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Receive this page by email each issue: [Sign up for eTOCs] Other Issues:   October 1 2009; 114 (14)   [Index by Author]  [Cover Caption] [Complete Inside Blood PDF]         INSIDE BLOOD        BLOOD WORK        REVIEW ARTICLES        CLINICAL TRIALS AND OBSERVATIONS        GENE THERAPY        HEMATOPOIESIS AND STEM CELLS        IMMUNOBIOLOGY        LYMPHOID NEOPLASIA        MYELOID NEOPLASIA        PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS        PLATELETS AND THROMBOPOIESIS        RED CELLS, IRON, AND ERYTHROPOIESIS        THROMBOSIS AND HEMOSTASIS        TRANSPLANTATION        VASCULAR BIOLOGY        ERRATA Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: Same mutation, different allele Karl J. Aichberger, Angela G. Fleischman, and Michael W. Deininger Blood 2009 114: 2853-2854. [Full Text] [PDF]   High coagulant factors & venous thrombosis Carine J. M. Doggen Blood 2009 114: 2854-2855. [Full Text] [PDF]   The hidden (and lazy) TCR Chiara Bonini and Vincenzo Russo Blood 2009 114: 2855-2856. [Full Text] [PDF]   Lyn and PKC order SHIP1 embargo Ulhas P. Naik Blood 2009 114: 2856-2857. [Full Text] [PDF]   Screens, iron, and leukemia Richard M. Stone and Daniel J. DeAngelo Blood 2009 114: 2857-2858. [Full Text] [PDF]   T cells helping GVHD: take-away lessons Daniel Fowler Blood 2009 114: 2858-2859. [Full Text] [PDF]   BLOOD WORK: Howell-Jolly body–like inclusions in neutrophils Blood 2009 114: 2860. [Full Text] [PDF]   REVIEW ARTICLES: Vascular complications after splenectomy for hematologic disorders Shelley E. Crary and George R. Buchanan Blood 2009 114: 2861-2868. Prepublished online July 27, 2009; DOI 10.1182/blood-2009-04-210112 [Abstract] [Full Text] [PDF]   CLINICAL TRIALS AND OBSERVATIONS: AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance Hendrik J. M. de Jonge, Eveline S. J. M. de Bont, Peter J. M. Valk, Jan Jacob Schuringa, Marcel Kies, Carolien M. Woolthuis, Ruud Delwel, Nic J. G. M. Veeger, Edo Vellenga, Bob Löwenberg, and Gerwin Huls Blood 2009 114: 2869-2877. Prepublished online August 10, 2009; DOI 10.1182/blood-2009-03-212688 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Coagulation factors IX through XIII and the risk of future venous thrombosis: the Longitudinal Investigation of Thromboembolism Etiology Mary Cushman, Ellen S. O'Meara, Aaron R. Folsom, and Susan R. Heckbert Blood 2009 114: 2878-2883. Prepublished online July 17, 2009; DOI 10.1182/blood-2009-05-219915 [Abstract] [Full Text] [PDF] [Supplemental Table]   Brief report  Donor-recipient mismatches in MHC class I chain-related gene A in unrelated donor transplantation lead to increased incidence of acute graft-versus-host disease Simrit Parmar, Marcos del Lima, Yizhou Zou, Poliana A. Patah, Ping Liu, Pedro Cano, Gabriela Rondon, Susana Pesoa, Leandro de Padua Silva, Muzaffar H. Qazilbash, Chitra Hosing, Uday Popat, Partow Kebriaei, Elizabeth J. Shpall, Sergio Giralt, Richard E. Champlin, Peter Stastny, and Marcelo Fernandez-Vina Blood 2009 114: 2884-2887. Prepublished online August 4, 2009; DOI 10.1182/blood-2009-05-223172 [Abstract] [Full Text] [PDF] [Supplemental Table]   GENE THERAPY: Lack of specific -retroviral vector long terminal repeat promoter silencing in patients receiving genetically engineered lymphocytes and activation upon lymphocyte restimulation William R. Burns, Zhili Zheng, Steven A. Rosenberg, and Richard A. Morgan Blood 2009 114: 2888-2899. Prepublished online July 9, 2009; DOI 10.1182/blood-2009-01-199216 [Abstract] [Full Text] [PDF]   HEMATOPOIESIS AND STEM CELLS: Wiskott-Aldrich syndrome protein is an effector of Kit signaling Maheswaran Mani, Shivkumar Venkatasubrahmanyam, Mrinmoy Sanyal, Shoshana Levy, Atul Butte, Kenneth Weinberg, and Thomas Jahn Blood 2009 114: 2900-2908. Prepublished online July 30, 2009; DOI 10.1182/blood-2009-01-200733 [Abstract] [Full Text] [PDF] [Supplemental Appendix, Table, and Figures]   IMMUNOBIOLOGY: Rho GTPase Cdc42 is essential for B-lymphocyte development and activation Fukun Guo, Chinavenmeni S. Velu, H. Leighton Grimes, and Yi Zheng Blood 2009 114: 2909-2916. Prepublished online August 11, 2009; DOI 10.1182/blood-2009-04-214676 [Abstract] [Full Text] [PDF]   The level of monocyte turnover predicts disease progression in the macaque model of AIDS Atsuhiko Hasegawa, Huining Liu, Binhua Ling, Juan T. Borda, Xavier Alvarez, Chie Sugimoto, Heather Vinet-Oliphant, Woong-Ki Kim, Kenneth C. Williams, Ruy M. Ribeiro, Andrew A. Lackner, Ronald S. Veazey, and Marcelo J. Kuroda Blood 2009 114: 2917-2925. Prepublished online April 21, 2009; DOI 10.1182/blood-2009-02-204263 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   LYMPHOID NEOPLASIA: Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2 Mamta Gupta, Stephen M. Ansell, Anne J. Novak, Shaji Kumar, Scott H. Kaufmann, and Thomas E. Witzig Blood 2009 114: 2926-2935. Prepublished online July 29, 2009; DOI 10.1182/blood-2009-05-220889 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells Ryan A. Wilcox, David A. Wada, Steven C. Ziesmer, Sherine F. Elsawa, Nneka I. Comfere, Allan B. Dietz, Anne J. Novak, Thomas E. Witzig, Andrew L. Feldman, Mark R. Pittelkow, and Stephen M. Ansell Blood 2009 114: 2936-2944. Prepublished online August 11, 2009; DOI 10.1182/blood-2009-05-220111 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma Alfons Navarro, Tania Diaz, Antonio Martinez, Anna Gaya, Aina Pons, Bernat Gel, Carles Codony, Gerardo Ferrer, Carmen Martinez, Emili Montserrat, and Mariano Monzo Blood 2009 114: 2945-2951. Prepublished online August 7, 2009; DOI 10.1182/blood-2009-02-204842 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility Ke Zhang, Daniel Kagan, Wendy DuBois, Richard Robinson, Valery Bliskovsky, William C. Vass, Shuling Zhang, and Beverly A. Mock Blood 2009 114: 2952-2960. Prepublished online August 4, 2009; DOI 10.1182/blood-2009-01-198812 [Abstract] [Full Text] [PDF] [Supplemental Methods, Table, and Figures]   Inhibition of the SDF-1–CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice Akira Kawaguchi, Yasuko Orba, Takashi Kimura, Hidekatsu Iha, Masao Ogata, Takahiro Tsuji, Akira Ainai, Tetsutaro Sata, Takashi Okamoto, William W. Hall, Hirofumi Sawa, and Hideki Hasegawa Blood 2009 114: 2961-2968. Prepublished online August 5, 2009; DOI 10.1182/blood-2008-11-189308 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Molecular profiling of CD3–CD4+ T cells from patients with the lymphocytic variant of hypereosinophilic syndrome reveals targeting of growth control pathways Marie Ravoet, Catherine Sibille, Chunyan Gu, Myriam Libin, Benjamin Haibe-Kains, Christos Sotiriou, Michel Goldman, Florence Roufosse, and Karen Willard-Gallo Blood 2009 114: 2969-2983. Prepublished online July 16, 2009; DOI 10.1182/blood-2008-08-175091 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figure]   MYELOID NEOPLASIA: AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML) Patrick P. Zarrinkar, Ruwanthi N. Gunawardane, Merryl D. Cramer, Michael F. Gardner, Daniel Brigham, Barbara Belli, Mazen W. Karaman, Keith W. Pratz, Gabriel Pallares, Qi Chao, Kelly G. Sprankle, Hitesh K. Patel, Mark Levis, Robert C. Armstrong, Joyce James, and Shripad S. Bhagwat Blood 2009 114: 2984-2992. Prepublished online August 4, 2009; DOI 10.1182/blood-2009-05-222034 [Abstract] [Full Text] [PDF] [Supplemental Table]   High Id1 expression is associated with poor prognosis in 237 patients with acute myeloid leukemia Ruoping Tang, Pierre Hirsch, Fanny Fava, Simona Lapusan, Christophe Marzac, Irène Teyssandier, Julia Pardo, Jean-Pierre Marie, and Ollivier Legrand Blood 2009 114: 2993-3000. Prepublished online July 30, 2009; DOI 10.1182/blood-2009-05-223115 [Abstract] [Full Text] [PDF]   Gene expression profiling of minimally differentiated acute myeloid leukemia: M0 is a distinct entity subdivided by RUNX1 mutation status Fernando P. G. Silva, Sigrid M. A. Swagemakers, Claudia Erpelinck-Verschueren, Bas J. Wouters, Ruud Delwel, Harry Vrieling, Peter van der Spek, Peter J. M. Valk, and Micheline Giphart-Gassler Blood 2009 114: 3001-3007. Prepublished online August 7, 2009; DOI 10.1182/blood-2009-03-211334 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Role of leukemia cell invadosome in extramedullary infiltration Michael Stefanidakis, Katja Karjalainen, Diana E. Jaalouk, Carl G. Gahmberg, Susan O'Brien, Renata Pasqualini, Wadih Arap, and Erkki Koivunen Blood 2009 114: 3008-3017. Prepublished online July 27, 2009; DOI 10.1182/blood-2008-04-148643 [Abstract] [Full Text] [PDF]   In essential thrombocythemia, multiple JAK2-V617F clones are present in most mutant-positive patients: a new disease paradigm Jonathan R. Lambert, Tamara Everington, David C. Linch, and Rosemary E. Gale Blood 2009 114: 3018-3023. Prepublished online June 18, 2009; DOI 10.1182/blood-2009-03-209916 [Abstract] [Full Text] [PDF] [Supplemental Methods and Table]   AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features Claudia Haferlach, Cristina Mecucci, Susanne Schnittger, Alexander Kohlmann, Marco Mancini, Antonio Cuneo, Nicoletta Testoni, Giovanna Rege-Cambrin, Antonella Santucci, Marco Vignetti, Paola Fazi, Maria Paola Martelli, Torsten Haferlach, and Brunangelo Falini Blood 2009 114: 3024-3032. Prepublished online May 8, 2009; DOI 10.1182/blood-2009-01-197871 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS: Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines Kazutaka Hayashida, William C. Parks, and Pyong Woo Park Blood 2009 114: 3033-3043. Prepublished online July 28, 2009; DOI 10.1182/blood-2009-02-204966 [Abstract] [Full Text] [PDF]   Neutrophil elastase is severely down-regulated in severe congenital neutropenia independent of ELA2 or HAX1 mutations but dependent on LEF-1 Julia Skokowa, John Paul Fobiwe, Lan Dan, Basant Kumar Thakur, and Karl Welte Blood 2009 114: 3044-3051. Prepublished online July 20, 2009; DOI 10.1182/blood-2008-11-188755 [Abstract] [Full Text] [PDF]   Brief report  Neutrophils express CD52 and exhibit complement-mediated lysis in the presence of alemtuzumab Lyn R. Ambrose, Anne-Sophie Morel, and Anthony N. Warrens Blood 2009 114: 3052-3055. Prepublished online July 28, 2009; DOI 10.1182/blood-2009-02-203075 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   PLATELETS AND THROMBOPOIESIS: Lyn, PKC-, SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretion Ramya Chari, Soochong Kim, Swaminathan Murugappan, Archana Sanjay, James L. Daniel, and Satya P. Kunapuli Blood 2009 114: 3056-3063. Prepublished online July 8, 2009; DOI 10.1182/blood-2008-11-188516 [Abstract] [Full Text] [PDF]   RED CELLS, IRON, AND ERYTHROPOIESIS: Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells Yanina Eberhard, Sean P. McDermott, Xiaoming Wang, Marcela Gronda, Amudha Venugopal, Tabitha E. Wood, Rose Hurren, Alessandro Datti, Robert A. Batey, Jeffrey Wrana, William E. Antholine, John Dick, and Aaron D. Schimmer Blood 2009 114: 3064-3073. Prepublished online July 9, 2009; DOI 10.1182/blood-2009-03-209965 [Abstract] [Full Text] [PDF] [Supplemental Figures]   THROMBOSIS AND HEMOSTASIS: Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo Zurina Romay-Penabad, Maria Guadalupe Montiel-Manzano, Tuya Shilagard, Elizabeth Papalardo, Gracie Vargas, Arun B. Deora, Michael Wang, Andrew T. Jacovina, Ethel Garcia-Latorre, Elba Reyes-Maldonado, Katherine A. Hajjar, and Silvia S. Pierangeli Blood 2009 114: 3074-3083. Prepublished online July 23, 2009; DOI 10.1182/blood-2008-11-188698 [Abstract] [Full Text] [PDF]   Cell adhesion molecule 1: a novel risk factor for venous thrombosis Sandra J. Hasstedt, Irene D. Bezemer, Peter W. Callas, Carla Y. Vossen, Winifred Trotman, Robert P. Hebbel, Christine Demers, Frits R. Rosendaal, and Edwin G. Bovill Blood 2009 114: 3084-3091. Prepublished online July 30, 2009; DOI 10.1182/blood-2009-05-219485 [Abstract] [Full Text] [PDF]   Fucosylated chondroitin sulfate inhibits plasma thrombin generation via targeting of the factor IXa heparin-binding exosite Yang Buyue and John P. Sheehan Blood 2009 114: 3092-3100. Prepublished online May 4, 2009; DOI 10.1182/blood-2009-02-203661 [Abstract] [Full Text] [PDF]   TRANSPLANTATION: Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease Tangsheng Yi, Ying Chen, Lin Wang, Gong Du, Daniel Huang, Dongchang Zhao, Heather Johnston, James Young, Ivan Todorov, Dale T. Umetsu, Lieping Chen, Yoichiro Iwakura, Fouad Kandeel, Stephen Forman, and Defu Zeng Blood 2009 114: 3101-3112. Prepublished online July 14, 2009; DOI 10.1182/blood-2009-05-219402 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Brief report  Impact of macrophage infiltration of skin lesions on survival after allogeneic stem cell transplantation: a clue to refractory graft-versus-host disease Satoshi Nishiwaki, Seitaro Terakura, Masafumi Ito, Tatsunori Goto, Aika Seto, Keisuke Watanabe, Mayumi Yanagisawa, Nobuhiko Imahashi, Shokichi Tsukamoto, Makoto Shimba, Yukiyasu Ozawa, and Koichi Miyamura Blood 2009 114: 3113-3116. Prepublished online July 30, 2009; DOI 10.1182/blood-2009-03-209635 [Abstract] [Full Text] [PDF]   VASCULAR BIOLOGY: Interleukin-33 induces angiogenesis and vascular permeability through ST2/TRAF6-mediated endothelial nitric oxide production Yeon-Sook Choi, Hyun-Jung Choi, Jeong-Ki Min, Bo-Jeong Pyun, Yong-Sun Maeng, Hongryeol Park, Jihye Kim, Young-Myeong Kim, and Young-Guen Kwon Blood 2009 114: 3117-3126. Prepublished online August 6, 2009; DOI 10.1182/blood-2009-02-203372 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Brief report  Endothelial colony-forming cells from patients with chronic myeloproliferative disorders lack the disease-specific molecular clonality marker Giovanna Piaggio, Vittorio Rosti, Mirko Corselli, Francesca Bertolotti, Gaetano Bergamaschi, Sarah Pozzi, Davide Imperiale, Barbara Chiavarina, Elisa Bonetti, Francesca Novara, Mario Sessarego, Laura Villani, Anna Garuti, Margherita Massa, Riccardo Ghio, Rita Campanelli, Andrea Bacigalupo, Alessandro Pecci, Gianluca Viarengo, Orsetta Zuffardi, Francesco Frassoni, and Giovanni Barosi Blood 2009 114: 3127-3130. Prepublished online July 23, 2009; DOI 10.1182/blood-2008-12-190991 [Abstract] [Full Text] [PDF]   ERRATA: Yang et al. SALL4 is a key regulator of survival and apoptosis in human leukemic cells. Blood. 2008;112(3):805–813. Blood 2009 114: 3131. [Full Text] [PDF]   Changelian et al. The specificity of JAK3 kinase inhibitors. Blood. 2008;111(4):2155–2157. Blood 2009 114: 3132. [Full Text] [PDF]   Hryniewicz et al. CTLA-4 blockade decreases TGF-beta, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques. Blood. 2006;108(12):3834–3842. Blood 2009 114: 3132. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

	Copyright © 2009 by American Society of Hematology         Online ISSN: 1528-0020