11-125542 [Abstract] [Full Text] [PDF] [Supplemental Table and Figure]   Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation Kai Sun, Minghui Li, Thomas J. Sayers, Lisbeth A. Welniak, and William J. Murphy Blood 2008 112: 1522-1529. Prepublished online June 6, 2008; DOI 10.1182/blood-2008-03-143461 [Abstract] [Full Text] [PDF]   Murine neonates develop vigorous in vivo cytotoxic and Th1/Th2 responses upon exposure to low doses of NIMA-like alloantigens Shannon J. Opiela, Robert B. Levy, and Becky Adkins Blood 2008 112: 1530-1538. Prepublished online June 6, 2008; DOI 10.1182/blood-2007-08-106500 [Abstract] [Full Text] [PDF]   Brief report  Change in plasma tumor necrosis factor receptor 1 levels in the first week after myeloablative allogeneic transplantation correlates with severity and incidence of GVHD and survival Sung W. Choi, Carrie L. Kitko, Thomas Braun, Sophie Paczesny, Gregory Yanik, Shin Mineishi, Oleg Krijanovski, Dawn Jones, Joel Whitfield, Kenneth Cooke, Raymond J. Hutchinson, James L. M. Ferrara, and John E. Levine Blood 2008 112: 1539-1542. Prepublished online May 23, 2008; DOI 10.1182/blood-2008-02-138867 [Abstract] [Full Text] [PDF]   CORRESPONDENCE: Making business out of patients? Pablo Menendez Blood 2008 112: 1543. [Full Text] [PDF]   Statins inhibit human APC function: implications for the treatment of GVHD Alexander Shimabukuro-Vornhagen, Tanja Liebig, and Michael von Bergwelt-Baildon Blood 2008 112: 1544-1545. [Full Text] [PDF]   ERRATA: Piper et al., CXCL10-CXCR3 interactions play an important role in the pathogenesis of acute graft-versus-host disease in the skin following allogeneic stem-cell transplantation. Blood. 2007;110:3827-3832. Blood 2008 112: 1546. [Full Text] [PDF]   Ekker. The three musketeers of HSC development. Blood. 2008;111:4834-4835. Blood 2008 112: 1546. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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