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November 5, 2009; 114 (19)
PLENARY PAPER
- M. Heuser, L. M. Sly, B. Argiropoulos, F. Kuchenbauer, C. Lai, A. Weng, M. Leung, G. Lin, C. Brookes, S. Fung, P. J. Valk, R. Delwel, B. Lowenberg, G. Krystal, and R. K. Humphries
- Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal
REVIEW ARTICLE
- S. Uitte de Willige, K. F. Standeven, H. Philippou, and R. A. S. Ariens
- The pleiotropic role of the fibrinogen
  chain in hemostasis
HOW I TREAT
- H. E. Heslop
- How I treat EBV lymphoproliferation
CLINICAL TRIALS AND OBSERVATIONS
- D. Chirnomas, A. L. Smith, J. Braunstein, Y. Finkelstein, L. Pereira, A. K. Bergmann, F. D. Grant, C. Paley, M. Shannon, and E. J. Neufeld
- Deferasirox pharmacokinetics in patients with adequate versus inadequate response
- W. Cozen, A. S. Hamilton, P. Zhao, M. T. Salam, D. M. Deapen, B. N. Nathwani, L. M. Weiss, and T. M. Mack
- A protective role for early oral exposures in the etiology of young adult Hodgkin lymphoma
- L. J. Noetzli, J. Papudesi, T. D. Coates, and J. C. Wood
- Pancreatic iron loading predicts cardiac iron loading in thalassemia major
- F. Giles, N. Vey, D. DeAngelo, K. Seiter, W. Stock, R. Stuart, D. Boskovic, A. Pigneux, M. Tallman, J. Brandwein, J. Kell, T. Robak, P. Staib, X. Thomas, A. Cahill, M. Albitar, and S. O'Brien
- Phase 3 randomized, placebo-controlled, double-blind study of high-dose continuous infusion cytarabine alone or with laromustine (VNP40101M) in patients with acute myeloid leukemia in first relapse
GENE THERAPY
- C. H. Miao, B. R. Harmeling, S. F. Ziegler, B. C. Yen, T. Torgerson, L. Chen, R. J. Yau, B. Peng, A. R. Thompson, H. D. Ochs, and D. J. Rawlings
- CD4+FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice
HEMATOPOIESIS AND STEM CELLS
- M. L. Chen, T. D. Logan, M. L. Hochberg, S. G. Shelat, X. Yu, G. E. Wilding, W. Tan, G. C. Kujoth, T. A. Prolla, M. A. Selak, M. Kundu, M. Carroll, and J. E. Thompson
- Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction
- B. Frisch, R. Porter, B. J. Gigliotti, A. J. Olm-Shipman, J. M. Weber, R. J. O'Keefe, C. T. Jordan, and L. M. Calvi
- In vivo prostaglandin E2 treatment alters the bone marrow microenvironment and preferentially expands short-term hematopoietic stem cells
- S. Rodriguez, A. Chora, B. Goumnerov, C. Mumaw, S. Goebel, L. Fernandez, H. Baydoun, H. HogenEsch, D. M. Dombkowski, C. A. Karlewicz, S. Rice, L. G. Rahme, and N. Carlesso
- Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis
- V. A. Bourke, C. J. Watchman, J. D. Reith, M. L. Jorgensen, A. Dieudonne, and W. E. Bolch
- Brief report. Spatial gradients of blood vessels and hematopoietic stem and progenitor cells within the marrow cavities of the human skeleton
IMMUNOBIOLOGY
- T. Zhang, S. Liu, P. Yang, C. Han, J. Wang, J. Liu, Y. Han, Y. Yu, and X. Cao
- Fibronectin maintains survival of mouse natural killer (NK) cells via CD11b/Src/
 -catenin pathway
- S. Borte, Q. Pan-Hammarstrom, C. Liu, U. Sack, M. Borte, U. Wagner, D. Graf, and L. Hammarstrom
- Interleukin-21 restores immunoglobulin production ex vivo in patients with common variable immunodeficiency and selective IgA deficiency
- H. Robins, P. Campregher, S. Srivastava, A. Wacher, C. J. Turtle, O. Kahsai, S. R. Riddell, E. H. Warren, and C. S. Carlson
- Comprehensive assessment of T-cell receptor -chain diversity in
 T cells
- E. Marcenaro, C. Cantoni, S. Pesce, C. Prato, D. Pende, S. Agaugue, L. Moretta, and A. Moretta
- Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction
- S. M. Wood, M. Meeths, S. C. C. Chiang, A. G. Bechensteen, J. J. Boelens, C. Heilmann, H. Horiuchi, S. Rosthoj, O. Rutynowska, J. Winiarski, J. L. Stow, M. Nordenskjold, J.-I. Henter, H.-G. Ljunggren, and Y. T. Bryceson
- Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity
- A. K. L. Cheung, D. J. Gottlieb, B. Plachter, S. Pepperl-Klindworth, S. Avdic, A. L. Cunningham, A. Abendroth, and B. Slobedman
- The role of the human cytomegalovirus UL111A gene in down-regulating CD4+ T-cell recognition of latently infected cells: implications for virus elimination during latency
- S. Di Nunzio, M. Cecconi, L. Passerini, A. N. McMurchy, U. Baron, I. Turbachova, S. Vignola, E. Valencic, A. Tommasini, A. Junker, G. Cazzola, S. Olek, M. K. Levings, L. Perroni, M. G. Roncarolo, and R. Bacchetta
- Brief report. Wild-type FOXP3 is selectively active in CD4+CD25hi regulatory T cells of healthy female carriers of different FOXP3 mutations
LYMPHOID NEOPLASIA
- H. Qin, S.-c. Cha, S. S. Neelapu, Y. Lou, J. Wei, and Y.-J. Liu, and L. W. Kwak
- Vaccine site inflammation potentiates idiotype DNA vaccine-induced therapeutic T-cell, and not B-cell, dependent antilymphoma immunity
- L. S. Chen, S. Redkar, D. Bearss, W. G. Wierda, and V. Gandhi
- Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia lymphocytes
- Z. Li, H. Wang, L. Xue, D.-M. Shin, D. Roopenian, W. Xu, C.-F. Qi, M. Y. Sangster, C. J. Orihuela, E. Tuomanen, J. E. Rehg, X. Cui, Q. Zhang, H. C. Morse III, and S. W. Morris
- E
 -BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF- B pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma
- A. Kotani, D. Ha, J. Hsieh, P. K. Rao, D. Schotte, M. L. den Boer, S. A. Armstrong, and H. F. Lodish
- miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221
- S. Sharma and A. Lichtenstein
- Aberrant splicing of the E-cadherin transcript is a novel mechanism of gene silencing in chronic lymphocytic leukemia cells
MYELOID NEOPLASIA
- F. Pellicano, M. Copland, H. G. Jorgensen, J. Mountford, B. Leber, and T. L. Holyoake
- BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38- cells, through activation of protein kinase C
- S. R. Bandi, C. Brandts, M. Rensinghoff, R. Grundler, L. Tickenbrock, G. Kohler, J. Duyster, W. E. Berdel, C. Muller-Tidow, H. Serve, and B. Sargin, on behalf of the Study Alliance Leukemias
- E3 ligase-defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
- J. Schymeinsky, R. Gerstl, I. Mannigel, K. Niedung, D. Frommhold, K. Panthel, J. Heesemann, M. Sixt, T. Quast, W. Kolanus, A. Mocsai, J. Wienands, M. Sperandio, and B. Walzog
- A fundamental role of mAbp1 in neutrophils: impact on 2 integrin-mediated phagocytosis and adhesion in vivo
PLATELETS AND THROMBOPOIESIS
- L. Gilles, D. Bluteau, S. Boukour, Y. Chang, Y. Zhang, T. Robert, P. Dessen, N. Debili, O. A. Bernard, W. Vainchenker, and H. Raslova
- MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9
RED CELLS, IRON, AND ERYTHROPOIESIS
- S.-C. Huang, A. Cho, S. Norton, E. S. Liu, J. Park, A. Zhou, I. D. Munagala, A. C. Ou, G. Yang, A. Wickrema, T. K. Tang, and E. J. Benz Jr
- Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5 exons of protein 4.1R gene
- A. K. Tripathi, W. Sha, V. Shulaev, M. F. Stins, and D. J. Sullivan Jr
- Plasmodium falciparum-infected erythrocytes induce NF-B-regulated inflammatory pathways in human cerebral endothelium
- D. Vernimmen, F. Marques-Kranc, J. A. Sharpe, J. A. Sloane-Stanley, W. G. Wood, H. A. C. Wallace, A. J. H. Smith, and D. R. Higgs
- Chromosome looping at the human -globin locus is mediated via the major upstream regulatory element (HS
 40)
THROMBOSIS AND HEMOSTASIS
- C. Abarrategui-Garrido, R. Martinez-Barricarte, M. Lopez-Trascasa, S. Rodriguez de Cordoba, and P. Sanchez-Corral
- Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome
- A. Undas, K. Zawilska, M. Ciesla-Dul, A. Lehmann-Kopydlowska, A. Skubiszak, K. Ciepluch, and W. Tracz
- Altered fibrin clot structure/function in patients with idiopathic venous thromboembolism and in their relatives
TRANSFUSION MEDICINE
- C. A. Tormey and G. Stack
- Brief report. Immunogenicity of blood group antigens: a mathematical model corrected for antibody evanescence with exclusion of naturally occurring and pregnancy-related antibodies
TRANSPLANTATION
- A. M. Leen, A. Christin, G. D. Myers, H. Liu, C. R. Cruz, P. J. Hanley, A. A. Kennedy-Nasser, K. S. Leung, A. P. Gee, R. A. Krance, M. K. Brenner, H. E. Heslop, C. M. Rooney, and C. M. Bollard
- Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation
- M. R. Verneris, C. G. Brunstein, J. Barker, M. L. MacMillan, T. DeFor, D. H. McKenna, M. J. Burke, B. R. Blazar, J. S. Miller, P. B. McGlave, D. J. Weisdorf, and J. E. Wagner
- Relapse risk after umbilical cord blood transplantation: enhanced graft-versus-leukemia effect in recipients of 2 units
VASCULAR BIOLOGY
- B. Zhang, U. M. Dietrich, J.-G. Geng, R. Bicknell, J. D. Esko, and L. Wang
- Repulsive axon guidance molecule Slit3 is a novel angiogenic factor
- G. Madlambayan, J. Butler, K. Hosaka, M. Jorgensen, D. Fu, S. M. Guthrie, A. K. Shenoy, A. Brank, K. J. Russell, J. Otero, D. W. Siemann, E. W. Scott, and C. R. Cogle
- Bone marrow stem and progenitor cell contribution to neovasculogenesis is dependent on model system with SDF-1 as a permissive trigger
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