SEARCH:   Advanced

Receive this page by email each issue: [Sign up for eTOCs] Other Issues:   November 12 2009; 114 (20)   [Index by Author]  [Cover Caption] [Complete Inside Blood PDF]         INSIDE BLOOD        REVIEW ARTICLES        HOW I TREAT        CLINICAL TRIALS AND OBSERVATIONS        GENE THERAPY        HEMATOPOIESIS AND STEM CELLS        IMMUNOBIOLOGY        LYMPHOID NEOPLASIA        MYELOID NEOPLASIA        PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS        PLATELETS AND THROMBOPOIESIS        RED CELLS, IRON, AND ERYTHROPOIESIS        THROMBOSIS AND HEMOSTASIS        TRANSPLANTATION        VASCULAR BIOLOGY        CORRESPONDENCE        ERRATA Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: Platelet CFH: in search of the source Jan Willem N. Akkerman Blood 2009 114: 4323-4324. [Full Text] [PDF]   Hunting for the Achilles' heel of CLL John C. Byrd Blood 2009 114: 4324. [Full Text] [PDF]   Mining ferritin iron: 2 pathways Elizabeth C. Theil Blood 2009 114: 4325-4326. [Full Text] [PDF]   REVIEW ARTICLES: Acute graft-versus-host disease: from the bench to the bedside Gerard Socié and Bruce R. Blazar Blood 2009 114: 4327-4336. Prepublished online August 27, 2009; DOI 10.1182/blood-2009-06-204669 [Abstract] [Full Text] [PDF]   HOW I TREAT: How I treat mycosis fungoides and Sézary syndrome H. Miles Prince, Sean Whittaker, and Richard T. Hoppe Blood 2009 114: 4337-4353. Prepublished online August 20, 2009; DOI 10.1182/blood-2009-07-202895 [Abstract] [Full Text] [PDF]   CLINICAL TRIALS AND OBSERVATIONS: Evaluation of pentostatin in corticosteroid-refractory chronic graft-versus-host disease in children: a Pediatric Blood and Marrow Transplant Consortium study David A. Jacobsohn, Andrew L. Gilman, Alfred Rademaker, Brittan Browning, Michael Grimley, Leslie Lehmann, Eneida R. Nemecek, Kimberly Thormann, Kirk R. Schultz, and Georgia B. Vogelsang Blood 2009 114: 4354-4360. Prepublished online September 10, 2009; DOI 10.1182/blood-2009-05-224840 [Abstract] [Full Text] [PDF] [Supplemental Table]   The use of nilotinib or dasatinib after failure to 2 prior tyrosine kinase inhibitors: long-term follow-up Ravin J. Garg, Hagop Kantarjian, Susan O'Brien, Alfonso Quintás-Cardama, Stefan Faderl, Zeev Estrov, and Jorge Cortes Blood 2009 114: 4361-4368. Prepublished online September 3, 2009; DOI 10.1182/blood-2009-05-221531 [Abstract] [Full Text] [PDF]   Brief report  The persistence of immunophenotypically normal residual bone marrow plasma cells at diagnosis identifies a good prognostic subgroup of symptomatic multiple myeloma patients Bruno Paiva, Maria-Belén Vidriales, Gema Mateo, Jose J. Pérez, Maria Angeles Montalbán, Anna Sureda, Laura Montejano, Norma C. Gutiérrez, Alfonso García de Coca, Natalia de las Heras, Maria Victoria Mateos, Maria Consuelo López-Berges, Raimundo García-Boyero, Josefina Galende, Jose Hernández, Luis Palomera, Dolores Carrera, Rafael Martínez, Javier de la Rubia, Alejandro Martín, Yolanda González, Joan Bladé, Juan José Lahuerta, Alberto Orfao, Jesús F. San-Miguel, and on behalf of the GEM (Grupo Español de MM)/PETHEMA (Programa para el Estudio de la Terapéutica en Hemopatías Malignas) Cooperative Study Groups Blood 2009 114: 4369-4372. Prepublished online September 15, 2009; DOI 10.1182/blood-2009-05-221689 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   GENE THERAPY: Anti-CD3 antibodies modulate anti–factor VIII immune responses in hemophilia A mice after factor VIII plasmid-mediated gene therapy Baowei Peng, Peiqing Ye, David J. Rawlings, Hans D. Ochs, and Carol H. Miao Blood 2009 114: 4373-4382. Prepublished online September 21, 2009; DOI 10.1182/blood-2009-05-217315 [Abstract] [Full Text] [PDF]   HEMATOPOIESIS AND STEM CELLS: Necdin restricts proliferation of hematopoietic stem cells during hematopoietic regeneration Yasushi Kubota, Masatake Osawa, Lars Martin Jakt, Kazuaki Yoshikawa, and Shin-Ichi Nishikawa Blood 2009 114: 4383-4392. Prepublished online September 21, 2009; DOI 10.1182/blood-2009-07-230292 [Abstract] [Full Text] [PDF]   BMP4 regulates the hematopoietic stem cell niche Devorah C. Goldman, Alexis S. Bailey, Dana L. Pfaffle, Azzah Al Masri, Jan L. Christian, and William H. Fleming Blood 2009 114: 4393-4401. Prepublished online September 16, 2009; DOI 10.1182/blood-2009-02-206433 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Defects in osteoblast function but no changes in long-term repopulating potential of hematopoietic stem cells in a mouse chronic inflammatory arthritis model Yunglin D. Ma, Changwon Park, Haibo Zhao, Kwadwo A. Oduro, Jr, Xiaolin Tu, Fanxin Long, Paul M. Allen, Steven L. Teitelbaum, and Kyunghee Choi Blood 2009 114: 4402-4410. Prepublished online September 16, 2009; DOI 10.1182/blood-2008-12-196311 [Abstract] [Full Text] [PDF] [Supplemental Methods, Table, and Figures]   IMMUNOBIOLOGY: Homeostasis of dendritic cells in lymphoid organs is controlled by regulation of their precursors via a feedback loop Kristin Hochweller, Tewfik Miloud, Jörg Striegler, Shalin Naik, Günter J. Hämmerling, and Natalio Garbi Blood 2009 114: 4411-4421. Prepublished online September 18, 2009; DOI 10.1182/blood-2008-11-188045 [Abstract] [Full Text] [PDF]   CD56+ human blood dendritic cells effectively promote TH1-type T-cell responses Georg Gruenbacher, Hubert Gander, Andrea Rahm, Walter Nussbaumer, Nikolaus Romani, and Martin Thurnher Blood 2009 114: 4422-4431. Prepublished online September 17, 2009; DOI 10.1182/blood-2009-06-227256 [Abstract] [Full Text] [PDF]   The thymus-independent immunity conferred by a pneumococcal polysaccharide is mediated by long-lived plasma cells Morgan Taillardet, Ghina Haffar, Paul Mondière, Marie-Jeanne Asensio, Hanane Gheit, Nicolas Burdin, Thierry Defrance, and Laurent Genestier Blood 2009 114: 4432-4440. Prepublished online September 18, 2009; DOI 10.1182/blood-2009-01-200014 [Abstract] [Full Text] [PDF]   LYMPHOID NEOPLASIA: Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance Antonina V. Kurtova, Kumudha Balakrishnan, Rong Chen, Wei Ding, Susanne Schnabl, Maite P. Quiroga, Mariela Sivina, William G. Wierda, Zeev Estrov, Michael J. Keating, Medhat Shehata, Ulrich Jäger, Varsha Gandhi, Neil E. Kay, William Plunkett, and Jan A. Burger Blood 2009 114: 4441-4450. Prepublished online September 17, 2009; DOI 10.1182/blood-2009-07-233718 [Abstract] [Full Text] [PDF]   Stage-specific Arf tumor suppression in Notch1-induced T-cell acute lymphoblastic leukemia Emmanuel J. Volanakis, Richard T. Williams, and Charles J. Sherr Blood 2009 114: 4451-4459. Prepublished online September 16, 2009; DOI 10.1182/blood-2009-07-233346 [Abstract] [Full Text] [PDF]   Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen Lesley-Ann Sutton, Efterpi Kostareli, Anastasia Hadzidimitriou, Nikos Darzentas, Athanasios Tsaftaris, Achilles Anagnostopoulos, Richard Rosenquist, and Kostas Stamatopoulos Blood 2009 114: 4460-4468. Prepublished online August 27, 2009; DOI 10.1182/blood-2009-05-221309 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Chronic lymphocytic leukemia of Eµ-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression Thomas Enzler, Arnon P. Kater, Weizhou Zhang, George F. Widhopf, II, Han-Yu Chuang, Jason Lee, Esther Avery, Carlo M. Croce, Michael Karin, and Thomas J. Kipps Blood 2009 114: 4469-4476. Prepublished online September 15, 2009; DOI 10.1182/blood-2009-06-230169 [Abstract] [Full Text] [PDF]   Generation of CD8+ T cell–mediated immunity against idiotype-negative lymphoma escapees Bindu Varghese, Adam Widman, James Do, Behnaz Taidi, Debra K. Czerwinski, John Timmerman, Shoshana Levy, and Ronald Levy Blood 2009 114: 4477-4485. Prepublished online September 17, 2009; DOI 10.1182/blood-2009-05-223263 [Abstract] [Full Text] [PDF]   Gene expression–based classification and regulatory networks of pediatric acute lymphoblastic leukemia Zhigang Li, Wei Zhang, Minyuan Wu, Shanshan Zhu, Chao Gao, Lin Sun, Ruidong Zhang, Nan Qiao, Huiling Xue, Yamei Hu, Shilai Bao, Huyong Zheng, and Jing-Dong J. Han Blood 2009 114: 4486-4493. Prepublished online September 15, 2009; DOI 10.1182/blood-2009-04-218123 [Abstract] [Full Text] [PDF] [Supplemental Methods and Tables][Additional Supplemental Tables and Supplemental Figure]   A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display Sivasubramanian Baskar, Jessica M. Suschak, Ivan Samija, Ramaprasad Srinivasan, Richard W. Childs, Steven Z. Pavletic, Michael R. Bishop, and Christoph Rader Blood 2009 114: 4494-4502. Prepublished online August 10, 2009; DOI 10.1182/blood-2009-05-222786 [Abstract] [Full Text] [PDF]   Brief report  Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities Anja Mottok, Christoph Renné, Marc Seifert, Elsie Oppermann, Wolf Bechstein, Martin-Leo Hansmann, Ralf Küppers, and Andreas Bräuninger Blood 2009 114: 4503-4506. Prepublished online September 4, 2009; DOI 10.1182/blood-2009-06-225839 [Abstract] [Full Text] [PDF]   MYELOID NEOPLASIA: The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathways Mohamed Rahmani, Anh Anderson, Joseph Reza Habibi, Timothy Ryan Crabtree, Mandy Mayo, Hisashi Harada, Andrea Ferreira-Gonzalez, Paul Dent, and Steven Grant Blood 2009 114: 4507-4516. Prepublished online September 22, 2009; DOI 10.1182/blood-2008-09-177881 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS: GM-CSF and IL-4 induce dendritic cell differentiation and disrupt osteoclastogenesis through M-CSF receptor shedding by up-regulation of TNF- converting enzyme (TACE) Masahiro Hiasa, Masahiro Abe, Ayako Nakano, Asuka Oda, Hiroe Amou, Shinsuke Kido, Kyoko Takeuchi, Kumiko Kagawa, Kenichiro Yata, Toshihiro Hashimoto, Shuji Ozaki, Kenzo Asaoka, Eiji Tanaka, Keiji Moriyama, and Toshio Matsumoto Blood 2009 114: 4517-4526. Prepublished online September 17, 2009; DOI 10.1182/blood-2009-04-215020 [Abstract] [Full Text] [PDF] [Supplemental Figures]   The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signaling Kathleen Szczur, Yi Zheng, and Marie-Dominique Filippi Blood 2009 114: 4527-4537. Prepublished online September 14, 2009; DOI 10.1182/blood-2008-12-195164 [Abstract] [Full Text] [PDF]   PLATELETS AND THROMBOPOIESIS: Platelet-associated complement factor H in healthy persons and patients with atypical HUS Christoph Licht, Fred G. Pluthero, Ling Li, Hilary Christensen, Sandra Habbig, Bernd Hoppe, Denis F. Geary, Peter F. Zipfel, and Walter H. A. Kahr Blood 2009 114: 4538-4545. Prepublished online August 24, 2009; DOI 10.1182/blood-2009-03-205096 [Abstract] [Full Text] [PDF]   RED CELLS, IRON, AND ERYTHROPOIESIS: Specific iron chelators determine the route of ferritin degradation Ivana De Domenico, Diane McVey Ward, and Jerry Kaplan Blood 2009 114: 4546-4551. Prepublished online August 11, 2009; DOI 10.1182/blood-2009-05-224188 [Abstract] [Full Text] [PDF] [Supplemental Figure]   THROMBOSIS AND HEMOSTASIS: The therapeutic effect of bone marrow–derived liver cells in the phenotypic correction of murine hemophilia A Neelam Yadav, Sumod Kanjirakkuzhiyil, Suresh Kumar, Manish Jain, Ashutosh Halder, Renu Saxena, and Asok Mukhopadhyay Blood 2009 114: 4552-4561. Prepublished online September 14, 2009; DOI 10.1182/blood-2009-02-202788 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Brief report  Recombinant canine B-domain–deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model Denise E. Sabatino, Christian Furlan Freguia, Raffaella Toso, Andrey Santos, Elizabeth P. Merricks, Haig H. Kazazian, Jr, Timothy C. Nichols, Rodney M. Camire, and Valder R. Arruda Blood 2009 114: 4562-4565. Prepublished online September 21, 2009; DOI 10.1182/blood-2009-05-220327 [Abstract] [Full Text] [PDF]   TRANSPLANTATION: Bone marrow as an alternative site for islet transplantation Elisa Cantarelli, Raffaella Melzi, Alessia Mercalli, Valeria Sordi, Giuliana Ferrari, Carsten Werner Lederer, Emanuela Mrak, Alessandro Rubinacci, Maurilio Ponzoni, Giovanni Sitia, Luca G. Guidotti, Ezio Bonifacio, and Lorenzo Piemonti Blood 2009 114: 4566-4574. Prepublished online September 22, 2009; DOI 10.1182/blood-2009-03-209973 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Superagonistic CD28 stimulation of allogeneic T cells protects from acute graft-versus-host disease Niklas Beyersdorf, Xin Ding, Thomas Hünig, and Thomas Kerkau Blood 2009 114: 4575-4582. Prepublished online August 31, 2009; DOI 10.1182/blood-2009-04-218248 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figure]   VASCULAR BIOLOGY: Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes Heinz Läubli, Katharina-Susanne Spanaus, and Lubor Borsig Blood 2009 114: 4583-4591. Prepublished online September 24, 2009; DOI 10.1182/blood-2008-10-186585 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures][Additional Supplemental Figures]   A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis Robert C. Doebele, Frank T. Schulze-Hoepfner, Jia Hong, Alexandre Chlenski, Benjamin D. Zeitlin, Kushboo Goel, Suzana Gomes, Yuru Liu, Mark K. Abe, Jacques E. Nor, Mark W. Lingen, and Marsha Rich Rosner Blood 2009 114: 4592-4600. Prepublished online August 26, 2009; DOI 10.1182/blood-2009-04-217042 [Abstract] [Full Text] [PDF]   CORRESPONDENCE: The role of cytogenetic abnormalities in acute myeloid leukemia with NPM1 mutations and no FLT3 internal tandem duplication Jean Baptiste Micol, Nicolas Boissel, Aline Renneville, Sylvie Castaigne, Claude Gardin, Claude Preudhomme, and Hervé Dombret Blood 2009 114: 4601-4602. [Full Text] [PDF]   Response: NPM1-mutated AML is an entity irrespective of whether or not chromosomal aberrations are present Claudia Haferlach, Marco Vignetti, Torsten Haferlach, and Brunangelo Falini Blood 2009 114: 4602-4603. [Full Text] [PDF]   Elevated fibrinogen ' ratio is associated with cardiovascular diseases and acute phase reaction but not with clinical outcome Elim Y. L. Cheung, Hans L. Vos, Marieke J. H. A. Kruip, Heleen M. den Hertog, J. Wouter Jukema, and Moniek P. M. de Maat Blood 2009 114: 4603-4604. [Full Text] [PDF]   Response: Elevated fibrinogen ' ratios and clinical outcomes Ulrike Nowak-Göttl, Hartmut Weiler, and Monika Stoll Blood 2009 114: 4604-4605. [Full Text] [PDF]   Allogeneic transplantation for children and adolescents with Hodgkin lymphoma Norbert Schmitz, Anna Sureda, Giorgio Dini, Alexander Claviez, and on behalf of the Lymphoma and Pediatric Diseases Working Parties Blood 2009 114: 4605-4606. [Full Text] [PDF]   ERRATA: van de Vosse et al. Antisense-mediated exon skipping to correct IL-12Rβ1 deficiency in T cells. Blood. 2009;113(19):4548–4555. Blood 2009 114: 4607. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

	Copyright © 2009 by American Society of Hematology         Online ISSN: 1528-0020