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Receive this page by email each issue: [Sign up for eTOCs] Other Issues:   May 28 2009; 113 (22)   [Index by Author]  [Cover Caption] [Complete Inside Blood PDF]         INSIDE BLOOD        PLENARY PAPERS        HOW I TREAT        CLINICAL TRIALS AND OBSERVATIONS        GENE THERAPY        HEMATOPOIESIS AND STEM CELLS        IMMUNOBIOLOGY        LYMPHOID NEOPLASIA        MYELOID NEOPLASIA        PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS        PLATELETS AND THROMBOPOIESIS        RED CELLS, IRON, AND ERYTHROPOIESIS        THROMBOSIS AND HEMOSTASIS        TRANSFUSION MEDICINE        TRANSPLANTATION        VASCULAR BIOLOGY        CORRESPONDENCE Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: Be fruitful, multiply, and replenish José A. M. Borghans and Kiki Tesselaar Blood 2009 113: 5369-5370. [Full Text] [PDF]   Are all myelomas preceded by MGUS? Joan Bladé, Laura Rosiñol, and Ma Teresa Cibeira Blood 2009 113: 5370. [Full Text] [PDF]   Enolase-1 as a plasminogen receptor Edward F. Plow and Riku Das Blood 2009 113: 5371-5372. [Full Text] [PDF]   Where spectrin snuggles with ankyrin Philip S. Low Blood 2009 113: 5372-5373. [Full Text] [PDF]   A team player: the disintegrin domain of ADAMTS13 X. Long Zheng Blood 2009 113: 5373-5374. [Full Text] [PDF]   RTEs: lazy T-cell teenagers Pamela J. Fink Blood 2009 113: 5374-5375. [Full Text] [PDF]   Dll1 and Dll4: similar, but not the same Manfred Gessler Blood 2009 113: 5375-5376. [Full Text] [PDF]   PLENARY PAPERS: The structure of the ankyrin-binding site of β-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties Paul R. Stabach, Ivana Simonovic, Miranda A. Ranieri, Michael S. Aboodi, Thomas A. Steitz, Miljan Simonovic, and Jon S. Morrow Blood 2009 113: 5377-5384. Prepublished online January 23, 2009; DOI 10.1182/blood-2008-10-184291 [Abstract] [Full Text] [PDF] [Supplemental Tables, Figures, and Videos]   Structures of the spectrin-ankyrin interaction binding domains Jonathan J. Ipsaro, Lei Huang, and Alfonso Mondragón Blood 2009 113: 5385-5393. Prepublished online January 13, 2009; DOI 10.1182/blood-2008-10-184358 [Abstract] [Full Text] [PDF] [Supplemental Videos]   HOW I TREAT: How I treat symptomatic splenomegaly in patients with myelofibrosis Ruben A. Mesa Blood 2009 113: 5394-5400. Prepublished online March 30, 2009; DOI 10.1182/blood-2009-02-195974 [Abstract] [Full Text] [PDF]   CLINICAL TRIALS AND OBSERVATIONS: Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: the ADAGIO study Lucien Noens, Marie-Anne van Lierde, Robrecht De Bock, Gregor Verhoef, Pierre Zachée, Zwi Berneman, Philippe Martiat, Philippe Mineur, Koen Van Eygen, Karen MacDonald, Sabina De Geest, Tara Albrecht, and Ivo Abraham Blood 2009 113: 5401-5411. Prepublished online April 6, 2009; DOI 10.1182/blood-2008-12-196543 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study Ola Landgren, Robert A. Kyle, Ruth M. Pfeiffer, Jerry A. Katzmann, Neil E. Caporaso, Richard B. Hayes, Angela Dispenzieri, Shaji Kumar, Raynell J. Clark, Dalsu Baris, Robert Hoover, and S. Vincent Rajkumar Blood 2009 113: 5412-5417. Prepublished online January 29, 2009; DOI 10.1182/blood-2008-12-194241 [Abstract] [Full Text] [PDF]   A monoclonal gammopathy precedes multiple myeloma in most patients Brendan M. Weiss, Jude Abadie, Pramvir Verma, Robin S. Howard, and W. Michael Kuehl Blood 2009 113: 5418-5422. Prepublished online February 20, 2009; DOI 10.1182/blood-2008-12-195008 [Abstract] [Full Text] [PDF]   GENE THERAPY: Toward a stem cell gene therapy for breast cancer ZongYi Li, Ying Liu, Sebastian Tuve, Ye Xun, Xiaolong Fan, Liang Min, Qinghua Feng, Nancy Kiviat, Hans-Peter Kiem, Mary Leonora Disis, and André Lieber Blood 2009 113: 5423-5433. Prepublished online March 27, 2009; DOI 10.1182/blood-2008-10-187237 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures][Additional Supplemental Figures]   Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector–transduced CD34+ cells Yoo-Jin Kim, Yoon-Sang Kim, Andre Larochelle, Gabriel Renaud, Tyra G. Wolfsberg, Rima Adler, Robert E. Donahue, Peiman Hematti, Bum-Kee Hong, Jean Roayaei, Keiko Akagi, Janice M. Riberdy, Arthur W. Nienhuis, Cynthia E. Dunbar, and Derek A. Persons Blood 2009 113: 5434-5443. Prepublished online April 1, 2009; DOI 10.1182/blood-2008-10-185199 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   HEMATOPOIESIS AND STEM CELLS: Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation Jonathan Hoggatt, Pratibha Singh, Janardhan Sampath, and Louis M. Pelus Blood 2009 113: 5444-5455. Prepublished online March 26, 2009; DOI 10.1182/blood-2009-01-201335 [Abstract] [Full Text] [PDF] [Supplemental Table]   The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development Nicola K. Wilson, Diego Miranda-Saavedra, Sarah Kinston, Nicolas Bonadies, Samuel D. Foster, Fernando Calero-Nieto, Mark A. Dawson, Ian J. Donaldson, Stephanie Dumon, Jonathan Frampton, Rekin's Janky, Xiao-Hong Sun, Sarah A. Teichmann, Andrew J. Bannister, and Berthold Göttgens Blood 2009 113: 5456-5465. Prepublished online April 3, 2009; DOI 10.1182/blood-2009-01-200048 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Gfi1 integrates progenitor versus granulocytic transcriptional programming Shane R. Horman, Chinavenmeni S. Velu, Aditya Chaubey, Tristan Bourdeau, Jinfang Zhu, William E. Paul, Brian Gebelein, and H. Leighton Grimes Blood 2009 113: 5466-5475. Prepublished online April 3, 2009; DOI 10.1182/blood-2008-09-179747 [Abstract] [Full Text] [PDF]   Brief report  Generation of induced pluripotent stem cells from human blood Yuin-Han Loh, Suneet Agarwal, In-Hyun Park, Achia Urbach, Hongguang Huo, Garrett C. Heffner, Kitai Kim, Justine D. Miller, Kitwa Ng, and George Q. Daley Blood 2009 113: 5476-5479. Prepublished online March 18, 2009; DOI 10.1182/blood-2009-02-204800 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   IMMUNOBIOLOGY: Quantifying the development of the peripheral naive CD4+ T-cell pool in humans Iren Bains, Rustom Antia, Robin Callard, and Andrew J. Yates Blood 2009 113: 5480-5487. Prepublished online January 28, 2009; DOI 10.1182/blood-2008-10-184184 [Abstract] [Full Text] [PDF]   Maturation of mouse NK cells is a 4-stage developmental program Laura Chiossone, Julie Chaix, Nicolas Fuseri, Claude Roth, Eric Vivier, and Thierry Walzer Blood 2009 113: 5488-5496. Prepublished online February 20, 2009; DOI 10.1182/blood-2008-10-187179 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figure]   Desensitization to type I interferon in HIV-1 infection correlates with markers of immune activation and disease progression Gareth A. D. Hardy, Scott F. Sieg, Benigno Rodriguez, Wei Jiang, Robert Asaad, Michael M. Lederman, and Clifford V. Harding Blood 2009 113: 5497-5505. Prepublished online March 19, 2009; DOI 10.1182/blood-2008-11-190231 [Abstract] [Full Text] [PDF]   Notch1, Notch2, and Epstein-Barr virus–encoded nuclear antigen 2 signaling differentially affects proliferation and survival of Epstein-Barr virus–infected B cells Hella Kohlhof, Franziska Hampel, Reinhard Hoffmann, Helmut Burtscher, Ulrich H. Weidle, Michael Hölzel, Dirk Eick, Ursula Zimber-Strobl, and Lothar J. Strobl Blood 2009 113: 5506-5515. Prepublished online April 1, 2009; DOI 10.1182/blood-2008-11-190090 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Reciprocal responsiveness to interleukin-12 and interferon- specifies human CD8+ effector versus central memory T-cell fates Hilario J. Ramos, Ann M. Davis, Alexander G. Cole, John D. Schatzle, James Forman, and J. David Farrar Blood 2009 113: 5516-5525. Prepublished online March 18, 2009; DOI 10.1182/blood-2008-11-188458 [Abstract] [Full Text] [PDF] [Supplemental Figures]   LYMPHOID NEOPLASIA: Alcohol consumption and decreased risk of non-Hodgkin lymphoma: role of mTOR dysfunction Patrick R. Hagner, Krystyna Mazan-Mamczarz, Bojie Dai, Sharon Corl, X. Frank Zhao, and Ronald B. Gartenhaus Blood 2009 113: 5526-5535. Prepublished online March 17, 2009; DOI 10.1182/blood-2008-11-191783 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL Weimin Ci, Jose M. Polo, Leandro Cerchietti, Rita Shaknovich, Ling Wang, Shao Ning Yang, Kenny Ye, Pedro Farinha, Douglas E. Horsman, Randy D. Gascoyne, Olivier Elemento, and Ari Melnick Blood 2009 113: 5536-5548. Prepublished online March 23, 2009; DOI 10.1182/blood-2008-12-193037 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell–mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach Matthias Niedermeier, Bryan T. Hennessy, Zachary A. Knight, Marina Henneberg, Jianhua Hu, Antonina V. Kurtova, William G. Wierda, Michael J. Keating, Kevan M. Shokat, and Jan A. Burger Blood 2009 113: 5549-5557. Prepublished online March 24, 2009; DOI 10.1182/blood-2008-06-165068 [Abstract] [Full Text] [PDF] [Supplemental Tables]   TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia Jianhua Yu, Maxim Ershler, Li Yu, Min Wei, Björn Hackanson, Akihiko Yokohama, Takeki Mitsui, Chunhui Liu, Hsiaoyin Mao, Shujun Liu, Zhongfa Liu, Rossana Trotta, Chang-gong Liu, Xiuping Liu, Kun Huang, Jan Visser, Guido Marcucci, Christoph Plass, Alexander V. Belyavsky, and Michael A. Caligiuri Blood 2009 113: 5558-5567. Prepublished online March 27, 2009; DOI 10.1182/blood-2009-02-205732 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells Asish K. Ghosh, Tait D. Shanafelt, Amelia Cimmino, Cristian Taccioli, Stefano Volinia, Chang-gong Liu, George A. Calin, Carlo M. Croce, Denise A. Chan, Amato J. Giaccia, Charla Secreto, Linda E. Wellik, Yean K. Lee, Debabrata Mukhopadhyay, and Neil E. Kay Blood 2009 113: 5568-5574. Prepublished online March 31, 2009; DOI 10.1182/blood-2008-10-185686 [Abstract] [Full Text] [PDF]   MYELOID NEOPLASIA: Genome-wide association study to identify novel loci associated with therapy-related myeloid leukemia susceptibility Jeffrey A. Knight, Andrew D. Skol, Abhijit Shinde, Darcie Hastings, Richard A. Walgren, Jin Shao, Thelma R. Tennant, Mekhala Banerjee, James M. Allan, Michelle M. Le Beau, Richard A. Larson, Timothy A. Graubert, Nancy J. Cox, and Kenan Onel Blood 2009 113: 5575-5582. Prepublished online March 18, 2009; DOI 10.1182/blood-2008-10-183244 [Abstract] [Full Text] [PDF] [Supplemental Table]   Brief report  High frequency of RUNX1 biallelic alteration in acute myeloid leukemia secondary to familial platelet disorder Claude Preudhomme, Aline Renneville, Violaine Bourdon, Nathalie Philippe, Catherine Roche-Lestienne, Nicolas Boissel, Nathalie Dhedin, Jean-Marie André, Pascale Cornillet-Lefebvre, André Baruchel, Marie-Joelle Mozziconacci, and Hagay Sobol Blood 2009 113: 5583-5587. Prepublished online April 8, 2009; DOI 10.1182/blood-2008-07-168260 [Abstract] [Full Text] [PDF] [Supplemental Table and Figure]   PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS: Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung Malgorzata Wygrecka, Leigh M. Marsh, Rory E. Morty, Ingrid Henneke, Andreas Guenther, Juergen Lohmeyer, Philipp Markart, and Klaus T. Preissner Blood 2009 113: 5588-5598. Prepublished online January 30, 2009; DOI 10.1182/blood-2008-08-170837 [Abstract] [Full Text] [PDF] [Supplemental Figures]   PLATELETS AND THROMBOPOIESIS: Mutational inhibition of c-Myb or p300 ameliorates treatment-induced thrombocytopenia Douglas J. Hilton, Benjamin T. Kile, and Warren S. Alexander Blood 2009 113: 5599-5604. Prepublished online February 27, 2009; DOI 10.1182/blood-2008-12-195255 [Abstract] [Full Text] [PDF]   RED CELLS, IRON, AND ERYTHROPOIESIS: Brief report  Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron deficiency anemia Laura Silvestri, Flavia Guillem, Alessia Pagani, Antonella Nai, Claire Oudin, Muriel Silva, Fabienne Toutain, Caroline Kannengiesser, Carole Beaumont, Clara Camaschella, and Bernard Grandchamp Blood 2009 113: 5605-5608. Prepublished online April 8, 2009; DOI 10.1182/blood-2008-12-195594 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   THROMBOSIS AND HEMOSTASIS: Essential role of the disintegrin-like domain in ADAMTS13 function Rens de Groot, Ajoy Bardhan, Nalisha Ramroop, David A. Lane, and James T. B. Crawley Blood 2009 113: 5609-5616. Prepublished online February 20, 2009; DOI 10.1182/blood-2008-11-187914 [Abstract] [Full Text] [PDF]   JAK2V617F mutation for the early diagnosis of Ph– myeloproliferative neoplasms in patients with venous thromboembolism: a meta-analysis Francesco Dentali, Alessandro Squizzato, Lorenza Brivio, Lorena Appio, Leonardo Campiotti, Mark Crowther, Anna Maria Grandi, and Walter Ageno Blood 2009 113: 5617-5623. Prepublished online March 9, 2009; DOI 10.1182/blood-2008-12-196014 [Abstract] [Full Text] [PDF]   TRANSFUSION MEDICINE: Brief report  Regulatory T-cell status in red cell alloimmunized responder and nonresponder mice Weili Bao, Jin Yu, Susanne Heck, and Karina Yazdanbakhsh Blood 2009 113: 5624-5627. Prepublished online March 31, 2009; DOI 10.1182/blood-2008-12-193748 [Abstract] [Full Text] [PDF] [Supplemental Figures]   TRANSPLANTATION: Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity Claudio G. Brunstein, John E. Wagner, Daniel J. Weisdorf, Sarah Cooley, Harriet Noreen, Juliet N. Barker, Todd DeFor, Michael R. Verneris, Bruce R. Blazar, and Jeffrey S. Miller Blood 2009 113: 5628-5634. Prepublished online March 27, 2009; DOI 10.1182/blood-2008-12-197467 [Abstract] [Full Text] [PDF] [Supplemental Tables]   Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants Shannon J. Opiela, Tulay Koru-Sengul, and Becky Adkins Blood 2009 113: 5635-5643. Prepublished online January 23, 2009; DOI 10.1182/blood-2008-08-173658 [Abstract] [Full Text] [PDF]   Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation Kate A. Markey, Tatjana Banovic, Rachel D. Kuns, Stuart D. Olver, Alistair L. J. Don, Neil C. Raffelt, Yana A. Wilson, Liza J. Raggatt, Allison R. Pettit, Jonathan S. Bromberg, Geoffrey R. Hill, and Kelli P. A. MacDonald Blood 2009 113: 5644-5649. Prepublished online March 31, 2009; DOI 10.1182/blood-2008-12-191833 [Abstract] [Full Text] [PDF]   VASCULAR BIOLOGY: Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution Raghu P. Kataru, Keehoon Jung, Cholsoon Jang, Hanseul Yang, Reto A. Schwendener, Jung Eun Baik, Seung Hyun Han, Kari Alitalo, and Gou Young Koh Blood 2009 113: 5650-5659. Prepublished online April 3, 2009; DOI 10.1182/blood-2008-09-176776 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures][Additional Supplemental Figures]   Induction of CCL20 production by Kaposi sarcoma–associated herpesvirus: role of viral FLICE inhibitory protein K13-induced NF-B activation Vasu Punj, Hittu Matta, Sandra Schamus, Tianbing Yang, Yuan Chang, and Preet M. Chaudhary Blood 2009 113: 5660-5668. Prepublished online March 26, 2009; DOI 10.1182/blood-2008-10-186403 [Abstract] [Full Text] [PDF]   HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells Carmen Urbich, Lothar Rössig, David Kaluza, Michael Potente, Jes-Niels Boeckel, Andrea Knau, Florian Diehl, Jian-Guo Geng, Wolf-Karsten Hofmann, Andreas M. Zeiher, and Stefanie Dimmeler Blood 2009 113: 5669-5679. Prepublished online April 7, 2009; DOI 10.1182/blood-2009-01-196485 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries Inga Sörensen, Ralf H. Adams, and Achim Gossler Blood 2009 113: 5680-5688. Prepublished online January 14, 2009; DOI 10.1182/blood-2008-08-174508 [Abstract] [Full Text] [PDF] [Supplemental Figures]   CORRESPONDENCE: Selective engraftment of donor CD4+25high FOXP3-positive T cells in IPEX syndrome after nonmyeloablative hematopoietic stem cell transplantation Markus G. Seidel, Gerhard Fritsch, Thomas Lion, Birgit Jürgens, Andreas Heitger, Rosa Bacchetta, Anita Lawitschka, Christina Peters, Helmut Gadner, and Susanne Matthes-Martin Blood 2009 113: 5689-5691. [Full Text] [PDF]   Genetic variants in XRRC5 may predict development of venous thrombotic events in myeloma patients on thalidomide Prerna Tewari, Elaine Kenny, Anthony Staines, Stephen Chanock, Paul Browne, and Mark Lawler Blood 2009 113: 5691-5692. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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