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Blood's First Edition Papers: Last updated November 6, 2009 [View by section] To enable Blood's readers to learn about new scientific findings at the earliest possible moment, the Journal has decided to prepublish, in manuscript format, all accepted articles shortly after acceptance as "First Edition Papers." First Edition Papers have undergone full scientific review but none of the editorial preparation, such as copyediting, typesetting, and proofreading, which is mandatory for all articles published in the regular print and online issues of Blood. Disclaimer More about Blood's First Edition Papers: To see an article, click its [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. 6 November 2009 Pietro Sodani, Antonella Isgro, Javid Gaziev, Paola Polchi, Katia Paciaroni, Marco Marziali, Maria Domenica Simone, Andrea Roveda, Aldo Montuoro, Cecilia Alfieri, Gioia De Angelis, Cristiano Gallucci, Buket Erer, Giancarlo Isacchi, Francesco Zinno, Gaspare Adorno, Alessandro Lanti, Lawrence Faulkner, Manuela Testi, Marco Andreani, and Guido Lucarelli Purified T-depleted, CD34+ peripheral blood and bone marrow cell transplantation from haploidentical mother to child with thalassemia Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-05-218982 [Abstract] [Full Text] [PDF]   Meena Kanduri, Nicola Cahill, Hanna Goransson, Camilla Enstrom, Fergus Ryan, Anders Isaksson, and Richard Rosenquist Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-07-232868 [Abstract] [Full Text] [PDF]   Hiroshi Watarai, Andrei Rybouchkin, Naomi Hongo, Yuko Nagata, Sakura Sakata, Etsuko Sekine, Nyambayar Dashtsoodol, Takuya Tashiro, Shin-ichiro Fujii, Kanako Shimizu, Kenji Mori, Kyoko Masuda, Hiroshi Kawamoto, Haruhiko Koseki, and Masaru Taniguchi Generation of functional NKT cells in vitro from embryonic stem cells bearing rearranged invariant V14-J18 TCR gene Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-04-217729 [Abstract] [Full Text] [PDF]   Celine Cougoule, Veronique Le Cabec, Renaud Poincloux, Talal Al Saati, Jean-Louis Mege, Guillaume Tabouret, Clifford A. Lowell, Nathalie Laviolette-Malirat, and Isabelle Maridonneau-Parini Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-04-218735 [Abstract] [Full Text] [PDF]   Jianhua Yu, Hsiaoyin Charlene Mao, Min Wei, Tiffany Hughes, Jianying Zhang, Il-kyoo Park, Shujun Liu, Susan McClory, Guido Marcucci, Rossana Trotta, and Michael A. Caligiuri CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK cell subsets Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-04-215491 [Abstract] [Full Text] [PDF]   Donald M. Arnold, Ishac Nazi, Aurelio Santos, Howard Chan, Nancy M. Heddle, Theodore E. Warkentin, and John G. Kelton Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-06-222448 [Abstract] [Full Text] [PDF]   R. Beedholm-Ebsen, K. van de Wetering, T. Hardlei, E. Nexo, P. Borst, and S. K. Moestrup Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-07-232587 [Abstract] [Full Text] [PDF]   Nicholas M. Andronicos, Emily I. Chen, Nagyung Baik, Hongdong Bai, Caitlin M. Parmer, William B. Kiosses, Mark P. Kamps, John R. Yates III, Robert J. Parmer, and Lindsey A. Miles Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activation Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2008-11-188938 [Abstract] [Full Text] [PDF]   Daniel J. Bridges, James Bunn, Jan A. van Mourik, Georges Grau, Roger J.S. Preston, Malcolm Molyneux, Valery Combes, James S. O'Donnell, Bas de Laat, and Alister Craig Rapid activation of endothelial cells enables P. falciparum adhesion to platelet decorated von Willebrand factor strings Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-07-235150 [Abstract] [Full Text] [PDF]   Bing Z. Carter, Duncan H. Mak, Wendy D. Schober, Erich Koller, Clemencia Pinilla, Lyubomir T. Vassilev, John C. Reed, and Michael Andreeff Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-03-212563 [Abstract] [Full Text] [PDF]   Anthony V Moorman, Lucy Chilton, Jennifer Wilkinson, Hannah M Ensor, Nick Bown, and Stephen J Proctor A population based cytogenetic study of adults with acute lymphoblastic leukaemia (ALL) Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-07-232124 [Abstract] [Full Text] [PDF]   Tao Wu, Jiangguo Lin, Miguel A. Cruz, Jing-Fei Dong, and Cheng Zhu Force-induced cleavage of single VWF A1A2A3-tridomains by ADAMTS-13 Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-03-210369 [Abstract] [Full Text] [PDF]   Caryn Y. Ito, Daniel C. Kirouac, Gerard J. Madlambayan, Mei Yu, Ian Rogers, and Peter W. Zandstra The AC133+CD38-, but not the rhodamine-low phenotype, tracks LTC-IC and SRC function in human cord blood ex vivo expansion cultures Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-07-228106 [Abstract] [Full Text] [PDF]   Jinah Han, Young Jun Koh, Hye Rin Moon, Hyun Gee Ryoo, Chung-Hyun Cho, Injune Kim, and Gou Young Koh Adipose tissue is an extramedullary reservoir for functional hematopoietic stem and progenitor cells Blood First Edition Paper, prepublished online November 6, 2009; DOI 10.1182/blood-2009-05-219923 [Abstract] [Full Text] [PDF]   4 November 2009 Martin Pelletier, Laura Maggi, Alessandra Micheletti, Elena Lazzeri, Nicola Tamassia, Claudio Costantini, Lorenzo Cosmi, Claudio Lunardi, Francesco Annunziato, Sergio Romagnani, and Marco A. Cassatella Evidence for a cross-talk between human neutrophils and Th17 cells Blood First Edition Paper, prepublished online November 4, 2009; DOI 10.1182/blood-2009-04-216085 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Sujith Samarasinghe, Christoph Mancao, Martin Pule, Niga Nawroly, Helen Karlsson, Jennifer Brewin, Peter Openshaw, H. Bobby Gaspar, Paul Veys, and Persis J. Amrolia Functional characterization of alloreactive T-cells identifies CD25 and CD71 as optimal targets for a clinically applicable allodepletion strategy Blood First Edition Paper, prepublished online November 4, 2009; DOI 10.1182/blood-2009-08-235895 [Abstract] [Full Text] [PDF]   Jordan D Dimitrov, Suryasarathi Dasgupta, Ana-Maria Navarrete, Sandrine Delignat, Yohann Repesse, Yann Meslier, Cyril Planchais, Maud Teyssandier, Roberto Motterlini, Jagadeesh Bayry, Srinivas V Kaveri, and Sebastien Lacroix-Desmazes Induction of heme oxygenase-1 in factor VIII-deficient mice reduces the immune response to therapeutic factor VIII Blood First Edition Paper, prepublished online November 4, 2009; DOI 10.1182/blood-2009-04-216408 [Abstract] [Full Text] [PDF]   Kate Vandyke, Stephen Fitter, Andrea L. Dewar, Timothy P. Hughes, and Andrew C.W. Zannettino Dysregulation of bone remodelling by imatinib mesylate Blood First Edition Paper, prepublished online November 4, 2009; DOI 10.1182/blood-2009-08-237404 [Abstract] [Full Text] [PDF]   Nicola Bonadies, Thomas Pabst, and Beatrice U. Mueller Heterozygous deletion of the PU.1 locus in human AML Blood First Edition Paper, prepublished online November 4, 2009; DOI 10.1182/blood-2009-03-212225 [Abstract] [Full Text] [PDF]   Isao Kobayashi, Hiromasa Ono, Tadaaki Moritomo, Koichiro Kano, Teruyuki Nakanishi, and Toshio Suda Comparative gene expression analysis of zebrafish and mammals identifies common regulators in hematopoietic stem cells Blood First Edition Paper, prepublished online November 4, 2009; DOI 10.1182/blood-2009-07-232322 [Abstract] [Full Text] [PDF]   3 November 2009 Luis I Sanchez-Abarca, Silvia Gutierrez-Cosio, Carlos Santamaria, Teresa Caballero-Velazquez, Belen Blanco, Carmen Herrero-Sanchez, Juan L Garcia, Soraya Carrancio, Pilar Hernandez-Campo, Francisco J Gonzalez, Teresa Flores, Laura Ciudad, Esteban Ballestar, Consuelo del Canizo, Jesus F San Miguel, and Jose A Perez-Simon Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting Blood First Edition Paper, prepublished online November 3, 2009; DOI 10.1182/blood-2009-03-210393 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Alfredo Dragani, Silvia Pascale, Antonio Recchiuti, Domenico Mattoscio, Stefano Lattanzio, Giovanna Petrucci, Luciana Mucci, Elisabetta Ferrante, Aida Habib, Franco O. Ranelletti, Giovanni Ciabattoni, Giovanni Davi, Carlo Patrono, and Bianca Rocca The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy Blood First Edition Paper, prepublished online November 3, 2009; DOI 10.1182/blood-2009-08-236679 [Abstract] [Full Text] [PDF]   Frank C. Cackowski, Judith L. Anderson, Kenneth D. Patrene, Rushir J. Choksi, Steven D. Shapiro, Jolene J. Windle, Harry C. Blair, and G. David Roodman Osteoclasts are important for bone angiogenesis Blood First Edition Paper, prepublished online November 3, 2009; DOI 10.1182/blood-2009-08-237628 [Abstract] [Full Text] [PDF]   Holger Weishaupt, Mikael Sigvardsson, and Joanne L. Attema Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells Blood First Edition Paper, prepublished online November 3, 2009; DOI 10.1182/blood-2009-07-235176 [Abstract] [Full Text] [PDF]   Francesco Forconi, Kathleen N. Potter, Isla Wheatley, Nikos Darzentas, Elisa Sozzi, Kostas Stamatopoulos, C. Ian Mockridge, Graham Packham, and Freda K. Stevenson The normal IGHV1-69-derived B-cell repertoire contains "stereotypic" patterns characteristic of unmutated CLL Blood First Edition Paper, prepublished online November 3, 2009; DOI 10.1182/blood-2009-06-225813 [Abstract] [Full Text] [PDF]   2 November 2009 Murielle Roussel, Philippe Moreau, Anne Huynh, Jean-Yves Mary, Clotaire Danho, Denis Caillot, Cyrille Hulin, Christophe Fruchart, Gerald Marit, Brigitte Pegourie, Pascal Lenain, Carla Araujo, Brigitte Kolb, Edouard Randriamalala, Bruno Royer, Anne-Marie Stoppa, Mammoun Dib, Veronique Dorvaux, Laurent Garderet, Claire Mathiot, Herve Avet-Loiseau, Jean-Luc Harousseau, and Michel Attal Bortezomib and high dose melphalan as conditioning regimen before autologous stem cell transplantation in patients with de novo multiple myeloma: a phase II study of the Intergroupe Francophone du Myelome (IFM) Blood First Edition Paper, prepublished online November 2, 2009; DOI 10.1182/blood-2009-06-229658 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Ashley N Mays, Neil Osheroff, Yuanyuan Xiao, Joseph L Wiemels, Carolyn A Felix, Jo Ann W Byl, Kandeepan Saravanamuttu, Andrew Peniket, Robert Corser, Cherry Chang, Christine Hoyle, Anne N Parker, Syed K Hasan, Francesco Lo-Coco, Ellen Solomon, and David Grimwade Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia Blood First Edition Paper, prepublished online November 2, 2009; DOI 10.1182/blood-2009-07-235051 [Abstract] [Full Text] [PDF] [Supplemental Figure]   30 October 2009 Scott E. James, Nural N. Orgun, Thomas F. Tedder, Mark J. Shlomchik, Michael C. Jensen, Yukang Lin, Philip D. Greenberg, and Oliver W. Press Antibody mediated B cell depletion prior to adoptive immunotherapy with T cells expressing CD20-specific chimeric T cell receptors facilitates eradication of leukemia in immunocompetent mice Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-08-232967 [Abstract] [Full Text] [PDF]   Toshiko Tanaka, Cindy N. Roy, Wenliang Yao, Amy Matteini, Richard D. Semba, Dan Arking, Jeremy D. Walston, Linda P. Fried, Andrew Singleton, Jack Guralnik, Goncalo R. Abecasis, Stefania Bandinelli, Dan L. Longo, and Luigi Ferrucci A genome-wide association analysis of serum iron concentrations Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-07-232496 [Abstract] [Full Text] [PDF]   David Garcia, Edward Libby, and Mark A. Crowther The new oral anticoagulants Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-09-241851 [Abstract] [Full Text] [PDF]   Anna Kalota and Alan M. Gewirtz A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-06-227751 [Abstract] [Full Text] [PDF]   Audrey Varin, Subhankar Mukhopadhyay, Georges Herbein, and Siamon Gordon Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-08-236711 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Jun Yang, Xin Liu, Susan B. Nyland, Ranran Zhang, Lindsay K. Ryland, Kathleen Broeg, Kendall Thomas Baab, Nancy Ruth Jarbadan, Rosalyn Irby, and Thomas P. Loughran Jr. Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-06-223719 [Abstract] [Full Text] [PDF]   Helen E Heslop, Karen S Slobod, Martin A Pule, Gregory A Hale, Alexandra Rousseau, Colton A Smith, Catherine M Bollard, Hao Liu, Meng-Fen Wu, Richard J Rochester, Persis J Amrolia, Julia L Hurwitz, Malcolm K Brenner, and Cliona M Rooney Long term outcome of EBV specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-08-239186 [Abstract] [Full Text] [PDF]   Sebastian J. Saur, Veena Sangkhae, Amy E. Geddis, Kenneth Kaushansky, and Ian S. Hitchcock Ubiquitination and degradation of the thrombopoietin receptor c-Mpl Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-06-227033 [Abstract] [Full Text] [PDF]   H. Dohner, E. H. Estey, S. Amadori, F. R. Appelbaum, T. Buchner, A. K. Burnett, H. Dombret, P. Fenaux, D. Grimwade, R. A. Larson, F. Lo Coco, T. Naoe, D. Niederwieser, G. J. Ossenkoppele, M. A. Sanz, J. Sierra, M. S. Tallman, B. Lowenberg, and C. D. Bloomfield Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel,on behalf of the European LeukemiaNet Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-07-235358 [Abstract] [Full Text] [PDF]   Huining Kang, I-Ming Chen, Carla S. Wilson, Edward J. Bedrick, Richard C. Harvey, Susan R. Atlas, Meenakshi Devidas, Charles G. Mullighan, Xuefei Wang, Maurice Murphy, Kerem Ar, Walker Wharton, Michael J. Borowitz, W. Paul Bowman, Deepa Bhojwani, William L. Carroll, Bruce Matthew Camitta, Gregory H. Reaman, Malcolm A. Smith, James R. Downing, Stephen P. Hunger, and Cheryl L. Willman Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-05-218560 [Abstract] [Full Text] [PDF]   Esther Carreras, Sean Turner, Mark Barton Frank, Nicholas Knowlton, Jeanette Osban, Michael Centola, Chae Gyu Park, Amie Simmons, Jose Alberola-Ila, and Susan Kovats Estrogen receptor signaling promotes dendritic cell differentiation by increasing expression of the transcription factor IRF4 Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-08-236935 [Abstract] [Full Text] [PDF]   Keguo Li, Yannick Blum, Anjali Verma, Zhong Liu, Kallal Pramanik, Noah R. Leigh, Chang Z. Chun, Ganesh V. Samant, Baofeng Zhao, Maija K. Garnaas, Mark A. Horswill, Stephen A. Stanhope, Paula E. North, Robert Q. Miao, George A. Wilkinson, Markus Affolter, and Ramani Ramchandran A non-coding antisense RNA in tie-1 locus regulates tie-1 function in vivo Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-09-242180 [Abstract] [Full Text] [PDF]   H M Lokhorst, B van der Holt, S Zweegman, E Vellenga, S Croockewit, M H van Oers, P von dem Borne, P Wijermans, R Schaafsma, O de Weerdt, S Wittebol, Michel Delforge, H Berenschot, G M Bos, K S Jie, H Sinnege, M van Marwijk-Kooy, P Joosten, M C Minnema, R Ammerlaan, and P Sonneveld A randomized phase III study on the effect of thalidomide combined with Adriamycin, dexamethasone (TAD), and high-dose melphalan, followed by thalidomide maintenance in patients with multiple myeloma Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-05-222539 [Abstract] [Full Text] [PDF]   Susan Branford, Junia V Melo, and Timothy P. Hughes Selecting optimal second-line tyrosine kinase inhibitor therapy for chronic myeloid leukemia patients after imatinib failure - does the BCR-ABL mutation status really matter? Blood First Edition Paper, prepublished online October 30, 2009; DOI 10.1182/blood-2009-08-215939 [Abstract] [Full Text] [PDF]   28 October 2009 Nathalie Droin, Arnaud Jacquel, Jean-Baptiste Hendra, Cindy Racoeur, Caroline Truntzer, Delphine Pecqueur, Naima Benikhlef, Marion Ciudad, Leslie Guery, Valerie Jooste, Erick Dufour, Pierre Fenaux, Bruno Quesnel, Olivier Kosmider, Michaela Fontenay, Patrick Ducoroy, and Eric Solary Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia Blood First Edition Paper, prepublished online October 28, 2009; DOI 10.1182/blood-2009-05-224352 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Xiang Li, Shunji Jia, Shaohe Wang, Yuemeng Wang, and Anming Meng Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos Blood First Edition Paper, prepublished online October 28, 2009; DOI 10.1182/blood-2009-06-227777 [Abstract] [Full Text] [PDF]   Lina Jansson and Jonas Larsson W41/W41 blastocyst complementation: a system for genetic modeling of hematopoiesis Blood First Edition Paper, prepublished online October 28, 2009; DOI 10.1182/blood-2009-07-235622 [Abstract] [Full Text] [PDF]   Stephan Bluml, Gordin Zupkovitz, Stefanie Kirchberger, Maria Seyerl, Valery N. Bochkov, Karl Stuhlmeier, Otto Majdic, Gerhard J. Zlabinger, Christian Seiser, and Johannes Stockl Epigenetic regulation of dendritic cell differentiation and function by oxidized phospholipids Blood First Edition Paper, prepublished online October 28, 2009; DOI 10.1182/blood-2008-11-191429 [Abstract] [Full Text] [PDF]   27 October 2009 C. L. Fisher, N. Pineault, C. Brookes, C. D. Helgason, H. Ohta, C. Bodner, J. L. Hess, R. K. Humphries, and H. W. Brock Loss-of-function Additional sex combs-like1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia Blood First Edition Paper, prepublished online October 27, 2009; DOI 10.1182/blood-2009-07-230698 [Abstract] [Full Text] [PDF]   Aaron Yun Chen, Elizabeth Yan Zhang, Wuxiang Guan, Fang Cheng, Steve Kleiboeker, Thomas M. Yankee, and Jianming Qiu The small 11kDa non-structural protein of human parvovirus B19 plays a key role in inducing apoptosis during B19 virus infection of primary erythroid progenitor cells Blood First Edition Paper, prepublished online October 27, 2009; DOI 10.1182/blood-2009-04-215756 [Abstract] [Full Text] [PDF]   Connie Duckers, Paolo Simioni, Luca Spiezia, Claudia Radu, Paolo Dabrilli, Sabrina Gavasso, Jan Rosing, and Elisabetta Castoldi Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms Blood First Edition Paper, prepublished online October 27, 2009; DOI 10.1182/blood-2009-08-237719 [Abstract] [Full Text] [PDF]   Elina Kivi, Kati Elima, Kristiina Aalto, Yvonne Nymalm, Kaisa Auvinen, Erkki Koivunen, Diana M. Otto, Paul R. Crocker, Tiina A. Salminen, Marko Salmi, and Sirpa Jalkanen Human Siglec-10 can bind to vascular adhesion protein-1 (VAP-1) and generate enzymatic products Blood First Edition Paper, prepublished online October 27, 2009; DOI 10.1182/blood-2009-04-219253 [Abstract] [Full Text] [PDF]   A. Keith Stewart, Paul G. Richardson, and Jesus F. San-Miguel How I treat multiple myeloma in younger patients Blood First Edition Paper, prepublished online October 27, 2009; DOI 10.1182/blood-2009-07-204651 [Abstract] [Full Text] [PDF]   Fumio Nakahara, Mamiko Sakata-Yanagimoto, Yukiko Komeno, Naoko Kato, Tomoyuki Uchida, Kyoko Haraguchi, Keiki Kumano, Yuka Harada, Hironori Harada, Jiro Kitaura, Seishi Ogawa, Mineo Kurokawa, Toshio Kitamura, and Shigeru Chiba Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia Blood First Edition Paper, prepublished online October 27, 2009; DOI 10.1182/blood-2009-05-222836 [Abstract] [Full Text] [PDF]   Iain Moore, Lisa Strain, Isabel Pappworth, David Kavanagh, Paul N Barlow, Andew P Herbert, Christoph Q Schmidt, Scott J Staniforth, Lucy V Holmes, Roy Ward, Lynn Morgan, Tim H J Goodship, and Kevin J Marchbank Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4 and with mutations in CFH, CFI, CD46, and C3 in patients with atypical haemolytic uraemic syndrome Blood First Edition Paper, prepublished online October 27, 2009; DOI 10.1182/blood-2009-05-221549 [Abstract] [Full Text] [PDF]   26 October 2009 Patrycja Sroczynska, Christophe Lancrin, Valerie Kouskoff, and Georges Lacaud The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis Blood First Edition Paper, prepublished online October 26, 2009; DOI 10.1182/blood-2009-05-222307 [Abstract] [Full Text] [PDF]   23 October 2009 Dominique J.P.M. Stumpel, Pauline Schneider, Eddy H.J. van Roon, Judith M. Boer, Paola de Lorenzo, Maria G. Valsecchi, Renee X. de Menezes, Rob Pieters, and Ronald W. Stam Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options Blood First Edition Paper, prepublished online October 23, 2009; DOI 10.1182/blood-2009-06-227660 [Abstract] [Full Text] [PDF] [Supplemental Results, Methods, Tables, and Figures]   Kim L. Rice, Itsaso Hormaeche, Sergei Doulatov, Jared M. Flatow, David Grimwade, Ken I. Mills, Magdalena Leiva, Julien Ablain, Charuta Ambardekar, Melanie J. McConnell, John E. Dick, and Jonathan D. Licht Comprehensive genomic screens identify a role for PLZF-RAR as a positive regulator of cell proliferation via direct regulation of c-MYC Blood First Edition Paper, prepublished online October 23, 2009; DOI 10.1182/blood-2009-03-206524 [Abstract] [Full Text] [PDF]   Roberto M. Lemoli, Valentina Salvestrini, Elisa Bianchi, Francesco Bertolini, Miriam Fogli, Marilina Amabile, Agostino Tafuri, Simona Salati, Roberta Zini, Nicoletta Testoni, Cristina Rabascio, Lara Rossi, Ines Martin-Padura, Fausto Castagnetti, Paola Marighetti, Giovanni Martinelli, Michele Baccarani, Sergio Ferrari, and Rossella Manfredini Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD34- cell population with intrinsic resistance to imatinib Blood First Edition Paper, prepublished online October 23, 2009; DOI 10.1182/blood-2008-08-176016 [Abstract] [Full Text] [PDF]   Przemyslaw Juszczynski, Linfeng Chen, Evan O'Donnell, Jose M. Polo, Stella M. Ranuncolo, Riccardo Dalla-Favera, Ari Melnick, and Margaret A. Shipp BCL6 regulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt Blood First Edition Paper, prepublished online October 23, 2009; DOI 10.1182/blood-2009-02-204362 [Abstract] [Full Text] [PDF]   Cindy Banh, Celine Fugere, and Laurent Brossay Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling Blood First Edition Paper, prepublished online October 23, 2009; DOI 10.1182/blood-2009-06-228353 [Abstract] [Full Text] [PDF]   Yacine Boulaftali, Frederic Adam, Laurence Venisse, Veronique Ollivier, Benjamin Richard, Sabrina Taieb, Denis Monard, Remi Favier, Marie-Christine Alessi, Marijke Bryckaert, Veronique Arocas, Martine Jandrot-Perrus, and Marie-Christine Bouton Anticoagulant and antithrombotic properties of platelet protease nexin-1 Blood First Edition Paper, prepublished online October 23, 2009; DOI 10.1182/blood-2009-04-217240 [Abstract] [Full Text] [PDF]   Bob Meek, Silvie Cloosen, Chiara Borsotti, Catharina H.M.J. Van Elssen, Joris Vanderlocht, Melanie C.A. Schnijderberg, Marjolein W.M. van der Poel, Bas Leewis, Reinout Hesselink, Markus G. Manz, Yoshimoto Katsura, Hiroshi Kawamoto, Wilfred T.V. Germeraad, and Gerard M.J. Bos In vitro differentiated T/NK cell progenitors derived from human CD34+ cells mature in the thymus Blood First Edition Paper, prepublished online October 23, 2009; DOI 10.1182/blood-2009-05-223990 [Abstract] [Full Text] [PDF]   22 October 2009 Ye Ding, Yuka Harada, Jun Imagawa, Akiro Kimura, and Hironori Harada AML1/RUNX1 point mutation possibly promotes leukemic transformation in myeloproliferative neoplasms Blood First Edition Paper, prepublished online October 22, 2009; DOI 10.1182/blood-2009-06-223982 [Abstract] [Full Text] [PDF]   John G Gribben How I treat CLL upfront Blood First Edition Paper, prepublished online October 22, 2009; DOI 10.1182/blood-2009-08-207126 [Abstract] [Full Text] [PDF]   Karl J. Aichberger, Karoline V. Gleixner, Irina Mirkina, Sabine Cerny-Reiterer, Barbara Peter, Veronika Ferenc, Michael Kneidinger, Christian Baumgartner, Matthias Mayerhofer, Alexander Gruze, Winfried F. Pickl, Christian Sillaber, and Peter Valent Identification of pro-apoptotic Bim as a tumor suppressorin neoplastic mast cells: role of KIT D816V and effects of various targeted drugs Blood First Edition Paper, prepublished online October 22, 2009; DOI 10.1182/blood-2008-08-175190 [Abstract] [Full Text] [PDF]   Jitka Malcikova, Jana Smardova, Ludmila Rocnova, Boris Tichy, Petr Kuglik, Vladimira Vranova, Sona Cejkova, Miluse Svitakova, Hana Skuhrova Francova, Yvona Brychtova, Michael Doubek, Martin Brejcha, Martin Klabusay, Jiri Mayer, Sarka Pospisilova, and Martin Trbusek Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival and response to DNA damage Blood First Edition Paper, prepublished online October 22, 2009; DOI 10.1182/blood-2009-07-234708 [Abstract] [Full Text] [PDF] [Supplemental Table and Figure]   Ramiro Garzon, Catherine E.A. Heaphy, Violaine Havelange, Muller Fabbri, Stefano Volinia, Twee Tsao, Nicola Zanesi, Steven M. Kornblau, Guido Marcucci, George A. Calin, Michael Andreeff, and Carlo M. Croce MicroRNA 29b functions in acute myeloid leukemia Blood First Edition Paper, prepublished online October 22, 2009; DOI 10.1182/blood-2009-03-211938 [Abstract] [Full Text] [PDF]   Julie Lacombe, Sabine Herblot, Shanti Rojas-Sutterlin, Andre Haman, Stephane Barakat, Norman N. Iscove, Guy Sauvageau, and Trang Hoang Scl regulates the quiescence and the long-term competence of hematopoietic stem cells Blood First Edition Paper, prepublished online October 22, 2009; DOI 10.1182/blood-2009-01-201384 [Abstract] [Full Text] [PDF]   Scott M. Vanderwerf, Johanna Svahn, Susan Olson, R. Keaney Rathbun, Christina Harrington, Jane Yates, Winifred Keeble, David C. Anderson, Praveen Anur, Noemi F. Pereira, Daniela V. Pilonetto, Ricardo Pasquini, and Grover C. Bagby TLR8-dependent TNF over-expression in Fanconi anemia group C cells Blood First Edition Paper, prepublished online October 22, 2009; DOI 10.1182/blood-2009-05-222414 [Abstract] [Full Text] [PDF]   21 October 2009 Michel Jourdan, Anouk Caraux, John De Vos, Genevieve Fiol, Marion Larroque, Chantal Cognot, Caroline Bret, Christophe Duperray, Dirk Hose, and Bernard Klein An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization Blood First Edition Paper, prepublished online October 21, 2009; DOI 10.1182/blood-2009-07-235960 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   Thomas H. Chase, Bonnie L. Lyons, Roderick T. Bronson, Oded Foreman, Leah Rae Donahue, Lisa M. Burzenski, Bruce Gott, Priscilla Lane, Belinda Harris, Uta Ceglarek, Joachim Thiery, Henning Wittenburg, Jonathan N. Thon, Joseph E. Italiano Jr, Kenneth R. Johnson, and Leonard D. Shultz The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia Blood First Edition Paper, prepublished online October 21, 2009; DOI 10.1182/blood-2009-05-219808 [Abstract] [Full Text] [PDF]   Marta Lionetti, Marta Biasiolo, Luca Agnelli, Katia Todoerti, Laura Mosca, Sonia Fabris, Gabriele Sales, Giorgio Lambertenghi Deliliers, Silvio Bicciato, Luigia Lombardi, Stefania Bortoluzzi, and Antonino Neri Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma Blood First Edition Paper, prepublished online October 21, 2009; DOI 10.1182/blood-2009-08-237495 [Abstract] [Full Text] [PDF]   Drew Provan, Roberto Stasi, Adrian C. Newland, Victor S. Blanchette, Paula Bolton-Maggs, James B. Bussel, Beng H. Chong, Douglas B. Cines, Terry B. Gernsheimer, Bertrand Godeau, John Grainger, Ian Greer, Beverley J. Hunt, Paul A. Imbach, Gordon Lyons, Robert McMillan, Francesco Rodeghiero, Miguel A. Sanz, Michael Tarantino, Shirley Watson, Joan Young, and David J. Kuter International consensus report on the investigation and management of primary immune thrombocytopenia Blood First Edition Paper, prepublished online October 21, 2009; DOI 10.1182/blood-2009-06-225565 [Abstract] [Full Text] [PDF] [Supplemental Appendices]   20 October 2009 Michael R. Grever How I treat hairy cell leukemia Blood First Edition Paper, prepublished online October 20, 2009; DOI 10.1182/blood-2009-06-195370 [Abstract] [Full Text] [PDF]   Christiane L. Belele, Milton A. English, Jagman Chahal, Anthony Burnetti, Steven M. Finckbeiner, Gretchen Gibney, Martha Kirby, Raman Sood, and Paul Liu Differential requirement for Gata1 DNA binding and transactivation between primitive and definitive stages of hematopoiesis in zebrafish Blood First Edition Paper, prepublished online October 20, 2009; DOI 10.1182/blood-2009-05-224709 [Abstract] [Full Text] [PDF]   Ronen Ben-Ami, Russell E. Lewis, Konstantinos Leventakos, and Dimitrios P. Kontoyiannis Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites Blood First Edition Paper, prepublished online October 20, 2009; DOI 10.1182/blood-2009-07-231209 [Abstract] [Full Text] [PDF]   Christoph Bucher, Lisa Jasperson, Christine Vogtenhuber, Emily Goren, Meghan Munger, Angela Panoskaltsis-Mortari, Pallavur Sivakumar, and Bruce R. Blazar IL-21 blockade reduces graft-versus-host-disease mortality by supporting inducible T regulatory cell generation Blood First Edition Paper, prepublished online October 20, 2009; DOI 10.1182/blood-2009-05-221135 [Abstract] [Full Text] [PDF]   Geraldine Blanchard-Rohner, Anoop S. Pulickal, Cornelia M. Jol-van der Zijde, Matthew D. Snape, and Andrew J. Pollard Appearance of peripheral blood plasma cells and memory B-cells in a primary and secondary immune response in humans Blood First Edition Paper, prepublished online October 20, 2009; DOI 10.1182/blood-2009-03-211052 [Abstract] [Full Text] [PDF]   Franck E. Nicolini, Michael J. Mauro, Giovanni Martinelli, Dong-Wook Kim, Simona Soverini, Martin C. Muller, Andreas Hochhaus, Jorge Cortes, Charles Chuah, Inge H. Dufva, Jane F. Apperley, Fumiharu Yagasaki, Jay D. Pearson, Senaka Peter, Cesar Sanz Rodriguez, Claude Preudhomme, Francis Giles, John M. Goldman, and Wei Zhou Epidemiological study on survival of chronic myeloid leukemia (CML) and Ph+ acute lymphoblastic leukemia (ALL) patients with BCR-ABL T315I mutation Blood First Edition Paper, prepublished online October 20, 2009; DOI 10.1182/blood-2009-04-219410 [Abstract] [Full Text] [PDF]   John C. Byrd, Thomas J. Kipps, Ian W. Flinn, Januaro Castro, Thomas S. Lin, William Wierda, Nyla Heerema, James Woodworth, Steve Hughes, Shabnam Tangri, Sarah Harris, Dee Wynne, Arturo Molina, Bryan Leigh, and Susan O'Brien Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia Blood First Edition Paper, prepublished online October 20, 2009; DOI 10.1182/blood-2009-08-237727 [Abstract] [Full Text] [PDF]   Pier M. Mannucci, Roger E.G. Schutgens, Elena Santagostino, and Evelien P. Mauser-Bunschoten How I treat age-related morbidities in elderly persons with hemophilia Blood First Edition Paper, prepublished online October 20, 2009; DOI 10.1182/blood-2009-07-215665 [Abstract] [Full Text] [PDF]   16 October 2009 Shannon K. McWeeney, Lucy C. Pemberton, Marc M. Loriaux, Kristina Vartanian, Stephanie G. Willis, Gregory Yochum, Beth Wilmot, Yaron Turpaz, Raji Pillai, Brian J. Druker, Jennifer L. Snead, Mary MacPartlin, Stephen G. O'Brien, Junia V. Melo, Thoralf Lange, Christina A. Harrington, and Michael W. Deininger A gene expression signature of CD34+ cells to predict major cytogenetic response in chronic phase chronic myeloid leukemia patients treated with imatinib Blood First Edition Paper, prepublished online October 16, 2009; DOI 10.1182/blood-2009-03-210732 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Faten Bougaten, Cathy Quemener, Sabrina Kellouche, Benyoussef Naimi, Marie-Pierre Podgorniak, Guy Millot, Eric E Gabison, Fabien Calvo, Christine Dosquet, Celeste Lebbe, Suzanne Menashi, and Samia Mourah EMMPRIN promotes angiogenesis through HIF-2 mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2 Blood First Edition Paper, prepublished online October 16, 2009; DOI 10.1182/blood-2009-04-217380 [Abstract] [Full Text] [PDF]   Anne-Marit Sponaas, Ana Paula Freitas do Rosario, Cecile Voisine, Beatris Mastelic, Joanne Thompson, Sandra Koernig, William Jarra, Laurent Renia, Marjorie Mauduit, Alexandre Potocnik, and Jean Langhorne Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria Blood First Edition Paper, prepublished online October 16, 2009; DOI 10.1182/blood-2009-04-217489 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Lijuan Chen, Siqing Wang, Yiming Zhou, Xiaosong Wu, Igor Entin, Joshua Epstein, Shmuel Yaccoby, Wei Xiong, Bart Barlogie, John D. Shaughnessy Jr, and Fenghuang Zhan Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma Blood First Edition Paper, prepublished online October 16, 2009; DOI 10.1182/blood-2009-03-210526 [Abstract] [Full Text] [PDF]   14 October 2009 Nicholas T. Funderburg, Elizabeth Mayne, Scott F. Sieg, Robert Asaad, Wei Jiang, Magdalena Kalinowska, Angel A. Luciano, Wendy Stevens, Benigno Rodriguez, Jason M. Brenchley, Daniel C. Douek, and Michael M. Lederman Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-03-210179 [Abstract] [Full Text] [PDF]   Huei-Ting Tsai, Neil E. Caporaso, Robert A. Kyle, Jerry A. Katzmann, Angela Dispenzieri, Richard B. Hayes, Gerald E Marti, Maher Albitar, Paolo Ghia, S. Vincent Rajkumar, and Ola Landgren Evidence of serum immunoglobulin abnormalities up to 9.8 years prior to diagnosis of chronic lymphocytic leukemia: a prospective study Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-08-237651 [Abstract] [Full Text] [PDF]   Bohua Li, Lei Zhao, Huaizu Guo, Chong Wang, Xunming Zhang, Lan Wu, Lin Chen, Qing Tong, Weizhu Qian, Hao Wang, and Yajun Guo Characterization of a rituximab variant with potent antitumor activity against rituximab-resistant B-cell lymphoma Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-06-225474 [Abstract] [Full Text] [PDF]   Tho Pham, Christopher J. Gregg, Felix Karp, Renee Chow, Vered Padler-Karavani, Hongzhi Cao, Xi Chen, Joseph L. Witztum, Nissi M. Varki, and Ajit Varki Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-05-220400 [Abstract] [Full Text] [PDF]   Yongchao Wang, Warren Fiskus, Daniel G. Chong, Kathleen M. Buckley, Kavita Natarajan, Rekha Rao, Atul Joshi, Ramesh Balusu, Sanjay Koul, Jianguang Chen, Andrew Savoie, Celalettin Ustun, Anand P. Jillella, Peter Atadja, Ross L. Levine, and Kapil N. Bhalla Co-treatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplasm cells Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-05-222133 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Andrew D Mumford, Ban B Dawood, Martina E Daly, Sherina L Murden, Michael D Williams, Majd B Protty, Jennifer C Spalton, Mark Wheatley, Stuart J Mundell, and Steve P Watson A novel thromboxane A2 receptor D304N variant which abrogates ligand binding in a patient with a bleeding diathesis Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-08-236976 [Abstract] [Full Text] [PDF]   David I. Marks, Elisabeth M. Paietta, Anthony V. Moorman, Susan M. Richards, Georgina Buck, Gordon DeWald, Adolfo Ferrando, Adele K. Fielding, Anthony H Goldstone, Rhett P. Ketterling, Mark R. Litzow, Selina M. Luger, Andrew K. McMillan, Marc Mansour, Jacob M. Rowe, Martin S. Tallman, and Hillard M. Lazarus T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics and outcome from the large randomised prospective trial (UKALL XII/ECOG 2993) Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-08-231217 [Abstract] [Full Text] [PDF] [Supplemental Methods]   Eva M. Trinidad, Monica Ballesteros, Jaime Zuloaga, Agustin Zapata, and Luis M. Alonso-Colmenar An impaired transendothelial migration potential of chronic lymphocytic leukemia cells can be linked to ephrin-A4 expression Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-03-210617 [Abstract] [Full Text] [PDF]   Rafijul Bari, Teresa Bell, Wai-Hang Leung, Queenie P. Vong, Wing Keung Chan, Neha Das Gupta, Martha Holladay, Barbara Rooney, and Wing Leung Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of Arginine245 Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-07-231977 [Abstract] [Full Text] [PDF]   Lisa K Jasperson, Christoph Bucher, Angela Panoskaltsis-Mortari, Andrew L Mellor, David H Munn, and Bruce R Blazar Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-06-227587 [Abstract] [Full Text] [PDF]   Maaike Luesink, Jeroen L. A. Pennings, Willemijn M. Wissink, Peter C.M. Linssen, Petra Muus, Rolph Pfundt, Theo J. M. de Witte, Bert A. van der Reijden, and Joop H. Jansen Chemokine induction by all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia - triggering the differentiation syndrome Blood First Edition Paper, prepublished online October 14, 2009; DOI 10.1182/blood-2009-02-204834 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   12 October 2009 Daniel Corcos, Michael J. Osborn, Louise S. Matheson, Fatima Santos, Xiangang Zou, Jennifer A. Smith, Geoff Morgan, Amanda Hutchings, Maureen Hamon, David Oxley, and Marianne Bruggemann Immunoglobulin aggregation leading to Russell body formation is prevented by the antibody light chain Blood First Edition Paper, prepublished online October 12, 2009; DOI 10.1182/blood-2009-07-234864 [Abstract] [Full Text] [PDF] [Supplemental Table and Figure]   Gianantonio Rosti, Francesca Palandri, Fausto Castagnetti, Massimo Breccia, Luciano Levato, Gabriele Gugliotta, Adele Capucci, Michele Cedrone, Carmen Fava, Tamara Intermesoli, Giovanna Rege Cambrin, Fabio Stagno, Mario Tiribelli, Marilina Amabile, Simona Luatti, Angela Poerio, Simona Soverini, Nicoletta Testoni, Giovanni Martinelli, Giuliana Alimena, Fabrizio Pane, Giuseppe Saglio, and Michele Baccarani Nilotinib for the frontline treatment of Ph+ chronic myeloid leukemia Blood First Edition Paper, prepublished online October 12, 2009; DOI 10.1182/blood-2009-07-232595 [Abstract] [Full Text] [PDF]   Nancy A. Turner, Leticia Nolasco, Zaverio M. Ruggeri, and Joel L. Moake Endothelial cell ADAMTS-13 and VWF: production, release and VWF string cleavage Blood First Edition Paper, prepublished online October 12, 2009; DOI 10.1182/blood-2009-07-231597 [Abstract] [Full Text] [PDF]   Lesleigh S. Abbott, Mariana Deevska, Conrad V. Fernandez, David Dix, Victoria E. Price, Hao Wang, Louise Parker, Margaret Yhap, Colleen Fitzgerald, Dorothy R. Barnard, and Jason N. Berman The impact of prophylactic fresh frozen plasma and cryoprecipitate on the incidence of CNS thrombosis and hemorrhage in children with acute lymphoblastic leukemia receiving asparaginase Blood First Edition Paper, prepublished online October 12, 2009; DOI 10.1182/blood-2009-07-231084 [Abstract] [Full Text] [PDF]   Jonathan A Gutman, Cameron J Turtle, Thomas J Manley, Shelly Heimfeld, Irwin D Bernstein, Stanley R Riddell, and Colleen Delaney Single unit dominance following double unit umbilical cord blood transplantation coincides with a specific CD8+ T cell response against the non-engrafted unit Blood First Edition Paper, prepublished online October 12, 2009; DOI 10.1182/blood-2009-07-228999 [Abstract] [Full Text] [PDF]   Amber N. Stratman, Kristine M. Malotte, Rachel D. Mahan, Michael J. Davis, and George E. Davis Pericyte recruitment during vasculogenic tube assemblystimulates endothelial basement membrane matrix formation Blood First Edition Paper, prepublished online October 12, 2009; DOI 10.1182/blood-2009-05-222364 [Abstract] [Full Text] [PDF] [Supplemental Tables, Figures, and Videos]   Enjing Jin, Ju Liu, Jun-ichi Suehiro, Lei Yuan, Yoshiaki Okada, Vesna Nikolova-Krstevski, Kiichiro Yano, Lauren Janes, David Beeler, Katherine C. Spokes, Dan Li, Erzsebet Regan, Shou-Ching Shih, Peter Oettgen, Takashi Minami, and William C. Aird Differential roles for ETS, CREB and EGR binding sites in mediating VEGF receptor 1 expression in vivo Blood First Edition Paper, prepublished online October 12, 2009; DOI 10.1182/blood-2009-05-220434 [Abstract] [Full Text] [PDF]   Erin A. Kimbrel, Madeleine E. Lemieux, Xiaobo Xia, Tina N. Davis, Vivienne I. Rebel, and Andrew L. Kung Systematic in vivo structure-function analysis of p300 in hematopoiesis Blood First Edition Paper, prepublished online October 12, 2009; DOI 10.1182/blood-2009-04-217794 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Raewyn Broady, Jie Yu, and Megan K. Levings ATG-induced expression of FOXP3 in human CD4+ T cells in vitro is associated with T cell activation and not the induction of FOXP3+ T regulatory cells Blood First Edition Paper, prepublished online October 12, 2009; DOI 10.1182/blood-2009-04-214437 [Abstract] [Full Text] [PDF]   7 October 2009 Zhao-Yang Wang, Ye-Xiong Li, Wei-Hu Wang, Jing Jin, Hua Wang, Yong-Wen Song, Qing-Feng Liu, Shu-Lian Wang, Yue-Ping Liu, Shu-Nan Qi, Hui Fang, Xin-Fan Liu, and Zi-Hao Yu Primary radiotherapy showed favorable outcome in treating extranodal nasal-type NK/T-cell lymphoma in children and adolescents Blood First Edition Paper, prepublished online October 7, 2009; DOI 10.1182/blood-2009-07-235853 [Abstract] [PDF]   Dalemari Crowther-Swanepoel, Mobshra Qureshi, Martin J. S. Dyer, Estella Matutes, Claire Dearden, Daniel Catovsky, and Richard S. Houlston Genetic variation in CXCR4 and risk of chronic lymphocytic leukemia Blood First Edition Paper, prepublished online October 7, 2009; DOI 10.1182/blood-2009-07-235184 [Abstract] [PDF]   Nicolaus Kroger, Ernst Holler, Guido Kobbe, Martin Bornhaeuser, Rainer Schwerdtfeger, Herrad Baurmann, Arnon Nagler, Wolfgang Bethge, Matthias Stelljes, Lutz Uharek, Hannes Wandt, Andreas Burchert, Paolo Corradini, Jorg Schubert, Martin Kaufmann, Peter Dreger, Gerald G. Wulf, Hermann Einsele, Tatjana Zabelina, Hans Michael Kvasnicka, Juergen Thiele, Ronald Brand, Axel R. Zander, Dietger Niederwieser, and Theo M. de Witte Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT) Blood First Edition Paper, prepublished online October 7, 2009; DOI 10.1182/blood-2009-07-234880 [Abstract] [PDF]   Sandra Duber, Martin Hafner, Martina Krey, Stefan Lienenklaus, Bishnudeo Roy, Elias Hobeika, Michael Reth, Thorsten Buch, Ari Waisman, Karsten Kretschmer, and Siegfried Weiss Induction of B cell development in adult mice reveals the ability of bone marrow to produce B-1a cells Blood First Edition Paper, prepublished online October 7, 2009; DOI 10.1182/blood-2009-04-218156 [Abstract] [PDF] [Supplemental Table and Figures]   Junmei Chen, Xiaoyun Fu, Yi Wang, Minhua Ling, Brad McMullen, John Kulman, Dominic W. Chung, and Jose A. Lopez Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13 Blood First Edition Paper, prepublished online October 7, 2009; DOI 10.1182/blood-2009-03-213967 [Abstract] [PDF]   Thomas H Sisson, Mai-Huong Nguyen, Bi Yu, Margaret L Novak, Richard H Simon, and Timothy J Koh Urokinase-type plasminogen activator increases hepatocyte growth factor activity required for skeletal muscle regeneration Blood First Edition Paper, prepublished online October 7, 2009; DOI 10.1182/blood-2008-12-196212 [Abstract] [PDF]   6 October 2009 Jose A. Guerrero, Mark Kyei, Susan Russell, Junling Liu, T. Kent Gartner, Brian Storrie, and Jerry Ware Visualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation Blood First Edition Paper, prepublished online October 6, 2009; DOI 10.1182/blood-2009-03-210823 [Abstract] [PDF]   Jih-Luh Tang, Hsin-An Hou, Chien-Yuan Chen, Chieh-Yu Liu, Wen-Chien Chou, Mei-Hsuan Tseng, Chi-Fei Huang, Fen-Yu Lee, Ming-Chih Liu, Ming Yao, Shang-Yi Huang, Bor-Sheng Ko, Szu-Chun Hsu, Shang-Ju Wu, Woei Tsay, Yao-Chang Chen, Liang-In Lin, and Hwei-Fang Tien AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations Blood First Edition Paper, prepublished online October 6, 2009; DOI 10.1182/blood-2009-05-223784 [Abstract] [PDF]   Goichi Yoshimoto, Toshihiro Miyamoto, Siamak Jabbarzadeh-Tabrizi, Tadafumi Iino, Jennifer L. Rocnik, Yoshikane Kikushige, Yasuo Mori, Takahiro Shima, Hiromi Iwasaki, Katsuto Takenaka, Koji Nagafuji, Shin-ichi Mizuno, Hiroaki Niiro, Gary D. Gilliland, and Koichi Akashi FLT3-ITD upregulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation Blood First Edition Paper, prepublished online October 6, 2009; DOI 10.1182/blood-2008-12-196055 [Abstract] [PDF]   5 October 2009 Hezder E. van Nispen tot Pannerden, Suzanne M. van Dijk, Vivian Du, and Harry F.G. Heijnen Platelet protein disulfide isomerase is localized in the dense tubular system and does not become surface expressed after activation Blood First Edition Paper, prepublished online October 5, 2009; DOI 10.1182/blood-2009-03-210450 [Abstract] [PDF] [Supplemental Figures]   Jeffrey M. Milush, Brian R. Long, Jennifer E. Snyder-Cappione, Amedeo J. Cappione III, Vanessa A. York, Lishomwa C. Ndhlovu, Lewis L. Lanier, Jakob L. Michaelsson, and Douglas F. Nixon Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by co-expression of CD56, CD7, and CD4 Blood First Edition Paper, prepublished online October 5, 2009; DOI 10.1182/blood-2009-04-216374 [Abstract] [PDF]   Nicolas Gaudenzio, Nicolas Espagnole, Lennart T. Mars, Roland Liblau, Salvatore Valitutti, and Eric Espinosa Cell-cell cooperation at the T helper cell/mast cell immunological synapse Blood First Edition Paper, prepublished online October 5, 2009; DOI 10.1182/blood-2009-02-202648 [Abstract] [PDF]   Marina P. Sikara, John G. Routsias, Martina Samiotaki, George Panayotou, Haralampos M. Moutsopoulos, and Panayiotis G. Vlachoyiannopoulos 2 glycoprotein I (2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome Blood First Edition Paper, prepublished online October 5, 2009; DOI 10.1182/blood-2009-03-206367 [Abstract] [PDF]   Jason A. Powell, Daniel Thomas, Emma F. Barry, Chung H. Kok, Barbara J. McClure, Anna Tsykin, L. Bik To, Anna Brown, Ian D. Lewis, Kirsten Herbert, Gregory J. Goodall, Terence P. Speed, Norio Asou, Bindya Jacob, Motomi Osato, David N. Haylock, Susan K. Nilsson, Richard J. D'Andrea, Angel F. Lopez, and Mark A. Guthridge Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML Blood First Edition Paper, prepublished online October 5, 2009; DOI 10.1182/blood-2009-02-204818 [Abstract] [PDF]   Siao-Yi Wang, Suresh Veeramani, Emilian Racila, Jeffrey Cagley, David Fritzinger, Carl-Wilhelm Vogel, William St. John, and George J. Weiner Depletion of the C3 component of complement enhances the ability of rituximab-coated target cells to activate human NK cells and improves the efficacy of monoclonal antibody therapy in an in vivo model Blood First Edition Paper, prepublished online October 5, 2009; DOI 10.1182/blood-2009-01-200469 [Abstract] [PDF]   2 October 2009 Kunju Sridhar, Douglas T. Ross, Robert Tibshirani, Atul J. Butte, and Peter L. Greenberg Relationship of differential gene expression profiles in CD34+ myelodysplastic syndrome marrow cells to disease subtype and progression Blood First Edition Paper, prepublished online October 2, 2009; DOI 10.1182/blood-2009-08-236422 [Abstract] [PDF]   Arnaud Gandillet, Alicia G. Serrano, Stella Pearson, Michael Lie-A-Ling, Georges Lacaud, and Valerie Kouskoff Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification Blood First Edition Paper, prepublished online October 2, 2009; DOI 10.1182/blood-2009-06-226290 [Abstract] [PDF]   Stefan Kunert, Imke Meyer, Silke Fleischhauer, Martin Wannack, Janine Fiedler, Ramesh A. Shivdasani, and Harald Schulze The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation Blood First Edition Paper, prepublished online October 2, 2009; DOI 10.1182/blood-2009-04-216804 [Abstract] [PDF] [Supplemental Figure]   1 October 2009 Julie A. Vrana, Jeffrey D Gamez, Benjamin J. Madden, Jason D. Theis, H. Robert Bergen III, and Ahmet Dogan Classification of amyloidosis by laser microdissection and mass spectrometry based proteomic analysis in clinical biopsy specimens Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2009-07-230722 [Abstract] [PDF] [Supplemental Methods, Tables, Figures, and Video]   Nicoletta Testoni, Giulia Marzocchi, Simona Luatti, Marilina Amabile, Carmen Baldazzi, Monica Stacchini, Mauro Nanni, Giovanna Rege-Cambrin, Emilia Giugliano, Ursula Giussani, Elisabetta Abruzzese, Simonetta Kerim, Maria Grazia Grimoldi, Alessandro Gozzetti, Barbara Crescenzi, Carlo Carcassi, Paolo Bernasconi, Antonio Cuneo, Francesco Albano, Giuseppina Fugazza, Alfonso Zaccaria, Giovanni Martinelli, Fabrizio Pane, Gianantonio Rosti, and Michele Baccarani Chronic myeloid leukemia: a prospective comparison of interphase fluorescence in situ hybridization and chromosome banding analysis for the definition of complete cytogenetic response, a study of the GIMEMA CML WP Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2009-07-229864 [Abstract] [PDF]   Martin S. Tallman and Jessica K. Altman How I treat acute promyelocytic leukemia Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2009-07-216457 [Abstract] [PDF]   Robert A. Campbell, Katherine A. Overmyer, Craig H. Selzman, Brett C. Sheridan, and Alisa S. Wolberg Contributions of extravascular and intravascular cells to fibrin network formation, structure, and stability Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2009-06-228940 [Abstract] [PDF]   Carlos Fernandez de Larrea, Maria Teresa Cibeira, Montserrat Elena, Juan Ignacio Arostegui, Laura Rosinol, Montserrat Rovira, Xavier Filella, Jordi Yague, and Joan Blade Abnormal serum free light chain ratio in patients with multiple myeloma in complete remission has strong association with the presence of oligoclonal bands: implications for stringent complete remission definition Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2009-06-224832 [Abstract] [PDF]   Daniel Lewandowski, Vilma Barroca, Frederic Duconge, Jan Bayer, Jeanne Tran Van Nhieu, Carine Pestourie, Pierre Fouchet, Bertrand Tavitian, and Paul-Henri Romeo In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2009-05-222711 [Abstract] [PDF]   Luis A. Verduzco and David G. Nathan Sickle cell disease and stroke Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2009-05-220921 [Abstract] [PDF]   Jessica A. Van Ziffle and Clifford A. Lowell Neutrophil specific deletion of Syk kinase results in reduced host defense to bacterial infection Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2009-05-220806 [Abstract] [PDF] [Supplemental Methods and Figures]   Zhaohui Ye, Huichun Zhan, Prashant Mali, Sarah Dowey, Donna M. Williams, Yoon-Young Jang, Chi V. Dang, Jerry L. Spivak, Alison R. Moliterno, and Linzhao Cheng Human induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2009-04-217406 [Abstract] [PDF]   Florence C. Guibal, Meritxell Alberich-Jorda, Hideyo Hirai, Alexander Ebralidze, Elena Levantini, Annalisa Di Ruscio, Pu Zhang, Barbara A. Santana-Lemos, Donna Neuberg, Amy J. Wagers, Eduardo M. Rego, and Daniel G. Tenen Identification of a myeloid committed progenitor as the cancer initiating cell in acute promyelocytic leukemia Blood First Edition Paper, prepublished online October 1, 2009; DOI 10.1182/blood-2008-10-182071 [Abstract] [PDF] [Supplemental Methods, Tables, and Figures]   30 September 2009 Maria I. Mascarenhas, Aimee Parker, Elaine Dzierzak, and Katrin Ottersbach Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling Blood First Edition Paper, prepublished online September 30, 2009; DOI 10.1182/blood-2009-06-230037 [Abstract] [PDF]   Xiao-juan Zhu, Yan Shi, Jun Peng, Cheng-shan Guo, Ning-ning Shan, Ping Qin, Xue-bin Ji, and Ming Hou The effects of BAFF and BAFF-R-Fc fusion protein in immune thrombocytopenia Blood First Edition Paper, prepublished online September 30, 2009; DOI 10.1182/blood-2009-05-217513 [Abstract] [PDF]   Andrea Annoni, Brian D Brown, Alessio Cantore, Lucia Sergi Sergi, Luigi Naldini, and Maria-Grazia Roncarolo In vivo delivery of a microRNA regulated transgene induces antigen-specific regulatory T cells and promotes immunological tolerance Blood First Edition Paper, prepublished online September 30, 2009; DOI 10.1182/blood-2009-04-214569 [Abstract] [PDF]   Jonathan Skupsky, Ai-Hong Zhang, Yan Su, and David W. Scott A role for thrombin in the initiation of the immune response to therapeutic Factor VIII Blood First Edition Paper, prepublished online September 30, 2009; DOI 10.1182/blood-2008-10-186452 [Abstract] [PDF]   29 September 2009 Jordan A. Shavit, Ani Manichaikul, Heidi L. Lemmerhirt, Karl W. Broman, and David Ginsburg Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice Blood First Edition Paper, prepublished online September 29, 2009; DOI 10.1182/blood-2009-07-233213 [Abstract] [PDF]   Carlo Calissano, Rajendra N. Damle, Gregory Hayes, Elizabeth J. Murphy, Marc K. Hellerstein, Carol Moreno, Cristina Sison, Matthew S. Kaufman, Jonathan E. Kolitz, Steven L. Allen, Kanti R. Rai, and Nicholas Chiorazzi In vivo intra- and inter-clonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia Blood First Edition Paper, prepublished online September 29, 2009; DOI 10.1182/blood-2009-05-219634 [Abstract] [PDF]   Alexander Nystrom, Zabeena P. Shaik, Donald Gullberg, Thomas Krieg, Beate Eckes, Roy Zent, Ambra Pozzi, and Renato V. Iozzo Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity Blood First Edition Paper, prepublished online September 29, 2009; DOI 10.1182/blood-2009-02-207134 [Abstract] [PDF]   Kate A Markey, Angela C Burman, Tatjana Banovic, Rachel D Kuns, Neil C Raffelt, Vanessa Rowe, Stuart D Olver, Alistair LJ Don, Edward S Morris, Allison R Pettit, Yana A Wilson, Renee J Robb, Louise M Randall, Heinrich Korner, Christian R Engwerda, Andrew D Clouston, Kelli PA MacDonald, and Geoffrey R Hill Soluble lymphotoxin is an important effector molecule in GVHD and GVL Blood First Edition Paper, prepublished online September 29, 2009; DOI 10.1182/blood-2009-01-199927 [Abstract] [PDF]   28 September 2009 Hendrik B. Feys, Inge Pareyn, Renee Vancraenenbroeck, Marc De Maeyer, Hans Deckmyn, Chris Van Geet, and Karen Vanhoorelbeke Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease domain reduces secretion and substrate turnover in a patient with congenital thrombotic thrombocytopenic purpura Blood First Edition Paper, prepublished online September 28, 2009; DOI 10.1182/blood-2009-07-230615 [Abstract] [PDF]   Alan G. Ramsay, Andrew J. Clear, Gavin Kelly, Rewas Fatah, Janet Matthews, Finlay MacDougall, T. Andrew Lister, Abigail M. Lee, Maria Calaminici, and John G. Gribben Follicular lymphoma cells induce T-cell immunological synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy Blood First Edition Paper, prepublished online September 28, 2009; DOI 10.1182/blood-2009-04-217687 [Abstract] [PDF]   Wahid Boukouaci, Marc Busson, Regis Peffault de Latour, Vanderson Rocha, Caroline Suberbielle, Djaouida Bengoufa, Nicolas Dulphy, Philippe Haas, Catherine Scieux, Habiba Amroun, Eliane Gluckman, Rajagopal Krishnamoorthy, Antoine Toubert, Dominique Charron, Gerard Socie, and Ryad Tamouza MICA-129 genotype, soluble MICA and anti-MICA antibodies as biomarkers of chronic graft versus host disease Blood First Edition Paper, prepublished online September 28, 2009; DOI 10.1182/blood-2009-04-217430 [Abstract] [PDF]   John M. Pagel, Theodore A. Gooley, Joseph Rajendran, Darrell R. Fisher, Wendy A. Wilson, Brenda M. Sandmaier, Dana C. Matthews, H. Joachim Deeg, Ajay K. Gopal, Paul J. Martin, Rainer F. Storb, Oliver W. Press, and Frederick R. Appelbaum Allogeneic hematopoietic cell transplantation after conditioning with 131I-anti-CD45 antibody plus fludarabine and low-dose total body irradiation for elderly patients with advanced acute myeloid leukemia or high-risk myelodysplastic syndrome Blood First Edition Paper, prepublished online September 28, 2009; DOI 10.1182/blood-2009-03-213298 [Abstract] [PDF]   Jennifer L. Costantini, Samuel M.S. Cheung, Sen Hou, Hongzhao Li, Sam K. Kung, James B. Johnston, John A. Wilkins, Spencer B. Gibson, and Aaron J. Marshall TAPP2 links phosphoinositide 3-kinase signaling to B cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B cell leukemia Blood First Edition Paper, prepublished online September 28, 2009; DOI 10.1182/blood-2009-03-213058 [Abstract] [PDF] [Supplemental Figures]   24 September 2009 Akiko Kimura, Michael A Rieger, James M Simone, Weiping Chen, Mark C Wickre, Bing-Mei Zhu, Philipp S Hoppe, John J O'Shea, Timm Schroeder, and Lothar Hennighausen The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis Blood First Edition Paper, prepublished online September 24, 2009; DOI 10.1182/blood-2009-04-216390 [Abstract] [PDF] [Supplemental Tables, Figures, and Videos]   Martin C Muller, Jorge E Cortes, Dong-Wook Kim, Brian J Druker, Philipp Erben, Ricardo Pasquini, Susan Branford, Timothy P Hughes, Jerald P Radich, Lynn Ploughman, Jaydip Mukhopadhyay, and Andreas Hochhaus Dasatinib treatment of chronic phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations Blood First Edition Paper, prepublished online September 24, 2009; DOI 10.1182/blood-2009-04-214221 [Abstract] [PDF] [Supplemental Table]   Heinz Laubli, Katharina-Susanne Spanaus, and Lubor Borsig Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes Blood First Edition Paper, prepublished online September 24, 2009; DOI 10.1182/blood-2008-10-186585 [Abstract] [PDF] [Supplemental Table and Figures] [Additional Supplemental Figures]   23 September 2009 Phillip Scheinberg, Jan J. Melenhorst, Jason M. Brenchley, Brenna J. Hill, Nancy F. Hensel, Pratip K. Chattopadhyay, Mario Roederer, Louis J. Picker, David A. Price, A. John Barrett, and Daniel C. Douek The transfer of adaptive immunity to cytomegalovirus (CMV) during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor Blood First Edition Paper, prepublished online September 23, 2009; DOI 10.1182/blood-2009-04-214684 [Abstract] [PDF]   22 September 2009 Dmitri V. Gnatenko, Wei Zhu, Xiao Xu, Edward T. Samuel, Melissa Monaghan, Mohammad H. Zarrabi, Christi Kim, Anil Dhundale, and Wadie F. Bahou Class prediction models of thrombocytosis using genetic biomarkers Blood First Edition Paper, prepublished online September 22, 2009; DOI 10.1182/blood-2009-05-224477 [Abstract] [PDF]   Martina Tremmel, Alexandra Matzke, Imke Albrecht, Anna M. Laib, Vivienne Olaku, Kurt Ballmer-Hofer, Gerhard Christofori, Melanie Heroult, Hellmut G. Augustin, Helmut Ponta, and Veronique Orian-Rousseau A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis Blood First Edition Paper, prepublished online September 22, 2009; DOI 10.1182/blood-2009-04-219204 [Abstract] [PDF]   Elisa Cantarelli, Raffaella Melzi, Alessia Mercalli, Valeria Sordi, Giuliana Ferrari, Carsten Werner Lederer, Emanuela Mrak, Alessandro Rubinacci, Maurilio Ponzoni, Giovanni Sitia, Luca G. Guidotti, Ezio Bonifacio, and Lorenzo Piemonti Bone marrow as an alternative site for islet transplantation Blood First Edition Paper, prepublished online September 22, 2009; DOI 10.1182/blood-2009-03-209973 [Abstract] [PDF] [Supplemental Table and Figures]   Mohamed Rahmani, Anh Anderson, Joseph Reza Habibi, Timothy Ryan Crabtree, Mandy Mayo, Hisashi Harada, Andrea Ferreira-Gonzalez, Paul Dent, and Steven Grant The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathways Blood First Edition Paper, prepublished online September 22, 2009; DOI 10.1182/blood-2008-09-177881 [Abstract] [PDF] [Supplemental Table and Figures]   21 September 2009 Marco Herling, Kaushali A Patel, Nicole Weit, Nils Lilienthal, Michael Hallek, Michael J Keating, and Dan Jones High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia Blood First Edition Paper, prepublished online September 21, 2009; DOI 10.1182/blood-2009-03-208256 [Abstract] [PDF] [Supplemental Table]   Yasushi Kubota, Masatake Osawa, Lars Martin Jakt, Kazuaki Yoshikawa, and Shin-Ichi Nishikawa Necdin restricts proliferation of hematopoietic stem cells during hematopoietic regeneration Blood First Edition Paper, prepublished online September 21, 2009; DOI 10.1182/blood-2009-07-230292 [Abstract] [PDF]   Jennifer Brewin, Christoph Mancao, Karin Straathof, Helen Karlsson, Sujith Samarasinghe, Persis J. Amrolia, and Martin Pule Generation of EBV-specific cytotoxic T-cells that are resistant to calcineurin inhibitors for the treatment of post-transplant lymphoproliferative disease Blood First Edition Paper, prepublished online September 21, 2009; DOI 10.1182/blood-2009-07-228387 [Abstract] [PDF] [Supplemental Figures]   Denise E. Sabatino, Christian Furlan Freguia, Raffaella Toso, Andrey Santos, Elizabeth P. Merricks, Haig H. Kazazian Jr., Timothy C. Nichols, Rodney M. Camire, and Valder R. Arruda Recombinant canine B-domain deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model Blood First Edition Paper, prepublished online September 21, 2009; DOI 10.1182/blood-2009-05-220327 [Abstract] [PDF]   Baowei Peng, Peiqing Ye, David J. Rawlings, Hans D. Ochs, and Carol H. Miao Anti-CD3 antibodies modulate anti-factor VIII immune responses in hemophilia A mice after factor VIII plasmid-mediated gene therapy Blood First Edition Paper, prepublished online September 21, 2009; DOI 10.1182/blood-2009-05-217315 [Abstract] [PDF]   18 September 2009 Sandra J. Horning, Malik E. Juweid, Heiko Schoder, Gregory Wiseman, Alex McMillan, Lode J. Swinnen, Ranjana Advani, Randy Gascoyne, and Andrew Quon Interim positron emission tomography (PET) scans in diffuse large B-cell lymphoma: an independent expert nuclear medicine evaluation of the Eastern Cooperative Oncology Group E3404 study Blood First Edition Paper, prepublished online September 18, 2009; DOI 10.1182/blood-2009-08-234351 [Abstract] [PDF]   Bethan Psaila, Aleksandra Petrovic, Lemke K. Page, Jill Menell, Matthew Schonholz, and James B. Bussel Intracranial hemorrhage (ICH) in children with immune thrombocytopenia (ITP): study of 40 cases Blood First Edition Paper, prepublished online September 18, 2009; DOI 10.1182/blood-2009-04-215525 [Abstract] [PDF]   Morgan Taillardet, Ghina Haffar, Paul Mondiere, Marie-Jeanne Asensio, Hanane Gheit, Nicolas Burdin, Thierry Defrance, and Laurent Genestier The thymus-independent immunity conferred by a pneumococcal polysaccharide is mediated by long-lived plasma cells Blood First Edition Paper, prepublished online September 18, 2009; DOI 10.1182/blood-2009-01-200014 [Abstract] [PDF]   Kristin Hochweller, Tewfik Miloud, Jorg Striegler, Shalin Naik, Gunter J. Hammerling, and Natalio Garbi Homeostasis of dendritic cells in lymphoid organs is actively controlled by regulation of their precursors via a feed-back loop Blood First Edition Paper, prepublished online September 18, 2009; DOI 10.1182/blood-2008-11-188045 [Abstract] [PDF]   17 September 2009 Antonina V. Kurtova, Kumudha Balakrishnan, Rong Chen, Wei Ding, Susanne Schnabl, Maite P. Quiroga, Mariela Sivina, William G. Wierda, Zeev Estrov, Michael J. Keating, Medhat Shehata, Ulrich Jager, Varsha Gandhi, Neil E. Kay, William Plunkett, and Jan A. Burger Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance Blood First Edition Paper, prepublished online September 17, 2009; DOI 10.1182/blood-2009-07-233718 [Abstract] [PDF]   Georg Gruenbacher, Hubert Gander, Andrea Rahm, Walter Nussbaumer, Nikolaus Romani, and Martin Thurnher CD56+ human blood dendritic cells effectively promote TH1-type T cell responses Blood First Edition Paper, prepublished online September 17, 2009; DOI 10.1182/blood-2009-06-227256 [Abstract] [PDF]   Bindu Varghese, Adam Widman, James Do, Behnaz Taidi, Debra K. Czerwinski, John Timmerman, Shoshana Levy, and Ronald Levy Generation of CD8+ T cell-mediated immunity against idiotype-negative lymphoma escapees Blood First Edition Paper, prepublished online September 17, 2009; DOI 10.1182/blood-2009-05-223263 [Abstract] [PDF]   Masahiro Hiasa, Masahiro Abe, Ayako Nakano, Asuka Oda, Hiroe Amou, Shinsuke Kido, Kyoko Takeuchi, Kumiko Kagawa, Kenichiro Yata, Toshihiro Hashimoto, Shuji Ozaki, Kenzo Asaoka, Eiji Tanaka, Keiji Moriyama, and Toshio Matsumoto GM-CSF and IL-4 induce dendritic cell differentiation and disrupt osteoclastogenesis through M-CSF receptor shedding by up-regulation of TNF- converting enzyme (TACE) Blood First Edition Paper, prepublished online September 17, 2009; DOI 10.1182/blood-2009-04-215020 [Abstract] [PDF] [Supplemental Figures]   16 September 2009 Emmanuel J. Volanakis, Richard T. Williams, and Charles J. Sherr Stage-specific Arf tumor suppression in Notch1-induced T cell acute lymphoblastic leukemia Blood First Edition Paper, prepublished online September 16, 2009; DOI 10.1182/blood-2009-07-233346 [Abstract] [PDF]   Biagio De Angelis, Gianpietro Dotti, Concetta Quintarelli, Leslie E. Huye, Lan Zhang, Ming Zhang, Fabrizio Pane, Helen E. Heslop, Malcolm K. Brenner, Cliona M. Rooney, and Barbara Savoldo Generation of Epstein-Barr-virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506) Blood First Edition Paper, prepublished online September 16, 2009; DOI 10.1182/blood-2009-07-230482 [Abstract] [PDF]   Devorah C. Goldman, Alexis S. Bailey, Dana L. Pfaffle, Azzah Al Masri, Jan L. Christian, and William H. Fleming BMP4 regulates the hematopoietic stem cell niche Blood First Edition Paper, prepublished online September 16, 2009; DOI 10.1182/blood-2009-02-206433 [Abstract] [PDF] [Supplemental Figure]   Yunglin D. Ma, Changwon Park, Haibo Zhao, Kwadwo A. Oduro Jr., Xiaolin Tu, Fanxin Long, Paul M. Allen, Steven L. Teitelbaum, and Kyunghee Choi Defects in osteoblast function but no changes in long term repopulating potential of hematopoietic stem cells in a mouse chronic inflammatory arthritis model Blood First Edition Paper, prepublished online September 16, 2009; DOI 10.1182/blood-2008-12-196311 [Abstract] [PDF] [Supplemental Methods, Table, and Figures]   15 September 2009 Thomas Enzler, Arnon P. Kater, Weizhou Zhang, George F. Widhopf II, Han-Yu Chuang, Jason Lee, Esther Avery, Carlo M. Croce, Michael Karin, and Thomas J. Kipps Chronic lymphocytic leukemia of Eµ-TCL1 transgenic mice undergoes rapid cell-turnover that can be offset by extrinsic CD257 to accelerate disease progression Blood First Edition Paper, prepublished online September 15, 2009; DOI 10.1182/blood-2009-06-230169 [Abstract] [PDF]   Bruno Paiva, Maria-Belen Vidriales, Gema Mateo, Jose J. Perez, Maria Angeles Montalban, Anna Sureda, Laura Montejano, Norma C. Gutierrez, Alfonso Garcia de Coca, Natalia de las Heras, Maria Victoria Mateos, Maria Consuelo Lopez-Berges, Raimundo Garcia-Boyero, Josefina Galende, Jose Hernandez, Luis Palomera, Dolores Carrera, Rafael Martinez, Javier de la Rubia, Alejandro Martin, Yolanda Gonzalez, Joan Blade, Juan Jose Lahuerta, Alberto Orfao, and Jesus F. San Miguel The persistence of immunophenotypically normal residual bone marrow plasma cells at diagnosis identifies a good prognostic subgroup of symptomatic multiple myeloma patients Blood First Edition Paper, prepublished online September 15, 2009; DOI 10.1182/blood-2009-05-221689 [Abstract] [PDF] [Supplemental Appendix]   Zhigang Li, Wei Zhang, Minyuan Wu, Shanshan Zhu, Chao Gao, Lin Sun, Ruidong Zhang, Nan Qiao, Huiling Xue, Yamei Hu, Shilai Bao, Huyong Zheng, and Jing-Dong J. Han Gene expression-based classification and regulatory networks of pediatric acute lymphoblastic leukemia Blood First Edition Paper, prepublished online September 15, 2009; DOI 10.1182/blood-2009-04-218123 [Abstract] [PDF] [Supplemental Methods and Tables] [Additional Supplemental Tables and Supplemental Figure]   Ryan M. Young, Avital Polsky, and Yosef Refaeli TC-PTP is required for the maintenance of MYC-driven B-cell lymphomas Blood First Edition Paper, prepublished online September 15, 2009; DOI 10.1182/blood-2008-12-196709 [Abstract] [PDF]   14 September 2009 Neelam Yadav, Sumod K, Suresh Kumar, Manish Jain, Ashutosh Halder, Renu Saxena, and Asok Mukhopadhyay The therapeutic effect of bone marrow-derived liver cells in the phenotypic correction of murine hemophilia A Blood First Edition Paper, prepublished online September 14, 2009; DOI 10.1182/blood-2009-02-202788 [Abstract] [PDF] [Supplemental Methods and Figures]   Yun Shin Chung, Hye Joung Kim, Tae-Min Kim, Sung-Hyun Hong, Kyung-Rim Kwon, Sungwhan An, Jung-Hoon Park, Suman Lee, and Il-Hoan Oh Undifferentiated hematopoietic cells are characterized by a genome-wide under-methylation dip around the transcription start-site and a hierarchical epigenetic plasticity Blood First Edition Paper, prepublished online September 14, 2009; DOI 10.1182/blood-2009-01-197780 [Abstract] [PDF] [Supplemental Tables and Figures]   Kathleen Szczur, Yi Zheng, and Marie-Dominique Filippi The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signaling Blood First Edition Paper, prepublished online September 14, 2009; DOI 10.1182/blood-2008-12-195164 [Abstract] [PDF]   11 September 2009 Alexander Shimabukuro-Vornhagen, Michael J. Hallek, Rainer F. Storb, and Michael S. von Bergwelt-Baildon The role of B Cells in the pathogenesis of graft-versus-host disease Blood First Edition Paper, prepublished online September 11, 2009; DOI 10.1182/blood-2008-10-161638 [Abstract] [PDF]   10 September 2009 George A. Calin and Carlo M. Croce Chronic lymphocytic leukemia: interplay between non-coding RNAs and protein-coding genes Blood First Edition Paper, prepublished online September 10, 2009; DOI 10.1182/blood-2009-07-192740 [Abstract] [PDF]   David A. Jacobsohn, Andrew L. Gilman, Alfred Rademaker, Brittan Browning, Michael Grimley, Leslie Lehmann, Eneida R. Nemecek, Kimberly Thormann, Kirk R. Schultz, and Georgia B. Vogelsang Evaluation of pentostatin in corticosteroid-refractory chronic graft-versus-host disease in children: a Pediatric Blood and Marrow Transplant Consortium study Blood First Edition Paper, prepublished online September 10, 2009; DOI 10.1182/blood-2009-05-224840 [Abstract] [PDF] [Supplemental Table]   Evgeny Arons, Tara Suntum, Maryalice Stetler-Stevenson, and Robert J. Kreitman VH4-34+ hairy cell leukemia, a new variant with poor prognosis despite standard therapy Blood First Edition Paper, prepublished online September 10, 2009; DOI 10.1182/blood-2009-01-201731 [Abstract] [PDF]   9 September 2009 Susan R. Kahn How I manage the post thrombotic syndrome Blood First Edition Paper, prepublished online September 9, 2009; DOI 10.1182/blood-2009-07-199174 [Abstract] [PDF]   Isabelle I. Salles, Tim Thijs, Christine Brunaud, Simon F. De Meyer, Johan Thys, Karen Vanhoorelbeke, and Hans Deckmyn Human platelets produced in NOD/SCID mice upon transplantation of human cord blood CD34+ cells are functionally active in an ex vivo flow model of thrombosis Blood First Edition Paper, prepublished online September 9, 2009; DOI 10.1182/blood-2009-02-205989 [Abstract] [PDF] [Supplemental Table, Figures, and Videos]   8 September 2009 Ha-Jeong Kim, Pan-Kyung Kim, Sang Mun Bae, Hye-Nam Son, Thoudam Debraj Singh, Jung-Eun Kim, Byung-Heon Lee, Rang-Woon Park, and In-San Kim TGFBIp/ig-h3 activates platelets and promotes thrombogenesis Blood First Edition Paper, prepublished online September 8, 2009; DOI 10.1182/blood-2009-03-212415 [Abstract] [PDF] [Supplemental Figures]   4 September 2009 Anja Mottok, Christoph Renne, Marc Seifert, Elsie Oppermann, Wolf Bechstein, Martin-Leo Hansmann, Ralf Kuppers, and Andreas Brauninger Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B cell lymphoma entities Blood First Edition Paper, prepublished online September 4, 2009; DOI 10.1182/blood-2009-06-225839 [Abstract] [PDF]   3 September 2009 Ravin J. Garg, Hagop Kantarjian, Susan O'Brien, Alfonso Quintas-Cardama, Stefan Faderl, Zeev Estrov, and Jorge Cortes The use of nilotinib or dasatinib after failure to two prior tyrosine kinase inhibitors (TKI): long-term follow-up Blood First Edition Paper, prepublished online September 3, 2009; DOI 10.1182/blood-2009-05-221531 [Abstract] [PDF]   Julio D. Amigo, Gabriele E. Ackermann, John J. Cope, Ming Yu, Jeffrey D. Cooney, Dongdong Ma, Nathaniel B. Langer, Ebrahim Shafizadeh, George C. Shaw, Wyatt Horsley, Nikolaus S. Trede, Alan J. Davidson, Bruce A. Barut, Yi Zhou, Sarah A. Wojiski, David Traver, Tyler B. Moran, George Kourkoulis, Karl Hsu, John P. Kanki, Dhvanit I. Shah, Hui Feng Lin, Robert I. Handin, Alan B. Cantor, and Barry H. Paw The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish Blood First Edition Paper, prepublished online September 3, 2009; DOI 10.1182/blood-2008-12-189910 [Abstract] [PDF] [Supplemental Methods, Tables, and Figures]   2 September 2009 Paul A. McEwan, Robert K. Andrews, and Jonas Emsley Glycoprotein Ib inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism Blood First Edition Paper, prepublished online September 2, 2009; DOI 10.1182/blood-2009-05-224170 [Abstract] [PDF] [Supplemental Methods, Table, Figure, and Videos]   Jan Van den Bossche, Pieter Bogaert, Jolanda van Hengel, Christopher J Guerin, Geert Berx, Kiavash Movahedi, Rafael Van den Bergh, Anna Pereira-Fernandes, Jan M.C. Geuns, Hanspeter Pircher, Pierre Dorny, Johan Grooten, Patrick De Baetselier, and Jo A. Van Ginderachter Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes Blood First Edition Paper, prepublished online September 2, 2009; DOI 10.1182/blood-2009-05-221598 [Abstract] [PDF] [Supplemental Methods and Figures] [Additional Supplemental Figures]   1 September 2009 Victor R. Gordeuk, Andrew Campbell, Sohail Rana, Mehdi Nouraie, Xiaomei Niu, Caterina P. Minniti, Craig Sable, Deepika Darbari, Niti Dham, Onyinye Onyekwere, Tatiana Ammosova, Sergei Nekhai, Gregory J. Kato, Mark T. Gladwin, and Oswaldo L. Castro Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease Blood First Edition Paper, prepublished online September 1, 2009; DOI 10.1182/blood-2009-04-218040 [Abstract] [PDF]   31 August 2009 Niklas Beyersdorf, Xin Ding, Thomas Hunig, and Thomas Kerkau Superagonistic CD28 stimulation of allogeneic T cells protects from acute graft versus host disease Blood First Edition Paper, prepublished online August 31, 2009; DOI 10.1182/blood-2009-04-218248 [Abstract] [PDF] [Supplemental Methods and Figure]   Thomas V. Adamkiewicz, Miguel R. Abboud, Carole Paley, Nancy Olivieri, Melanie Kirby-Allen, Elliott Vichinsky, James F. Casella, Ofelia A. Alvarez, Julio C. Barredo, Margaret T. Lee, Rathi V. Iyer, Abdullah Kutlar, Kathleen M. McKie, Virgil McKie, Nadine Odo, Beatrice Gee, Janet L. Kwiatkowski, Gerald M. Woods, Thomas Coates, Winfred Wang, and Robert J. Adams Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are non-linear, and are associated with iron load and liver injury Blood First Edition Paper, prepublished online August 31, 2009; DOI 10.1182/blood-2009-02-203323 [Abstract] [PDF]   27 August 2009 Lesley-Ann Sutton, Efterpi Kostareli, Anastasia Hadzidimitriou, Nikos Darzentas, Athanasios Tsaftaris, Achilles Anagnostopoulos, Richard Rosenquist, and Kostas Stamatopoulos Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen Blood First Edition Paper, prepublished online August 27, 2009; DOI 10.1182/blood-2009-05-221309 [Abstract] [PDF] [Supplemental Tables and Figures]   Marc Bajenoff and Ronald N. Germain B cell follicle development remodels the conduit system and allows soluble antigen delivery to follicular dendritic cells Blood First Edition Paper, prepublished online August 27, 2009; DOI 10.1182/blood-2009-06-229567 [Abstract] [PDF] [Supplemental Figure]   Gerard Socie and Bruce R Blazar Acute graft-versus-host disease; from the bench to the bedside Blood First Edition Paper, prepublished online August 27, 2009; DOI 10.1182/blood-2009-06-204669 [Abstract] [PDF]   26 August 2009 Vinod Pullarkat Objectives of iron chelation therapy in myelodysplastic syndromes: more than meets the eye? Blood First Edition Paper, prepublished online August 26, 2009; DOI 10.1182/blood-2009-07-234062 [Abstract] [PDF]   Robert C. Doebele, Frank T. Schulze-Hoepfner, Jia Hong, Alexandre Chlenski, Benjamin D. Zeitlin, Kushboo Goel, Suzana Gomes, Yuru Liu, Mark K. Abe, Jacques E. Nor, Mark W. Lingen, and Marsha Rich Rosner A novel interplay between Epac/Rap1 and MEK5/ERK5 regulates thrombospondin to control angiogenesis Blood First Edition Paper, prepublished online August 26, 2009; DOI 10.1182/blood-2009-04-217042 [Abstract] [PDF]   24 August 2009 Christoph Licht, Fred G. Pluthero, Ling Li, Hilary Christensen, Sandra Habbig, Bernd Hoppe, Denis F. Geary, Peter F. Zipfel, and Walter H.A. Kahr Platelet-associated complement factor H in normal individuals and patients with atypical HUS Blood First Edition Paper, prepublished online August 24, 2009; DOI 10.1182/blood-2009-03-205096 [Abstract] [PDF]   20 August 2009 H Miles Prince, Sean Whittaker, and Richard T Hoppe How we treat mycosis fungoides and Sezary syndrome Blood First Edition Paper, prepublished online August 20, 2009; DOI 10.1182/blood-2009-07-202895 [Abstract] [PDF]   Oliver Soehnlein, Lennart Lindbom, and Christian Weber Mechanisms underlying neutrophil-mediated monocyte recruitment Blood First Edition Paper, prepublished online August 20, 2009; DOI 10.1182/blood-2009-06-221630 [Abstract] [PDF]   19 August 2009 Herve Falet, Michael P. Marchetti, Karin M. Hoffmeister, Michel J. Massaad, Raif S. Geha, and John H. Hartwig Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP Blood First Edition Paper, prepublished online August 19, 2009; DOI 10.1182/blood-2009-02-202721 [Abstract] [PDF]   11 August 2009 Ivana De Domenico, Diane McVey Ward, and Jerry Kaplan Specific iron chelators determine the route of ferritin degradation Blood First Edition Paper, prepublished online August 11, 2009; DOI 10.1182/blood-2009-05-224188 [Abstract] [PDF] [Supplemental Figure]   10 August 2009 Sivasubramanian Baskar, Jessica M. Suschak, Ivan Samija, Ramaprasad Srinivasan, Richard W. Childs, Steven Z. Pavletic, Michael R. Bishop, and Christoph Rader A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display Blood First Edition Paper, prepublished online August 10, 2009; DOI 10.1182/blood-2009-05-222786 [Abstract] [PDF]   Francesco Forconi, Elisa Sozzi, Emanuele Cencini, Francesco Zaja, Tamara Intermesoli, Caterina Stelitano, Luigi Rigacci, Filippo Gherlinzoni, Renato Cantaffa, Anna Baraldi, Andrea Gallamini, Alfonso Zaccaria, Alessandro Pulsoni, Marco Gobbi, Maristella Tassi, Donatella Raspadori, Lorenzo Leoncini, Andrea Rinaldi, Elena Sabattini, Francesco Bertoni, Stefano A. Pileri, and Francesco Lauria Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single agent cladribine and with more aggressive behavior Blood First Edition Paper, prepublished online August 10, 2009; DOI 10.1182/blood-2009-03-212449 [Abstract] [PDF] [Supplemental Tables and Figures]   7 August 2009 Ke Cheng, Paolo Sportoletti, Keisuke Ito, John G. Clohessy, Julie Teruya-Feldstein, Jeffery L. Kutok, and Pier Paolo Pandolfi The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model Blood First Edition Paper, prepublished online August 7, 2009; DOI 10.1182/blood-2009-03-208587 [Abstract] [PDF] [Supplemental Figure]   24 July 2009 Arie J Stangou, Nicholas R Banner, Bruce M Hendry, Mohamed Rela, Bernard Portmann, Julia Wendon, Mark Monaghan, Philip MacCarthy, Muriel Buxton-Thomas, Christopher J Mathias, Juris J Liepnieks, John O'Grady, Nigel D Heaton, and Merrill D Benson Hereditary fibrinogen A -chain amyloidosis: phenotypic characterization of a systemic disease and the role of liver transplantation Blood First Edition Paper, prepublished online July 24, 2009; DOI 10.1182/blood-2009-06-223792 [Abstract] [PDF]   To see an article, click its [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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