Cover figure courtesy of Frenette et al, "Platelet-Endothelial Interactions in Inflamed Mesenteric Venules." Fluorescence intravital microscopy of a mesenteric venule depicting two rolling platelets (upper right; comet-like) and one sticking platelet (left; bright dot). The high fluorescence intensity confers platelets their apparent large size. The visible contours of the venules result from fluorescence of free-flowing platelets. Direction of blood flow is left to right.