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Receive this page by email each issue: [Sign up for eTOCs] Other Issues:   April 30 2009; 113 (18)   [Index by Author]  [Cover Caption] [Complete Inside Blood PDF]         INSIDE BLOOD        CLINICAL TRIALS AND OBSERVATIONS        HEMATOPOIESIS AND STEM CELLS        IMMUNOBIOLOGY        LYMPHOID NEOPLASIA        MYELOID NEOPLASIA        THROMBOSIS AND HEMOSTASIS        TRANSPLANTATION        VASCULAR BIOLOGY        CORRESPONDENCE        ERRATUM Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: Closer to the truth in AML Jacob M. Rowe Blood 2009 113: 4129-4130. [Full Text] [PDF]   The changing definition of CLL Gerald E. Marti Blood 2009 113: 4130-4131. [Full Text] [PDF]   Mesenchymally "stemming" angiogenesis Michael A. Matthay Blood 2009 113: 4131-4132. [Full Text] [PDF]   Hiding from ABT-737 in lymph nodes Anthony Letai Blood 2009 113: 4132-4133. [Full Text] [PDF]   MicroRNAs to know in Waldenström macroglobulinemia Angelo Vacca and Franco Dammacco Blood 2009 113: 4133-4134. [Full Text] [PDF]   How can fibrinolysis induce cell death? Margarethe Geiger Blood 2009 113: 4134-4135. [Full Text] [PDF]   Lymphangiogenesis factors: a target for therapy? Arjan W. Griffioen Blood 2009 113: 4135-4136. [Full Text] [PDF]   CLINICAL TRIALS AND OBSERVATIONS: Lenalidomide, adriamycin, and dexamethasone (RAD) in patients with relapsed and refractory multiple myeloma: a report from the German Myeloma Study Group DSMM (Deutsche Studiengruppe Multiples Myelom) Stefan Knop, Christian Gerecke, Peter Liebisch, Max S. Topp, Uwe Platzbecker, Orhan Sezer, Christina Vollmuth, Karina Falk, Axel Glasmacher, Uwe Maeder, Hermann Einsele, and Ralf C. Bargou Blood 2009 113: 4137-4143. Prepublished online January 30, 2009; DOI 10.1182/blood-2008-10-184135 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Mature results of the M. D. Anderson Cancer Center risk-adapted transplantation strategy in mantle cell lymphoma Constantine S. Tam, Roland Bassett, Celina Ledesma, Martin Korbling, Amin Alousi, Chitra Hosing, Partow Kebraei, Robyn Harrell, Gabriela Rondon, Sergio A. Giralt, Paolo Anderlini, Uday Popat, Barbara Pro, Barry Samuels, Frederick Hagemeister, L. Jeffrey Medeiros, Richard E. Champlin, and Issa F. Khouri Blood 2009 113: 4144-4152. Prepublished online January 23, 2009; DOI 10.1182/blood-2008-10-184200 [Abstract] [Full Text] [PDF]   Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL) Renato Bassan, Orietta Spinelli, Elena Oldani, Tamara Intermesoli, Manuela Tosi, Barbara Peruta, Giuseppe Rossi, Erika Borlenghi, Enrico M. Pogliani, Elisabetta Terruzzi, Pietro Fabris, Vincenzo Cassibba, Giorgio Lambertenghi-Deliliers, Agostino Cortelezzi, Alberto Bosi, Giacomo Gianfaldoni, Fabio Ciceri, Massimo Bernardi, Andrea Gallamini, Daniele Mattei, Eros Di Bona, Claudio Romani, Anna Maria Scattolin, Tiziano Barbui, and Alessandro Rambaldi Blood 2009 113: 4153-4162. Prepublished online January 13, 2009; DOI 10.1182/blood-2008-11-185132 [Abstract] [Full Text] [PDF] [Supplemental Figures]   International prognostic scoring system for Waldenström macroglobulinemia Pierre Morel, Alain Duhamel, Paolo Gobbi, Meletios A. Dimopoulos, Madhav V. Dhodapkar, Jason McCoy, John Crowley, Enrique M. Ocio, Ramon Garcia-Sanz, Steven P. Treon, Veronique Leblond, Robert A. Kyle, Bart Barlogie, and Giampaolo Merlini Blood 2009 113: 4163-4170. Prepublished online February 5, 2009; DOI 10.1182/blood-2008-08-174961 [Abstract] [Full Text] [PDF] [Supplemental Appendices and Table]   The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during disease course Constantine S. Tam, Lynne V. Abruzzo, Katherine I. Lin, Jorge Cortes, Alice Lynn, Michael J. Keating, Deborah A. Thomas, Sherry Pierce, Hagop Kantarjian, and Srdan Verstovsek Blood 2009 113: 4171-4178. Prepublished online January 8, 2009; DOI 10.1182/blood-2008-09-178541 [Abstract] [Full Text] [PDF]   Age and acute myeloid leukemia: real world data on decision to treat and outcomes from the Swedish Acute Leukemia Registry Gunnar Juliusson, Petar Antunovic, Åsa Derolf, Sören Lehmann, Lars Möllgård, Dick Stockelberg, Ulf Tidefelt, Anders Wahlin, and Martin Höglund Blood 2009 113: 4179-4187. Prepublished online November 13, 2008; DOI 10.1182/blood-2008-07-172007 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   B-cell count and survival: differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome Tait D. Shanafelt, Neil E. Kay, Greg Jenkins, Timothy G. Call, Clive S. Zent, Diane F. Jelinek, William G. Morice, Justin Boysen, Liam Zakko, Susan Schwager, Susan L. Slager, and Curtis A. Hanson Blood 2009 113: 4188-4196. Prepublished online November 17, 2008; DOI 10.1182/blood-2008-09-176149 [Abstract] [Full Text] [PDF]   HEMATOPOIESIS AND STEM CELLS: Concentration-dependent inhibition of angiogenesis by mesenchymal stem cells Keishi Otsu, Shonit Das, Sandra D. Houser, Sadiqa K. Quadri, Sunita Bhattacharya, and Jahar Bhattacharya Blood 2009 113: 4197-4205. Prepublished online November 25, 2008; DOI 10.1182/blood-2008-09-176198 [Abstract] [Full Text] [PDF] [Supplemental Figures]   IMMUNOBIOLOGY: Impaired maintenance of naturally acquired T-cell memory to the meningococcus in patients with B-cell immunodeficiency Begonia Morales-Aza, Sarah J. Glennie, Tomaz Pereira Garcez, Victoria Davenport, Sarah L. Johnston, Neil A. Williams, and Robert S. Heyderman Blood 2009 113: 4206-4212. Prepublished online February 6, 2009; DOI 10.1182/blood-2008-08-171587 [Abstract] [Full Text] [PDF]   Th-1 polarization is regulated by dendritic-cell comparison of MHC class I and class II antigens William K. Decker, Dongxia Xing, Sufang Li, Simon N. Robinson, Hong Yang, David Steiner, Krishna V. Komanduri, and Elizabeth J. Shpall Blood 2009 113: 4213-4223. Prepublished online January 26, 2009; DOI 10.1182/blood-2008-10-185470 [Abstract] [Full Text] [PDF]   A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration Clive S. McKimmie, Mark Moore, Alasdair R. Fraser, Thomas Jamieson, Damo Xu, Claire Burt, Nick I. Pitman, Robert J. Nibbs, Iain B. McInnes, Foo Y. Liew, and Gerard J. Graham Blood 2009 113: 4224-4231. Prepublished online February 6, 2009; DOI 10.1182/blood-2008-08-174698 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Human plasmacytoid dendritic cells are unresponsive to bacterial stimulation and require a novel type of cooperation with myeloid dendritic cells for maturation Diego Piccioli, Chiara Sammicheli, Simona Tavarini, Sandra Nuti, Elisabetta Frigimelica, Andrea G.O. Manetti, Annalisa Nuccitelli, Susanna Aprea, Sara Valentini, Erica Borgogni, Andreas Wack, and Nicholas M. Valiante Blood 2009 113: 4232-4239. Prepublished online January 27, 2009; DOI 10.1182/blood-2008-10-186890 [Abstract] [Full Text] [PDF] [Supplemental Figures]   IL-17–producing human peripheral regulatory T cells retain suppressive function Gaëlle Beriou, Cristina M. Costantino, Charles W. Ashley, Li Yang, Vijay K. Kuchroo, Clare Baecher-Allan, and David A. Hafler Blood 2009 113: 4240-4249. Prepublished online January 26, 2009; DOI 10.1182/blood-2008-10-183251 [Abstract] [Full Text] [PDF]   Limited ability of humoral immune responses in control of viremia during infection with SIVsmmD215 strain Thaidra Gaufin, Rajeev Gautam, Melissa Kasheta, Ruy Ribeiro, Erin Ribka, Mary Barnes, Melissa Pattison, Coty Tatum, Jeanne MacFarland, David Montefiori, Amitinder Kaur, Ivona Pandrea, and Cristian Apetrei Blood 2009 113: 4250-4261. Prepublished online January 23, 2009; DOI 10.1182/blood-2008-09-177741 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Antigen mRNA-transfected, allogeneic fibroblasts loaded with NKT-cell ligand confer antitumor immunity Shin-ichiro Fujii, Akira Goto, and Kanako Shimizu Blood 2009 113: 4262-4272. Prepublished online January 22, 2009; DOI 10.1182/blood-2008-08-176446 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Cognate CD4 help is essential for the reactivation and expansion of CD8 memory T cells directed against the hematopoietic cell–specific dominant minor histocompatibility antigen, H60 Su Jeong Ryu, Kyung Min Jung, Hyun Seung Yoo, Tae Woo Kim, Sol Kim, Jun Chang, and Eun Young Choi Blood 2009 113: 4273-4280. Prepublished online January 12, 2009; DOI 10.1182/blood-2008-09-181263 [Abstract] [Full Text] [PDF] [Supplemental Figure]   LYMPHOID NEOPLASIA: Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine Andreas Höglund, Lisa M. Nilsson, Linus Plym Forshell, Kirsteen H. Maclean, and Jonas A. Nilsson Blood 2009 113: 4281-4288. Prepublished online January 29, 2009; DOI 10.1182/blood-2008-10-183475 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells Claudia P. Miller, Sharmistha Rudra, Michael J. Keating, William G. Wierda, Michael Palladino, and Joya Chandra Blood 2009 113: 4289-4299. Prepublished online January 30, 2009; DOI 10.1182/blood-2008-08-174797 [Abstract] [Full Text] [PDF]   Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism Paola Secchiero, Elisabetta Melloni, Maria Grazia di Iasio, Mario Tiribelli, Erika Rimondi, Federica Corallini, Valter Gattei, and Giorgio Zauli Blood 2009 113: 4300-4308. Prepublished online February 3, 2009; DOI 10.1182/blood-2008-11-187708 [Abstract] [Full Text] [PDF]   CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf–mediated interactions with bone marrow stromal cells Yu-Tzu Tai, Ender Soydan, Weihua Song, Mariateresa Fulciniti, Kihyun Kim, Fangxin Hong, Xian-Feng Li, Peter Burger, Matthew J. Rumizen, Sabikun Nahar, Klaus Podar, Teru Hideshima, Nikhil C. Munshi, Giovanni Tonon, Ruben D. Carrasco, Daniel E. H. Afar, and Kenneth C. Anderson Blood 2009 113: 4309-4318. Prepublished online February 4, 2009; DOI 10.1182/blood-2008-10-183772 [Abstract] [Full Text] [PDF]   Bortezomib induces osteoblast differentiation via Wnt-independent activation of β-catenin/TCF signaling Ya-Wei Qiang, Bo Hu, Yu Chen, Ying Zhong, Bingyin Shi, Bart Barlogie, and John D. Shaughnessy, Jr Blood 2009 113: 4319-4330. Prepublished online February 4, 2009; DOI 10.1182/blood-2008-08-174300 [Abstract] [Full Text] [PDF]   Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma Dirk Hose, Thierry Rème, Tobias Meissner, Jérôme Moreaux, Anja Seckinger, Joe Lewis, Vladimir Benes, Axel Benner, Michael Hundemer, Thomas Hielscher, John D. Shaughnessy, Jr, Bart Barlogie, Kai Neben, Alwin Krämer, Jens Hillengass, Uta Bertsch, Anna Jauch, John De Vos, Jean-François Rossi, Thomas Möhler, Jonathon Blake, Jürgen Zimmermann, Bernard Klein, and Hartmut Goldschmidt Blood 2009 113: 4331-4340. Prepublished online January 26, 2009; DOI 10.1182/blood-2008-09-178350 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figure]   CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy Abdel Kareem Azab, Judith M. Runnels, Costas Pitsillides, Anne-Sophie Moreau, Feda Azab, Xavier Leleu, Xiaoying Jia, Renee Wright, Beatriz Ospina, Alicia L. Carlson, Clemens Alt, Nicholas Burwick, Aldo M. Roccaro, Hai T. Ngo, Mena Farag, Molly R. Melhem, Antonio Sacco, Nikhil C. Munshi, Teru Hideshima, Barrett J. Rollins, Kenneth C. Anderson, Andrew L. Kung, Charles P. Lin, and Irene M. Ghobrial Blood 2009 113: 4341-4351. Prepublished online January 12, 2009; DOI 10.1182/blood-2008-10-186668 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas Hans-Peter Gerber, May Kung-Sutherland, Ivan Stone, Carol Morris-Tilden, Jamie Miyamoto, Renee McCormick, Stephen C. Alley, Nicole Okeley, Brad Hayes, Francisco J. Hernandez-Ilizaliturri, Charlotte F. McDonagh, Paul J. Carter, Dennis Benjamin, and Iqbal S. Grewal Blood 2009 113: 4352-4361. Prepublished online January 15, 2009; DOI 10.1182/blood-2008-09-179143 [Abstract] [Full Text] [PDF] [Supplemental Table and Figure]   Aberrant splicing of folylpolyglutamate synthetase as a novel mechanism of antifolate resistance in leukemia Michal Stark, Chen Wichman, Irit Avivi, and Yehuda G. Assaraf Blood 2009 113: 4362-4369. Prepublished online January 8, 2009; DOI 10.1182/blood-2008-08-173799 [Abstract] [Full Text] [PDF] [Supplemental Materials and Methods]   PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation Pengrong Yan, Jing Fu, Zhaoxia Qu, Shirong Li, Takashi Tanaka, Michael J. Grusby, and Gutian Xiao Blood 2009 113: 4370-4380. Prepublished online January 8, 2009; DOI 10.1182/blood-2008-10-185660 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL Wendy R. Gordon, Monideepa Roy, Didem Vardar-Ulu, Megan Garfinkel, Marc R. Mansour, Jon C. Aster, and Stephen C. Blacklow Blood 2009 113: 4381-4390. Prepublished online December 15, 2008; DOI 10.1182/blood-2008-08-174748 [Abstract] [Full Text] [PDF] [Supplemental Figure]   microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia Aldo M. Roccaro, Antonio Sacco, Changzhong Chen, Judith Runnels, Xavier Leleu, Feda Azab, Abdel Kareem Azab, Xiaoying Jia, Hai T. Ngo, Molly R. Melhem, Nicholas Burwick, Lyuba Varticovski, Carl D. Novina, Barrett J. Rollins, Kenneth C. Anderson, and Irene M. Ghobrial Blood 2009 113: 4391-4402. Prepublished online December 12, 2008; DOI 10.1182/blood-2008-09-178228 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figure]   Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia Meike Vogler, Michael Butterworth, Aneela Majid, Renata J. Walewska, Xiao-Ming Sun, Martin J. S. Dyer, and Gerald M. Cohen Blood 2009 113: 4403-4413. Prepublished online November 13, 2008; DOI 10.1182/blood-2008-08-173310 [Abstract] [Full Text] [PDF] [Supplemental Figures]   MYELOID NEOPLASIA: Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesis Gordon Chan, Demetrios Kalaitzidis, Tatiana Usenko, Jeffery L. Kutok, Wentian Yang, M. Golam Mohi, and Benjamin G. Neel Blood 2009 113: 4414-4424. Prepublished online January 29, 2009; DOI 10.1182/blood-2008-10-182626 [Abstract] [Full Text] [PDF] [Supplemental Figures]   THROMBOSIS AND HEMOSTASIS: Fibrinogen variant BβD432A has normal polymerization but does not bind knob "B" Sheryl R. Bowley and Susan T. Lord Blood 2009 113: 4425-4430. Prepublished online December 15, 2008; DOI 10.1182/blood-2008-09-178178 [Abstract] [Full Text] [PDF] [Supplementary Table and Figure]   Caveolin-1–dependent apoptosis induced by fibrin degradation products Yi-He Guo, Irene Hernandez, Berend Isermann, Tae-bong Kang, Leonid Medved, Rashmi Sood, Edward J. Kerschen, Trudy Holyst, Michael W. Mosesson, and Hartmut Weiler Blood 2009 113: 4431-4439. Prepublished online December 12, 2008; DOI 10.1182/blood-2008-07-169433 [Abstract] [Full Text] [PDF]   TRANSPLANTATION: Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras Arnab Ghosh, Wolfgang Koestner, Martin Hapke, Verena Schlaphoff, Florian Länger, Rolf Baumann, Christian Koenecke, Markus Cornberg, Karl Welte, Bruce R. Blazar, and Martin G. Sauer Blood 2009 113: 4440-4448. Prepublished online January 30, 2009; DOI 10.1182/blood-2008-09-181677 [Abstract] [Full Text] [PDF]   Depletion of CD4 T cells enhances immunotherapy for neuroblastoma after syngeneic HSCT but compromises development of antitumor immune memory Weiqing Jing, Jill A. Gershan, and Bryon D. Johnson Blood 2009 113: 4449-4457. Prepublished online January 30, 2009; DOI 10.1182/blood-2008-11-190827 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Host natural killer T cells induce an interleukin-4–dependent expansion of donor CD4+CD25+Foxp3+ T regulatory cells that protects against graft-versus-host disease Asha B. Pillai, Tracy I. George, Suparna Dutt, and Samuel Strober Blood 2009 113: 4458-4467. Prepublished online February 12, 2009; DOI 10.1182/blood-2008-06-165506 [Abstract] [Full Text] [PDF] [Supplemental Figures]   VASCULAR BIOLOGY: Vascular endothelial growth factor-D transgenic mice show enhanced blood capillary density, improved postischemic muscle regeneration, and increased susceptibility to tumor formation Anna-Mari Kärkkäinen, Antti Kotimaa, Jenni Huusko, Ivana Kholova, Suvi Elina Heinonen, Anna Stefanska, Marike Hinke Dijkstra, Hanna Purhonen, Eveliina Hämäläinen, Petri Ilmari Mäkinen, Mikko Petri Turunen, and Seppo Ylä-Herttuala Blood 2009 113: 4468-4475. Prepublished online December 10, 2008; DOI 10.1182/blood-2008-07-171108 [Abstract] [Full Text] [PDF]   CORRESPONDENCE: Malignant stem cells in childhood ALL: the debate continues! Olaf Heidenreich and Josef Vormoor Blood 2009 113: 4476-4477. [Full Text] [PDF]   Stem cells in childhood acute lymphoblastic leukemia: identifying the most relevant targets for therapy Paraskevi Diamanti and Allison Blair Blood 2009 113: 4477. [Full Text] [PDF]   ERRATUM: Möricke et al. Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95. Blood. 2008;111:4477-4489. Blood 2009 113: 4478. [Full Text] [PDF]   Argyriou et al. Bortezomib-induced peripheral neuropathy in multiple myeloma: a comprehensive review of the literature. Blood. 2008;112:1593-1599. Blood 2009 113: 4478. [Full Text] [PDF]   Flowers et al. A multicenter prospective phase 2 randomized study of extracorporeal photopheresis for treatment of chronic graft-versus-host disease. Blood. 2008;112:2667-2674. Blood 2009 113: 4478. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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