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Receive this page by email each issue: [Sign up for eTOCs] Other Issues:   August 20 2009; 114 (8)   [Index by Author]  [Cover Caption] [Complete Inside Blood PDF]         INSIDE BLOOD        REVIEW ARTICLES        HOW I TREAT        CLINICAL TRIALS AND OBSERVATIONS        HEMATOPOIESIS AND STEM CELLS        IMMUNOBIOLOGY        LYMPHOID NEOPLASIA        MYELOID NEOPLASIA        PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS        PLATELETS AND THROMBOPOIESIS        THROMBOSIS AND HEMOSTASIS        TRANSFUSION MEDICINE        TRANSPLANTATION        VASCULAR BIOLOGY        CORRESPONDENCE        ERRATUM Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: Stem cells unscramble yolk sac hematopoiesis Paul Gadue and Mitchell J. Weiss Blood 2009 114: 1455-1456. [Abstract] [Full Text] [PDF]   Finishing off fibrils Morie Gertz Blood 2009 114: 1456-1457. [Abstract] [Full Text] [PDF]   Blocking PD-1 in cancer immunotherapy Gianpietro Dotti Blood 2009 114: 1457-1458. [Abstract] [Full Text] [PDF]   Taking aim at protein translation in AML Martin Carroll Blood 2009 114: 1458-1459. [Abstract] [Full Text] [PDF]   A case of mistaken identity Sergio Querol Blood 2009 114: 1459-1460. [Abstract] [Full Text] [PDF]   REVIEW ARTICLES: Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells Thierry VandenDriessche, Zoltán Ivics, Zsuzsanna Izsvák, and Marinee K. L. Chuah Blood 2009 114: 1461-1468. Prepublished online May 26, 2009; DOI 10.1182/blood-2009-04-210427 [Abstract] [Full Text] [PDF]   HOW I TREAT: How I treat mantle cell lymphoma Michele Ghielmini and Emanuele Zucca Blood 2009 114: 1469-1476. Prepublished online June 25, 2009; DOI 10.1182/blood-2009-02-179739 [Abstract] [Full Text] [PDF]   CLINICAL TRIALS AND OBSERVATIONS: Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele Paola Guglielmelli, Giovanni Barosi, Giorgina Specchia, Alessandro Rambaldi, Francesco Lo Coco, Elisabetta Antonioli, Lisa Pieri, Alessandro Pancrazzi, Vanessa Ponziani, Federica Delaini, Giovanni Longo, Emanuele Ammatuna, Vincenzo Liso, Alberto Bosi, Tiziano Barbui, and Alessandro M. Vannucchi Blood 2009 114: 1477-1483. Prepublished online June 23, 2009; DOI 10.1182/blood-2009-04-216044 [Abstract] [Full Text] [PDF]   Risk of arterial cardiovascular events in patients after pulmonary embolism Frederikus A. Klok, Inge C.M. Mos, Lisette Broek, Jouke T. Tamsma, Frits R. Rosendaal, Albert de Roos, and Menno V. Huisman Blood 2009 114: 1484-1488. Prepublished online June 23, 2009; DOI 10.1182/blood-2009-05-220491 [Abstract] [Full Text] [PDF]   Weekly and twice-weekly bortezomib in patients with systemic AL amyloidosis: results of a phase 1 dose-escalation study Donna E. Reece, Vaishali Sanchorawala, Ute Hegenbart, Giampaolo Merlini, Giovanni Palladini, Jean-Paul Fermand, Robert A. Vescio, Xiangyang Liu, Yusri A. Elsayed, Andrew Cakana, Raymond L. Comenzo, and for the VELCADE CAN2007 Study Group Blood 2009 114: 1489-1497. Prepublished online June 4, 2009; DOI 10.1182/blood-2009-02-203398 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   HEMATOPOIESIS AND STEM CELLS: Repression of BMI1 in normal and leukemic human CD34+ cells impairs self-renewal and induces apoptosis Aleksandra Rizo, Sandra Olthof, Lina Han, Edo Vellenga, Gerald de Haan, and Jan Jacob Schuringa Blood 2009 114: 1498-1505. Prepublished online June 25, 2009; DOI 10.1182/blood-2009-03-209734 [Abstract] [Full Text] [PDF]   A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell–derived primitive hematopoiesis Olena Klimchenko, Marcella Mori, Antonio DiStefano, Thierry Langlois, Frédéric Larbret, Yann Lecluse, Olivier Feraud, William Vainchenker, Françoise Norol, and Najet Debili Blood 2009 114: 1506-1517. Prepublished online May 28, 2009; DOI 10.1182/blood-2008-09-178863 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   IMMUNOBIOLOGY: Spatiotemporal regulation of intracellular trafficking of Toll-like receptor 9 by an inhibitory receptor, Ly49Q Mariko Yoshizaki, Aya Tazawa, Eiji Kasumi, Shigemi Sasawatari, Kenji Itoh, Taeko Dohi, Takehiko Sasazuki, Kayo Inaba, Andrew P. Makrigiannis, and Noriko Toyama-Sorimachi Blood 2009 114: 1518-1527. Prepublished online June 15, 2009; DOI 10.1182/blood-2008-12-192344 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Programmed death 1 signaling on chronic myeloid leukemia–specific T cells results in T-cell exhaustion and disease progression Sabine Mumprecht, Christian Schürch, Juerg Schwaller, Max Solenthaler, and Adrian F. Ochsenbein Blood 2009 114: 1528-1536. Prepublished online May 6, 2009; DOI 10.1182/blood-2008-09-179697 [Abstract] [Full Text] [PDF]   Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired Mojgan Ahmadzadeh, Laura A. Johnson, Bianca Heemskerk, John R. Wunderlich, Mark E. Dudley, Donald E. White, and Steven A. Rosenberg Blood 2009 114: 1537-1544. Prepublished online May 7, 2009; DOI 10.1182/blood-2008-12-195792 [Abstract] [Full Text] [PDF]   PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model Long Zhang, Thomas F. Gajewski, and Justin Kline Blood 2009 114: 1545-1552. Prepublished online May 5, 2009; DOI 10.1182/blood-2009-03-206672 [Abstract] [Full Text] [PDF]   Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response Christof Geldmacher, Ian S. Metzler, Sodsai Tovanabutra, Tedi E. Asher, Emma Gostick, David R. Ambrozak, Constantinos Petrovas, Alexandra Schuetz, Njabulo Ngwenyama, Gustavo Kijak, Leonard Maboko, Michael Hoelscher, Francine McCutchan, David A. Price, Daniel C. Douek, and Richard A. Koup Blood 2009 114: 1553-1562. Prepublished online June 19, 2009; DOI 10.1182/blood-2009-02-206193 [Abstract] [Full Text] [PDF] [Supplemental Figures]   LYMPHOID NEOPLASIA: Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM Roberto Alonso, Mónica López-Guerra, Ramanda Upshaw, Shanta Bantia, Caroline Smal, Françoise Bontemps, Chantal Manz, Thomas Mehrling, Neus Villamor, Elias Campo, Emili Montserrat, and Dolors Colomer Blood 2009 114: 1563-1575. Prepublished online June 18, 2009; DOI 10.1182/blood-2009-02-207654 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198–fibroblast growth factor receptor-1 chimeric tyrosine kinase Mingqiang Ren, Xiurong Li, and John K. Cowell Blood 2009 114: 1576-1584. Prepublished online June 8, 2009; DOI 10.1182/blood-2009-03-212704 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figure]   The proteomic signature of NPM/ALK reveals deregulation of multiple cellular pathways Megan S. Lim, Mary L. Carlson, David K. Crockett, G. Chris Fillmore, David R. Abbott, Olaotan F. Elenitoba-Johnson, Sheryl R. Tripp, George Z. Rassidakis, L. Jeffrey Medeiros, Philippe Szankasi, and Kojo S. J. Elenitoba-Johnson Blood 2009 114: 1585-1595. Prepublished online June 16, 2009; DOI 10.1182/blood-2009-02-204735 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   MYELOID NEOPLASIA: Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyperproliferation and restores myeloid differentiation Ayten Kandilci and Gerard C. Grosveld Blood 2009 114: 1596-1606. Prepublished online June 26, 2009; DOI 10.1182/blood-2009-02-205443 [Abstract] [Full Text] [PDF]   KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation Yukimasa Shiotsu, Hitoshi Kiyoi, Yuichi Ishikawa, Ryohei Tanizaki, Makiko Shimizu, Hiroshi Umehara, Kenichi Ishii, Yumiko Mori, Kazutaka Ozeki, Yosuke Minami, Akihiro Abe, Hiroshi Maeda, Tadakazu Akiyama, Yutaka Kanda, Yuko Sato, Shiro Akinaga, and Tomoki Naoe Blood 2009 114: 1607-1617. Prepublished online June 18, 2009; DOI 10.1182/blood-2009-01-199307 [Abstract] [Full Text] [PDF]   Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia Jerome Tamburini, Alexa S. Green, Valerie Bardet, Nicolas Chapuis, Sophie Park, Lise Willems, Madalina Uzunov, Norbert Ifrah, François Dreyfus, Catherine Lacombe, Patrick Mayeux, and Didier Bouscary Blood 2009 114: 1618-1627. Prepublished online May 20, 2009; DOI 10.1182/blood-2008-10-184515 [Abstract] [Full Text] [PDF] [Supplemental Appendix and Figures]   Brief report  Analysis of the Ten-Eleven Translocation 2 (TET2) gene in familial myeloproliferative neoplasms Cécile Saint-Martin, Gwendoline Leroy, François Delhommeau, Gérard Panelatti, Sabrina Dupont, Chloé James, Isabelle Plo, Dominique Bordessoule, Christine Chomienne, André Delannoy, Alain Devidas, Martine Gardembas-Pain, Françoise Isnard, Yves Plumelle, Olivier Bernard, William Vainchenker, Albert Najman, Christine Bellanné-Chantelot, and the French Group of Familial Myeloproliferative Disorders Blood 2009 114: 1628-1632. Prepublished online June 29, 2009; DOI 10.1182/blood-2009-01-197525 [Abstract] [Full Text] [PDF] [Supplemental Appendix and Tables]   PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS: Surface RANKL of Toll-like receptor 4–stimulated human neutrophils activates osteoclastic bone resorption Arpita Chakravarti, Marie-Astrid Raquil, Philippe Tessier, and Patrice E. Poubelle Blood 2009 114: 1633-1644. Prepublished online June 22, 2009; DOI 10.1182/blood-2008-09-178301 [Abstract] [Full Text] [PDF]   PLATELETS AND THROMBOPOIESIS: Role of sialic acid for platelet life span: exposure of β-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor–expressing liver macrophages and hepatocytes Anne Louise Sørensen, Viktoria Rumjantseva, Sara Nayeb-Hashemi, Henrik Clausen, John H. Hartwig, Hans H. Wandall, and Karin M. Hoffmeister Blood 2009 114: 1645-1654. Prepublished online June 11, 2009; DOI 10.1182/blood-2009-01-199414 [Abstract] [Full Text] [PDF]   Brief report  Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation Claudio Graziano, Simona Carone, Emanuele Panza, Flora Marino, Pamela Magini, Giovanni Romeo, Andrea Pession, and Marco Seri Blood 2009 114: 1655-1657. Prepublished online June 24, 2009; DOI 10.1182/blood-2009-04-217851 [Abstract] [Full Text] [PDF] [Supplemental Table]   THROMBOSIS AND HEMOSTASIS: Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation Fionnuala Ni Ainle, Roger J. S. Preston, P. Vincent Jenkins, Hendrik J. Nel, Jennifer A. Johnson, Owen P. Smith, Barry White, Padraic G. Fallon, and James S. O'Donnell Blood 2009 114: 1658-1665. Prepublished online June 16, 2009; DOI 10.1182/blood-2009-05-222109 [Abstract] [Full Text] [PDF]   Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site Thomas J. Raife, Wenjing Cao, Bonnie S. Atkinson, Bruce Bedell, Robert R. Montgomery, Steven R. Lentz, George F. Johnson, and X. Long Zheng Blood 2009 114: 1666-1674. Prepublished online June 18, 2009; DOI 10.1182/blood-2009-01-195461 [Abstract] [Full Text] [PDF]   Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies Surya V. Seshan, Claus-Werner Franzke, Patricia Redecha, Marc Monestier, Nigel Mackman, and Guillermina Girardi Blood 2009 114: 1675-1683. Prepublished online June 17, 2009; DOI 10.1182/blood-2009-01-199117 [Abstract] [Full Text] [PDF]   TRANSFUSION MEDICINE: Mislabeled units of umbilical cord blood detected by a quality assurance program at the transplantation center Jeffrey McCullough, David McKenna, Diane Kadidlo, David Maurer, Harriett J. Noreen, Kathy French, Claudio Brunstein, and John E. Wagner Blood 2009 114: 1684-1688. Prepublished online June 1, 2009; DOI 10.1182/blood-2009-02-205047 [Abstract] [Full Text] [PDF]   TRANSPLANTATION: Impact of HLA disparity in the graft-versus-host direction on engraftment in adult patients receiving reduced-intensity cord blood transplantation Naofumi Matsuno, Atsushi Wake, Naoyuki Uchida, Kazuya Ishiwata, Hideki Araoka, Shinsuke Takagi, Masanori Tsuji, Hisashi Yamamoto, Daisuke Kato, Yoshiko Matsuhashi, Sachiko Seo, Kazuhiro Masuoka, Shigesaburo Miyakoshi, Shigeyoshi Makino, Akiko Yoneyama, Yoshinobu Kanda, and Shuichi Taniguchi Blood 2009 114: 1689-1695. Prepublished online June 17, 2009; DOI 10.1182/blood-2008-12-194696 [Abstract] [Full Text] [PDF]   VASCULAR BIOLOGY: Direct crosstalk between mast cell–TNF and TNFR1-expressing endothelia mediates local tissue inflammation Manfred Kneilling, Reinhard Mailhammer, Lothar Hültner, Tanja Schönberger, Kerstin Fuchs, Martin Schaller, Daniel Bukala, Steffen Massberg, Christian A. Sander, Heidi Braumüller, Martin Eichner, Konrad L. Maier, Rupert Hallmann, Bernd J. Pichler, Roland Haubner, Meinrad Gawaz, Klaus Pfeffer, Tilo Biedermann, and Martin Röcken Blood 2009 114: 1696-1706. Prepublished online June 22, 2009; DOI 10.1182/blood-2008-11-187682 [Abstract] [Full Text] [PDF] [Supplemental Methods, Figures, and Videos]   EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures Ombretta Salvucci, Dragan Maric, Matina Economopoulou, Shuhei Sakakibara, Simone Merlin, Antonia Follenzi, and Giovanna Tosato Blood 2009 114: 1707-1716. Prepublished online May 1, 2009; DOI 10.1182/blood-2008-12-192294 [Abstract] [Full Text] [PDF] [Supplemental Figures and Videos]   CORRESPONDENCE: Sensitivity of serum free light chain measurement of residual disease in multiple myeloma patients Graham Peter Mead and Mark Trehane Drayson Blood 2009 114: 1717. [Full Text] [PDF]   A novel G6PC3 homozygous 1-bp deletion as a cause of severe congenital neutropenia Juan I. Aróstegui, José Sánchez de Toledo, Mariona Pascal, Carlos García, Jordi Yagüe, and Cristina Díaz de Heredia Blood 2009 114: 1718-1719. [Full Text] [PDF]   ERRATUM: Harir et al. Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade. Blood. 2008;112(6):2463-2473. Blood 2009 114: 1720. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

	Copyright © 2009 by American Society of Hematology         Online ISSN: 1528-0020